CAS: 2713-33-9; 3,4-Difluorophenol

上下游产品

3,4-difluoroaniline ortho-difluorobenzene 3,4 difluorobenzaldehyde 3,4-difluoronitrobenzene 2-(3,4-difluorophenoxy)acetic acid 4-Propyl-cyclohexanecarboxylic acid 3,4-difluoro-phenyl ester Cyclopropyl-[4-(3,4-difluoro-phenoxymethyl)-piperidin-1-yl]-methanone 1-(3,4-difluorophenoxy)-2,3-epoxypropane

3,4-二氟硝基苯置于铁粉,氯化铵体系中,化学反应生成3,4-二氟苯酚
参考文献:Aromatic Fluorine Compounds. Viii. Plant Growth Regulators And Intermediates1,2
标题:Aromatic Fluorine Compounds. Viii. Plant Growth Regulators And Intermediates1,2
摘要:
Doi:10.1021/ja01510A021

专利信息

专利号:US-2004110228-A1
优先权日:2002-04-01
标 题:Combinatorial organic synthesis of unique biologically active compounds
发明人：MCALPINE SHELLI R; TAYLOR RACHEL E; BOLLA MEGAN L; SEGALL ANCA M
摘要:The invention provides a method for making a combinatorial library of cyclic compounds, such as Holliday junction-trapping compounds, comprising the steps of (a) obtaining a plurality of trimers according to the generic structure X 1- X 2- X 3 , wherein X 1 , X 2 and X 3 can be independently any naturally or nonnaturally occurring amino acids or peptidomimetics thereof; (b) optionally coupling a spacer S to the trimer at either end; (c) cyclizing two trimers or trimer-spacer conjugates in a head-to-tail orientation; thereby obtaining a combinatorial library of compounds, wherein the library does not include an unmodifed or naturally occurring Holliday Junction-trapping compounds. The invention additionally provides methods macrocyclic compounds that are synergimycin derivatives.

专利号:US-7816375-B2
优先权日:2000-09-11
标 题 :Ligands for monoamine receptors and transporters, and methods of use thereof
发明人：AQUILA BRIAN M; BANNISTER THOMAS D; CUNY GREGORY D; HAUSKE JAMES R; HOLLAND JOANNE M; PERSONS PAUL E; RADEKE HEIKE; WANG FENGJIANG; SHAO LIMING
权利人:SEPRACOR INC
摘要:One aspect of the present invention relates to heterocyclic compounds. A second aspect of the present invention relates to the use of the heterocyclic compounds as ligands for various mammalian cellular receptors, including dopamine, serotonin, or norepinephrine transporters. The compounds of the present invention will find use in the treatment of numerous ailments, conditions and diseases which afflict mammals, including but not limited to addiction, anxiety, depression, sexual dysfunction, hypertension, migraine, Alzheimer's disease, obesity, emesis, psychosis, schizophrenia, Parkinson's disease, inflammatory pain, neuropathic pain, Lesche-Nyhane disease, Wilson's disease, and Tourette's syndrome. An additional aspect of the present invention relates to the synthesis of combinatorial libraries of the heterocyclic compounds, and the screening of those libraries for biological activity, e.g., in assays based on dopamine transporters.

专利号:WO-2025125811-A1
优先权日:2023-12-12
标题:Heterocyclic compounds and their use for the treatment of neurological disorders
发明人：PLOWRIGHT ALLEYN THOMAS; PFEIFFER THOMAS; MÄRCHER-RØRSTED EMIL; DUCKWORTH EDWARD JOSEPH
权利人:ONTRACK THERAPEUTICS LTD
摘要:The present invention relates to novel synthetic compounds of Formula (I) and (II) related to naturally occurring flavonoids such as 7,8-dihydroxyflavone (7,8-DHF). The invention further relates to the method of synthesis, the use of these compounds as research tools and their use as pharmaceuticals.

专利号:EP-1695964-A1
优先权日:2000-11-15
标题 :Quinoline derivatives for use as intermediates in the synthesis of heterocyclylalcoyl piperidines

专利号:CN-1247191-A
优先权日:1993-06-14
标题 :Imidazole compounds as raw materials for the synthesis of imidazole lipoxygenase inhibitors