CAS: 18942-46-6; Boc-Cys(Pmeobzl)-Oh

相似化合物

58290-35-0 141892-41-3 2544-31-2

上下游产品

CAS号24424-99-5 二碳酸二叔丁酯 | CAS号2544-31-2 S-(4-甲氧基苄基)-L-半胱氨酸 | CAS号76614-97-6 ammonium chlori... | CAS号10389-65-8 N,N'-双(叔丁氧羰基)-L-胱氨酸 | CAS号824-94-2 4-甲氧基苄氯 | CAS号58632-95-4 2-(叔-丁氧基碳酰胺)-2-苯乙腈 | CAS号1070-19-5 Carbonazidic ac... | CAS号222404-25-3 (4R)-2-(4-甲氧基苯基... | CAS号20887-95-0 B°C-L-半胱氨酸 | CAS号76880-29-0 (R)-2-((叔丁氧基羰基)... | CAS号116229-36-8 Bactenecin | CAS号77826-55-2 N,N'-Di-B°C-(L)...

N,N'-双(叔丁氧羰基)-L-胱氨酸置于盐酸,N,N-二异丙基乙胺,锌体系中,用 二氯甲烷,水,乙酸乙酯 用作溶剂,化学反应 24.0H,反应生成Boc-S-(4-甲氧基苄基)-L-半胱氨酸
参考文献:Flemer,Stevenson,Protein And Peptide Letters,2014,Vol. 21,# 12,P. 1257-1264
标题:Flemer,Stevenson,Protein And Peptide Letters,2014,Vol. 21,# 12,P. 1257-1264

专利信息

专利号:US-2004110228-A1
优先权日:2002-04-01
标 题:Combinatorial organic synthesis of unique biologically active compounds
发明人：MCALPINE SHELLI R; TAYLOR RACHEL E; BOLLA MEGAN L; SEGALL ANCA M
摘要:The invention provides a method for making a combinatorial library of cyclic compounds, such as Holliday junction-trapping compounds, comprising the steps of (a) obtaining a plurality of trimers according to the generic structure X 1- X 2- X 3 , wherein X 1 , X 2 and X 3 can be independently any naturally or nonnaturally occurring amino acids or peptidomimetics thereof; (b) optionally coupling a spacer S to the trimer at either end; (c) cyclizing two trimers or trimer-spacer conjugates in a head-to-tail orientation; thereby obtaining a combinatorial library of compounds, wherein the library does not include an unmodifed or naturally occurring Holliday Junction-trapping compounds. The invention additionally provides methods macrocyclic compounds that are synergimycin derivatives.

专利号:US-4033940-A
优先权日:1975-11-12
标 题:Cyclization of peptides
发明人：HUGHES JOHN L; SEYLER JAY K; LIU ROBERT C
权利人:ARMOUR PHARMA
摘要:The synthesis of a disulfide cyclic peptide by preparing an intermediate peptide containing an amino terminal cystine residue and a cysteine residue located in a position within the amino acid sequence, to give a desired peptide, and placing such intermediate peptide in a solution substantially free of oxygen at a pH of from about 5 to 10 until rearrangement takes place to yield a cyclic disulfide peptide and to displace a molecule of cysteine from the amino terminal cysteine residue. The disclosure also embraces said intermediate peptides as new compounds and the processes by which they are prepared.

专利号:US-4388235-A
优先权日:1982-02-12
标 题:Synthesis of peptides
发明人：ORLOWSKI RONALD C; SEYLER JAY K
权利人:ARMOUR PHARMA
摘要:New peptides are disclosed which have biological activity of the same type as known calcitonins and which have a shorter amino acid chain than natural calcitonins. Also resin peptides are disclosed which may be converted to peptides having such biological activity; and processes for producing said resin peptides and said calcitonin peptides.

专利号:US-4217268-A
优先权日:1978-07-20
标 题:Synthesis of peptides
发明人：HUGHES JOHN L; LIU ROBERT C; SEYLER JAY K
权利人:HUGHES JOHN L; LIU ROBERT C; SEYLER JAY K
摘要:A new peptide is disclosed which has biological activity of the same type as known calcitonins and which has a shorter amino acid chain than natural calcitonins. Also resin peptides are disclosed which may be converted to peptides having such biological activity; and processes for producing said resin peptides and said calcitonin peptides.

专利号:US-4062815-A
优先权日:1974-08-12
标 题:Resin peptides
发明人：HUGHES JOHN LAWRENCE; SEYLER JAY KENNETH; LIU ROBERT CHUNG-HUANG
权利人:ARMOUR PHARMA
摘要:Resin peptides useful in the preparation of salmon calcitonin are disclosed along with processes for preparing the same. The invention also embraces peptides from which the resin moiety has been cleaved and which are useful in the synthesis of salmon calcitonin together with processes for preparing the cleaved peptides. In general, the processes involve the solid phase synthesis procedures.

专利号:US-4061626-A
优先权日:1976-04-29
标题 :Somatostatin analogs and intermediates thereto
发明人：SHIELDS JAMES E
权利人:LILLY CO ELI
摘要:The tetradecapeptides in which Y is Gly or D-Ala are described along with corresponding non-toxic pharmaceutically-acceptable acid addition salts as well as intermediates useful in the synthesis of the tetradecapeptides. The tetradecapeptide in which Y is Gly as well as its pharmaceutically acceptable acid addition salts exhibit as their principal activity the in vivo inhibition of the release of gastric acid. The tetradecapeptide in which Y is D-Ala as well as its pharmaceutically acceptable acid addition salts exhibit as their principal activity the in vivo stimulation of the release of growth hormone.