CAS: 1562-85-2; 1-Carboxy-7-(Dimethylamino)-3,4-Dihydroxyphenoxazin-5-Ium Chloride

该化合物是一种属于氰化物染料类别的合成染料,其特征是其充满活力的蓝色颜色,在各种应用中,特别是在生理学和显微镜中,对污渍生物组织有用;该化合物显示出核酸的强烈亲近性,允许其有选择地与DNA和RNA结合,从而增强微sc成像的对比;伽洛氰胺在水中溶解,可用于水溶,用于污渍目的;其化学结构具有芳香环和氮原子的复杂安排,有助于其染色色特性;此外,在光接触下,青青氰胺因其稳定性而闻名,适合长期研究;然而,与许多合成染料一样,由于潜在的毒性和环境考虑,应对它进行谨慎处理.

结构式图片

欧盟法规

ECHA物质C&L通报REACH预注册

合成工艺路线路线简述

    海关参考信息

    专利信息


    专利号:US-2007275962-A1
    优先权日:2003-09-10
    标 题:Heterobicyclic Compounds as Pharmaceutically Active Agents
    发明人:KOUL ANIL; KLEBL BERT; MULLER GERHARD; MISSIO ANDREA; SCHWAB WILFRIED; HAFENBRADL DORIS; NEUMANN LARS; SOMMER MARC-NICOLA; MULLER STEFAN; HOPPE EDMUND; FREISLEBEN ACHIM; BACKES ALEXANDER; HARTUNG CHRISTIAN; FELBER BEATRICE; ZECH BIRGIT; ENGKVIST OLA; KERI GYORGY; ORFI LASZLO; BANHEGYI PETER; GREFF ZOLTAN; HORVATH ZOLTAN; VARGA ZOLTAN; MARKO PETER; PATO JANOS; SZABADKAI ISTVAN; SZEKELYHID ZSOLT; WACZEK FRIGYES
    权利人:GPC BIOTECH AG
    摘要:Described are heterobicyclic compounds such as 4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acid amides, 4,7-dihydro-5H-thieno[2,3-c]thiopyran 3-carboxylic acid amides, 4,7-dihydro-5H-thieno[2,3-c]pyran-3-carboxylic acid amides, or benzo[b]thiophene-3-carboxylic acid amides and pharmaceutically acceptable salts thereof, the use of these derivatives for the prophylaxis and/or treatment of various diseases such as infectious diseases, including mycobacteriainduced infections and opportunistic diseases, prion diseases, immunological diseases, autoimmune diseases, bipolar and clinical disorders, cardiovascular diseases, cell proliferative diseases, diabetes, inflammation, transplant rejections, erectile dysfunction, neurodegenerative diseases and stroke, as well as compositions containing at least one heterobicyclic compound and/or pharmaceutically acceptable salts thereof. Furthermore, reaction procedures for the synthesis of the heterobicyclic compound are disclosed.

    专利号:US-11608340-B2
    优先权日:2014-11-17
    标 题 :Nanomaterial compositions, synthesis, and assembly
    发明人:CHEN QIAN; YU HONGCHUAN; CHEN YUPENG
    权利人:RHODE ISLAND HOSPITAL
    摘要:Compositions or an assembly of a series of biomimetic compounds include chemical structures that mimic or structurally resemble a nucleic acid base pair. Complexes of nanotubes and agents are useful to deliver agents into the cells or bodily tissues of individuals for therapeutic and diagnostic purposes. Exemplary compounds include those of Formula (I), (III), (V) or (VII), or of Formula (II), (IV), (VI) or (VIII).
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    合成参考文献


    参考文献:10.1073/pnas.0707130104
    摘要:Betzi S, Restouin A, Opi S, Arold ST, Parrot I, Guerlesquin F, Morelli X, Collette Y. Protein protein interaction inhibition (2P2I) combining high throughput and virtual screening: Application to the HIV-1 Nef protein. Proc Natl Acad Sci U S A. 2007 Dec 04;104(49):19256–61.
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