专利号:US-2023312617-A1 优先权日:2020-07-25 标题 :Process for synthesis of organosilicon compounds from halosilanes 发明人:DOLAI SUKANTA; BHAT SHREEDHAR; TARAFDAR GOURAV 权利人:MOMENTIVE PERFORMANCE MAT INC 摘要:A process for synthesis of an organosilicon compound is provided herein. Also, novel organosilicon compounds prepared by the present process is provided herein. The process comprises the reaction of a halosilane with an organofunctional alkyl halide in the presence of a metal catalyst, a promoter, and an optional co-catalyst. The process provides an efficient synthetic route to produce organosilicon compounds. The process also allows synthesis of organosilicon compounds with a plurality of different functional groups.
专利号:US-11639349-B2 优先权日:2020-05-28 标题:Stereoselective synthesis of intermediate for preparation of heterocyclic compound 发明人:CHEN WEN-CHANG; HSU HAN-PEI; CHOU SHAN-YEN; CHUANG SHIH-CHIEH; YEN CHI-FENG 权利人:TAI GEN BIOTECHNOLOGY CO LTD; TAIGEN BIOPHARMACEUTICALS CO BEIJING LTD; TAIGEN BIOTECHNOLOGY CO LTD 摘要:Provided is a stereoselective synthesis of an intermediate for the preparation of the heterocyclic derivative as a Cap-dependent endonuclease inhibitor. The synthesis process has the advantages of simple operation, higher yield and relatively controllable steroselectivity, such that it is suitable for large-scale production.
专利号:WO-2024012791-A1 优先权日:2022-07-11 标题 :Electrochemical synthesis of pyrazolines and pyrazoles 发明人:BÄR ROBIN MAXIMILIAN; FORD MARK JAMES; KALDAS SHERIF JAMES; WALDVOGEL SIEGFRIED; HOFMANN SILJA; LINDEN MARTIN 权利人:BAYER AG 摘要:The present invention relates to an electrochemical process for the synthesis of pyrazolines and pyrazoles of formula (I). The process can be especially used for the synthesis of the herbicide safener mefenpyr-diethyl.
专利号:US-2025179012-A1 优先权日:2022-03-04 标 题:Synthesis of sulfur(vi) compounds and reagents for same 发明人:LOPCHUK JUSTIN MATTHEW; SHULTZ ZACHARY 权利人:H LEE MOFFITT CANCER CT & RES 摘要:This disclosure provides reagents and processes for the synthesis of organic compounds, more particularly reagents and processes for the asymmetric synthesis of sulfur (VI) containing organic compounds.
专利号:US-2023183223-A1 优先权日:2020-05-14 标题:Process for the synthesis of n-butyloxycarbonyl-3-(4-imidazol-1- ylmethylphenyl)-5-iso-butylthiophene-2-sulfonamide 发明人:CERNAKS DMITRIJS; DEGE ELIZA 权利人:VICORE PHARMA AB 摘要:There is provided a new process for the synthesis of compounds of formula I, which are useful as angiotensin (Ang II) type 2 receptor agonists: by reacting a compound of formula II, with an excess of a compound of formula III, wherein W, Z and X have meanings given in the description; followed by reaction of the intermediate so formed with a suitable source of the counter-ion, W.
专利号:US-8492390-B2 优先权日:2002-05-08 标题 :Synthesis of locked nucleic acid derivatives 发明人:DETLEF SORENSEN MADS; WENGEL JESPER; KOCH TROELS; CHRISTENSEN SIGNE M; ROSENBOHM CHRISTOPH; PEDERSEN DANIEL SEJER 权利人:DETLEF SORENSEN MADS; WENGEL JESPER; KOCH TROELS; CHRISTENSEN SIGNE M; ROSENBOHM CHRISTOPH; PEDERSEN DANIEL SEJER; SANTARIS PHARMA AS 摘要:The invention relates to a novel strategy for the synthesis of Locked Nucleic Acid derivatives, such as α- L -oxy-LNA, amino-LNA, α- L -amino-LNA, thio-LNA, α- L -thio-LNA, seleno-LNA and methylene LNA, which provides scalable high yielding reactions utilising intermediates that also can produce other LNA analogues such as oxy-LNA. Also, the compounds of the formula X are important intermediates that may be reacted with varieties of nucleophiles leading to a wide variety of LNA analogues.
[参考文献]: Carmen Cavallo, Et Al. Solid Solutions Of Rare Earth Cations In Mesoporous Anatase Beads And Their Performances In Dye-Sensitized Solar Cells. Sci Rep. 2015 Nov 18:5:16785. [参考文献]: Jessica Le Ven, Et Al. Identification Of The Environmental Neurotoxins Annonaceous Acetogenins In An Annona Cherimolia Mill. Alcoholic Beverage Using Hplc-Esi-Ltq-Orbitrap. J Agric Food Chem. 2014 Aug 27;62(34):8696-704. [参考文献]: Jianjian Lin, Et Al. 3D Hierarchical Rutile Tio2 And Metal-Free Organic Sensitizer Producing Dye-Sensitized Solar Cells 8.6% Conversion Efficiency. Sci Rep. 2014 Aug 29:4:5769. [参考文献]: Jung-Che Tsai, Et Al. Fabrication Of Mesoporous Cos2 Nanotube Arrays As The Counter Electrodes Of Dye-Sensitized Solar Cells. Chem Asian J. 2015 Sep;10(9):1932-9. [参考文献]: Yu-Il Kang, Et Al. In Situ Poly(Methyl Methacrylate)/graphene Composite Gel Electrolytes For Highly Stable Dye-Sensitized Solar Cells. Chemsuschem. 2015 Nov;8(22):3799-804.
合成参考文献
摘要:Hirsch, A.; Vostrowsky, O., Science of Synthesis, (2008) 43, 54. 摘要:Takeda, T.; Tsubouchi, A., Science of Synthesis, (2009) 46, 82. 摘要:Schramm, M. P., Science of Synthesis, (2009) 46, 477. 摘要:Cherkinsky, M.; Levinger, S., Science of Synthesis, (2010) 47, 501. 摘要:Cherkinsky, M.; Levinger, S., Science of Synthesis, (2010) 47, 494.