间二三氟甲苯置于氯化亚砜体系中,化学反应生成 3,5-双三氟甲基苯甲酰氯 参考文献:Lichtenberger,J.; Weiss,F.,Bulletin De La Societe Chimique De France,1962,P. 587-593 标题:Lichtenberger,J.; Weiss,F.,Bulletin De La Societe Chimique De France,1962,P. 587-593
专利号:US-6350915-B1 优先权日:1999-06-11 标 题:Process for the synthesis of 1-(3,5-bis(trifluoromethyl)-phenyl)ethan-1-one 发明人:CVETOVICH RAYMOND 权利人:MERCK & CO INC 摘要:The present invention is concerned with a novel process for the preparation of 1-(3,5-bis(trifluromethyl)phenyl)ethan-1-one (CAS 30071-93-3). This compound is useful as an intermediate in the synthesis of therapeutic agents.
专利号:US-2024067621-A1 优先权日:2021-02-23 标 题:Polyfluorinated cannabinoid and cannabinoid-like compounds and methods of synthesis and use thereof 发明人:WEAVER JIMMIE D; DAY JON; GROTJAHN SASCHA; SENAWEERA SAMEERA; KOENIG BURKHARD 权利人:WEAVER JIMMIE D; DAY JON; GROTJAHN SASCHA; SENAWEERA SAMEERA; KOENIG BURKHARD; THE BOARD OF REGENTS FOR THE OKLAHOMA AGRICULTURAL AND MECH COLLEGES 摘要:Polyfluorinated compounds are disclosed, including polyfluorinated cannabinoid and cannabinoid-like compounds. Also disclosed are methods of producing the polyfluorinated compounds.
专利号:US-2016194279-A1 优先权日:2012-12-09 标 题 :One pot process for the conversion of aroyl chlorides to acyl thioureas 发明人:CHEPURI VENKATA RAMANA; BEERAN SENTHILKUMAR 权利人:COUNCIL SCIENT IND RES 摘要:The present invention disclose an improved one pot process for synthesis of acyl thioureas of formula (I), with yield greater than 80%, from aroyl chlorides of formula (I) wherein, R′ is an aryl or a heteroarylene group substituted with one or more groups selected from hydrogen, alkyl, alkylene, alkynyl, alkoxy, alkenyloxy, halo, hydroxyl, nitro, amino, carboxyl, ester, halogenated hydrocarbon or an aryl or heteroaryl; R″ and R′″ are selected independently from hydrogen, alkyl, alkylene, alkynyl, alkoxy, alkenyloxy, halo, hydroxyl, nitro, amino or halogenated hydrocarbon.
专利号:ES-2355849-T3 优先权日:2006-04-13 标 题:SYNTHESIS OF ACILAMINO ALKENYLENE USEFUL AMIDAS AS SUBSTANCE ANTAGONISTS P.
专利号:CA-2645362-A1 优先权日:2006-04-13 标题:Synthesis of acylaminoalkenylene amides useful as substance p antagonists
专利号:CA-2645362-C 优先权日:2006-04-13 标 题 :Synthesis of acylaminoalkenylene amides useful as substance p antagonists