专利号:US-7514559-B2 优先权日:2004-03-22 标题 :Catalyst for synthesis of 2- and 4-picolines 发明人:DUTTA PASHUPATI; ROY SUBHASH CHANDRA; ROY SHYAM KISHORE; GOSWAMI TARUN KANTI 权利人:COUNCIL SCIENT IND RES 摘要:The present invention provides a catalyst composite for the synthesis of 2- and 4-picolines and a process for the preparation thereof and use thereof for the synthesis of 2- and 4-Picolines.
专利号:US-2006128930-A1 优先权日:2004-12-03 标题 :Synthesis of sterically hindered phenol based macromolecular antioxidants 发明人:DHAWAN ASHISH; CHOLLI ASHOK L 权利人:DHAWAN ASHISH; CHOLLI ASHOK L 摘要:Disclosed is a method for the synthesis of sterically hindered polymeric antioxidants based on phenol type antioxidant monomers. The method includes polymerizing and alkylating a phenol containing monomer represented by the following structural formula: n n nto produce a sterically hindered polymeric macromolecular antioxidant. X, R 10 and q are as defined herein. The disclosed method is a simple, direct and economical process for the synthesis of sterically hindered polymeric macromolecular antioxidants.
专利号:US-5352670-A 优先权日:1991-06-10 标题:Methods for the enzymatic synthesis of alpha-sialylated oligosaccharide glycosides 发明人:VENOT ANDRE P; UNGER FRANK M; KASHEM MOHAMMED A; BIRD PAUL; MAZID M ABDUL 权利人:ALBERTA RES COUNCIL 摘要:Disclosed are methods for the enzymatic synthesis of alpha-sialylated oligosaccharide glycosides. Specifically, in the disclosed methods, sialyltransferase is activated to transfer an analogue of sialic acid, employed as its CMP-nucleotide derivative, to an oligosaccharide glycoside. The analogue of sialic acid and the oligosaccharide employed in this method are selected to be compatible with the sialyltransferase employed.
专利号:US-6187949-B1 优先权日:1998-01-22 标 题 :Synthesis of lower aliphatic esters using heterpolyacids with an aldehyde-free product stream 发明人:FROOM SIMON FREDERICK THOMAS; HODGE STEPHEN ROBERT; SHARMA BHUSHAN 权利人:BP CHEM INT LTD 摘要:Process for the production of lower aliphatic esters by bringing together in an addition reaction a lower olefin and a saturated, lower aliphatic, mono-carboxylic acid in the vapor phase into contact with a heterpolyacid catalyst. The reactant olefin and acids and any recycled feeds are rendered substantially free of aldehydes impurities prior to being brought into contact with the heterpolyacid catalyst. Acetaldehyde is a catalyst poison and removal of these from the feeds prolongs life and activity of the heteropolyacid catalyst.
专利号:US-5994115-A 优先权日:1997-07-22 标 题:Artificial system for the production of infectious human papillomavirus 发明人:MEYERS CRAIG M 权利人:PENN STATE RES FOUND 摘要:Artificial systems for the production of infectious human papillomavirus allow development of diagnostic and therapeutic strategies based on replication and infectivity studies for diseases caused by these viruses. The artificial introduction of papillomavirus genomic DNA into an epithelial cell line. In particular, HPV type 18 genomic DNA is transfected into primary keratinocytes. Transfection is followed by clonal expansion of the transfected cells, and induction of epithelial stratification and differentiation in organotypic cultures resulting in the synthesis of virions. Virus particles synthesized were approximately 50 nanometers in diameter as observed by electron microscopy. In particular HPV18 virions produced by the system and purified by an isopycnic gradient were capable of infecting keratinocytes.
专利号:US-2007082039-A1 优先权日:2004-10-18 标题 :Synthesis of fatty alcohol esters of alpha-hydroxy carboxylic acids, the use of the same as percutaneous permeation enhancers, and topical gels for the transdermal delivery of steroids 发明人:JONES GERALD S JR; ST LAURENT JOSEPH P; GOODRICH SCOTT A 权利人:JONES GERALD S JR; ST LAURENT JOSEPH P; GOODRICH SCOTT A 摘要:The present invention provides a novel approach for the preparation of fatty alcohol esters of α-hydroxy carboxylic acids. The present invention also provides a novel topical gel for the transdermal delivery of steroids using the fatty alcohol esters as permeation enhancers.
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