专利号:US-2013178626-A1 优先权日:2011-07-21 标题:Bootstrapping and Synthesis of Mechanosynthesis Tips 发明人:FREITAS JR ROBERT A; MERKLE RALPH C 权利人:FREITAS JR ROBERT A; MERKLE RALPH C 摘要:Processes are described for manufacturing atomically-precise tips using one or more tips in one or more mechanosynthetic reactions to create one or more atomically-precise tips. The processes may employ a variety of feedstock, binding any of a wide range of atoms to a workpiece to build the one or more atomically-precise tips. The processes result in atomically-precise mechanosynthesis tips with a wide variety of possible tip structures using a wide range of feedstock binding elements. Characteristics of such tips that may be used when designing new embodiments are also described.
专利号:US-8680388-B2 优先权日:2001-01-13 标题:Automatic recognition and matching of tempo and phase of pieces of music, and an interactive music player 发明人:BECKER FRIEDEMANN; HOLL THOMAS; KURZ MICHAEL; DIEPSTRATEN TOINE; HAVER DANIEL 权利人:BECKER FRIEDEMANN; HOLL THOMAS; KURZ MICHAEL; DIEPSTRATEN TOINE; HAVER DANIEL; NATIVE INSTRUMENTS SOFTWARE SYNTHESIS GMBH 摘要:A method of matching the tempo and phase in pieces of music which allows the conjunction of the pieces of music to form a continuous stream of music. The interactive music player which digitally executes the method of matching the tempo and phase in pieces of music is also disclosed.
专利号:WO-2025056767-A1 优先权日:2023-09-15 标题 :Process for the preparation of enantiomerically enriched aliphatic amines 发明人:BOU HAMDAN FARHAN; GODINEAU EDOUARD; SMEJKAL TOMAS; DUMEUNIER RAPHAEL; BOUSSEMGHOUNE MOHAMED ABDELOUAHAB; BLUM MATHIAS 权利人:SYNGENTA CROP PROTECTION AG 摘要:The present invention relates to a process for the preparation of enantiomerically enriched cyclobutylamines of formula (I) from α-tertiary cyclobutanones and reacting said enantiomerically enriched cyclobutylamines to enantiomerically enriched cyclobutylamides. Such compounds are useful intermediates in the synthesis of microbiocidal thiazole compounds.
专利号:US-8691790-B2 优先权日:2009-07-27 标题:Therapy of neurological inflammatory diseases with (5'-deoxy-5'-adenosyl) cobamamide, recombinant human growth hormone, interleukins IL-1, IL-6, IL-11, epidermal growth factor, and physiotherapy 发明人:BOUCHER JAMES LAYNE 权利人:BOUCHER JAMES LAYNE 摘要:A novel etiological hypothesis for Multiple Sclerosis (MS) is proposed describing autoimmune attack of ATP: Cob(I)alamin adenosyltransferase (ATR) thereby inhibiting synthesis of (5′-deoxy-5′-adenosyl)cobamide (referred to as 5′-deoxyadenosylcobalmin or AdoCbl) from Vitamin B 12 providing a basis for therapeutic design and diagnostic methods. Pharmaceutical compositions for therapy of MS, inflammatory neurological diseases and neurodegenerative diseases utilizing AdoCbl, growth hormones, immunomodulators, interleukins, other therapeutic agents, and physiotherapy are also described.
专利号:US-2011028688-A1 优先权日:2006-06-21 标 题 :Crystal structure of ox40l and ox40l complexed with ox40 receptor 发明人:HYMOWITZ SARAH; COMPAAN MCGUINN DEANNE 权利人:GENENTECH INC 摘要:The present disclosure provides crystals of and structural coordinates of mOX40L, hOX40L, hOX40 receptor and complexes thereof. The crystals and crystal structures are useful, for example, in the design and synthesis of modulators of mOX40L, hOX40L, and/or hOX40 receptor.
专利号:US-7041892-B2 优先权日:2001-06-18 标题 :Automatic generation of musical scratching effects 发明人:BECKER FRIEDEMANN 权利人:NATIVE INSTRUMENTS SOFTWARE SYNTHESIS GMBH 摘要:The invention relates to a method for generating electrical sounds and to an interactive music player. According to the invention, an audio signal in digital format, which lasts for a predeterminable length of time, is used as the starting material. The reproduction position and/or the reproduction direction and/or the reproduction speed of said signal is/are modulated automatically with respect to the rhythm using control information in different predeterminable ways, based on information concerning the musical tempo.