专利号:WO-2023102600-A1 优先权日:2021-12-06 标题:Synthesis of amphiphilic block copolymers and polymeric nanofibers produced therefrom 发明人:ZETTERLUND PER B; ISHIZUKA FUMI; KIM HYUN JIN; CHATANI SHUNSUKE; NIINO HIROSHI 权利人:NEWSOUTH INNOVATIONS PTY LTD 摘要:The present disclosure relates to the field of synthesis of block copolymers, and polymeric nanofibers having a core-shell morphology produced therefrom. The present disclosure relates to the field of synthesis of block copolymers where one block is more hydrophobic than the other block and is a different composition. The disclosure also relates to uses of these polymeric nanofibers in various applications, such as reinforcing a polymeric matrix and for coatings applications.
专利号:US-6423877-B1 优先权日:1999-11-15 标题:Synthesis of pseudopterosin compounds 发明人:COREY ELIAS J 权利人:HARVARD COLLEGE 摘要:The present invention is directed to a new synthetic route to pseudopterosin aglycone (3): n a key intermediate for the synthesis of a group of antiinflammatory natural products including pseudopterosin A (1) and E (2). The pathway of synthesis starts with the abundant and inexpensive (S)-(−)-limonene and its long-known cyclic hydroboration product (4) and leads to the chiral hydroxy ketone (6). Conversion of (6) to (10) followed by a novel aromatic annulation produced (15) which underwent highly diastereoselective cyclization to afford the protected pseudopterosin aglycone (16). The naturally occurring pseudopterosins such as (1) and (2) are readily available from this key intermediate.
专利号:WO-2009003796-A1 优先权日:2007-06-29 标 题:Method for the synthesis of neral by the isomerization of isocitrals 发明人:SCHMIDT-LEITHOFF JOACHIM; JAEKEL CHRISTOPH; PACIELLO ROCCO; HEYDRICH GUNNAR; HEIDEMANN THOMAS 权利人:BASF SE; SCHMIDT-LEITHOFF JOACHIM; JAEKEL CHRISTOPH; PACIELLO ROCCO; HEYDRICH GUNNAR; HEIDEMANN THOMAS 摘要:The present invention relates to a method for the synthesis of neral and/or geranial by the isomerization of one or more isocitrals. In particular, the invention relates to a method for the synthesis of neral in pure or enriched form, starting out from a mixture of materials containing neral and geranial and one or more isocitrals.
专利号:US-4151205-A 优先权日:1975-01-27 标题 :Synthesis of vitamin E 发明人:COHEN NOAL; SAUCY GABRIEL 权利人:HOFFMANN LA ROCHE 摘要:A synthesis of vitamin E in racemic or optically active forms from methacryolein or beta-hydroxyisobutyric acid including intermediates in this synthesis.
专利号:US-4000169-A 优先权日:1975-01-27 标题 :Asymmetric synthesis of optically active compounds 发明人:CHAN KA-KONG; SAUCY GABRIEL 权利人:HOFFMANN LA ROCHE 摘要:Asymmetric synthesis of optically active 3,7,11-trimethyl-dodecan-1-ol, an intermediate for producing optically active vitamin E, from isovaleraldehyde or prenal including intermediates in this synthesis.
专利号:US-4051153-A 优先权日:1975-01-27 标题 :Intermediates in the synthesis of vitamin E 发明人:COHEN NOAL; SAUCY GABRIEL 权利人:HOFFMANN LA ROCHE 摘要:A synthesis of vitamin E in racemic or optically active forms from methacryolein or beta-hydroxyisobutyric acid including intermediates in this synthesis.
1: Lemes RS, Alves CCF, Estevam EBB, Santiago MB, Martins CHG, Santos TCLD, Crotti AEM, Miranda MLD. Chemical composition and antibacterial activity of essential oils from Citrus aurantifolia leaves and fruit peel against oral pathogenic bacteria. An Acad Bras Cienc. 2018 Apr-Jun;90(2):1285-1292. doi: 10.1590/0001-3765201820170847. pii: E1301. doi: 10.3390/molecules23061301. doi: 10.1038/s41598-018-22395-6. 5: Chizzola R, Lohwasser U, Franz C. Biodiversity within Melissa officinalis: Variability of Bioactive Compounds in a Cultivated Collection. Molecules. 2018 Jan 31;23(2). pii: E294. doi: 10.3390/molecules23020294. doi: 10.1186/s12906-018-2085-0. 7: Oliveira JL, Campos EVR, Pereira AES, Pasquoto T, Lima R, Grillo R, Andrade DJ, Santos FAD, Fraceto LF. Zein Nanoparticles as Eco-Friendly Carrier Systems for Botanical Repellents Aiming Sustainable Agriculture. J Agric Food Chem. 2018 Feb 14;66(6):1330-1340. doi: 10.1021/acs.jafc.7b05552. Epub 2018 Feb 1. doi: 10.1016/j.micpath.2017.12.051. Epub 2017 Dec 19. doi: 10.1016/j.bioorg.2017.12.005. Epub 2017 Dec 9. pii: E2154. doi: 10.3390/molecules22122154. doi: 10.11604/pamj.2017.27.282.9679. eCollection 2017.
合成参考文献
参考文献:10.1186/1465-9921-12-92 摘要:Gao M, Singh A, Macri K, Reynolds C, Singhal V, Biswal S, Spannhake EW. Antioxidant components of naturally-occurring oils exhibit marked anti-inflammatory activity in epithelial cells of the human upper respiratory system. Respiratory Research. 2011 Dec 01;12(1):92. doi: 10.1186/1465-9921-12-92.