专利号:US-7700654-B2 优先权日:2005-02-05 标 题:Isolation of N-butylbenzenesulfonamide, synthesis of benzenesulfonamide derivatives, and use of N-butylbenzenesulfonamide and benzenesulfonamide derivatives for treating benign prostatic hyperplasia and/or prostate carcinoma 发明人:HOFFMANN HANS-RAINER; MATUSCH RUDOLF; BANIAHMAD ARIA 权利人:LOHMANN THERAPIE SYST LTS 摘要:A process for isolating N-butylbenzenesulfonamide (NBBS) from biological material, the chemical synthesis of benzenesulfonamide derivatives, the use of NBBS and benzenesulfonamide derivatives for treating benign prostatic hyperplasia and/or prostate carcinoma, the production of medicaments for the treatment thereof, and the use of NBBS and benzenesulfonamide derivatives as a lead substance in the development of active substances for treating benign prostatic hyperplasia and/or prostate carcinoma are provided.
专利号:US-2023192718-A1 优先权日:2018-03-30 标 题 :Bicyclic enone carboxylates as modulators of transporters and uses thereof 发明人:SANDANAYAKA VINCENT 权利人:NIROGY THERAPEUTICS INC 摘要:The invention generally relates to the field of monocarboxylate transporter inhibitors, and more particularly to new bicyclic enone carboxylate enone compounds, the synthesis and use of these compounds and their pharmaceutical compositions, e.g., in the treatment, modulation and/or prevention of physiological conditions associated with monocarboxylate transporter activity such as in treating cancer and other neoplastic disorders, tissue and organ transplant rejection.
专利号:US-2008177107-A1 优先权日:2005-02-05 标题 :Isolation of N-Butylbenzenesulfonamide, Synthesis of Benzenesulfonamide Derivatives, and Use of N-Butylbenzenesulfonamide and Benzenesulfonamide Derivatives for Treating Benign Prostatic Hyperplasia and/or Prostate Carcinoma
专利号:AU-2006210040-B2 优先权日:2005-02-05 标 题:Isolation of N-butylbenzenesulfonamide, synthesis of benzenesulfonamide derivatives, and use of N-butylbenzenesulfonamide and benzenesulfonamide derivatives for the treatment of benign prostate hyperplasia and/or prostate carcinoma
专利号:AU-2006210040-A1 优先权日:2005-02-05 标题 :Isolation of N-butylbenzenesulfonamide, synthesis of benzenesulfonamide derivatives, and use of N-butylbenzenesulfonamide and benzenesulfonamide derivatives for the treatment of benign prostate hyperplasia and/or prostate carcinoma
专利号:AU-2006210040-B9 优先权日:2005-02-05 标题 :Isolation of N-butylbenzenesulfonamide, synthesis of benzenesulfonamide derivatives, and use of N-butylbenzenesulfonamide and benzenesulfonamide derivatives for the treatment of benign prostate hyperplasia and/or prostate carcinoma
[参考文献]: S V Ley, Et Al. Polymer Supported Reagents In Synthesis: Preparation Of Bicyclo[2.2.2] Octane Derivates Via Tandem Michael Addition Reactions And Subsequent Combinatorial Decoration. J Comb Chem. 2000 Mar-Apr;2(2):104-7.
合成参考文献
摘要:Shcherbakova, I., Science of Synthesis, (2007) 31, 783. 摘要:Shcherbakova, I., Science of Synthesis, (2007) 31, 786. 摘要:Shcherbakova, I., Science of Synthesis, (2007) 31, 812.