CAS: 542-05-2; 3-Oxopentanedioic Acid

相似化合物

105-50-0 1830-54-2 28009-80-5

上下游产品

CAS号77-92-9 柠檬酸 | CAS号53798-96-2 1,5-Dimethyl Citrate | CAS号115996-74-2 3-carboxymethyl... | CAS号105-50-0 丙酮二羧酸二乙酯 | CAS号7664-93-9 硫酸 | CAS号861570-37-8 2,4-dibenzoyl-3... | CAS号7732-18-5 水 | CAS号7705-08-0 三氯化铁 | CAS号32328-03-3 3-羟基戊二酸二乙酯 | CAS号423165-07-5 (1R,3s,5S)-3-(3... | CAS号4390-39-0 9-氮杂双环[3.3.1]壬烷-3-酮 | CAS号5932-53-6 6-羟基托品酮 | CAS号33369-45-8 3-羧基-1,4-二甲基-吡咯-2-乙酸 | CAS号376348-67-3 N-(8-苄基-8-氮杂双环[... | CAS号423165-13-3 8-苄基-3-外型-(5-异丙... | CAS号454-14-8 红古豆碱 | CAS号110-94-1 戊二酸 | CAS号141-82-2 丙二酸

柠檬酸置于硫酸体系中,化学反应 0.5H,反应生成 1,3-丙酮二羧酸
参考文献:反式 1,2-双香豆基乙烯的区域特异性正 Diels-Alder 反应
标题:反式 1,2-双香豆基乙烯的区域特异性正 Diels-Alder 反应
摘要:在哌啶的存在下,不同的 7,8-取代香豆素 4-乙酸与 7-二乙基氨基香豆素-3-甲醛反应得到 1,2-双香豆素乙烯.这些化合物在其富电子二烯组分 C 3-c 4-c 10-c 9 处与缺电子亲二烯体发生区域特异性 Diels-Alder 反应.正常电子需求 Diels-Alder 反应的可行性可以基于 Homo-Lumo 间隙来解释.所有的化合物都是新的并且颜色很深.
DOI:10.1055/s-0031-1290454

专利信息

专利号:US-4287123-A
优先权日:1980-01-14
标题 :Synthesis of thienamycin via (3SR, 4RS)-3-((RS)-1-acyloxyethyl)-2-oxo-4-azetidineacetate
发明人：LIU THOMAS M H; MELILLO DAVID G; RYAN KENNETH M; SHINKAI ICHIRO; SLETZINGER MEYER
权利人:MERCK & CO INC
摘要:Disclosed is a process for the stereocontrolled total synthesis of thienamycin, which synthesis proceeds via intermediate II: II wherein R is a readily removable carboxyl protecting group; and is a readily removable acyl group.

专利号:US-4127608-A
优先权日:1977-05-17
标题 :Synthesis of Vitamin E
发明人：OLSON GARY L; SAUCY GALBRIEL
权利人:HOFFMANN LA ROCHE
摘要:A synthesis of Vitamin E has the condensation of 2,4-pentanediene and 1,2-epoxy-2,6,10,14-tetramethylpentadecane including intermediates in this synthesis which uses base catalyzed condensations of aliphatic compounds to construct the Vitamin E molecule from aliphatic precursors.

专利号:US-4282148-A
优先权日:1980-01-14
标 题:Synthesis of thienamycin via esters of (3SR, 4RS)-3-[(SR)-1-hydroxyethyl]-β,2-dioxo-4-azetidinebutanoic acid
发明人：LIU THOMAS M H; MELILLO DAVID G; RYAN KENNETH M; SHINKAI ICHIRO; SLETZINGER MEYER
权利人:MERCK & CO INC
摘要:Disclosed is a process for the stereocontrolled total synthesis of thienamycin, which synthesis proceeds via intermediate II: II wherein R3 is a readily removable carboxyl protecting group.

专利号:US-4414155-A
优先权日:1980-01-14
标题 :Synthesis of thienamycin via esters of (3SR, 4RS)-3-[(SR)-1-hydroxyethyl]-β,2-dioxo-4-azetidinebutanoic acid
发明人：LIU THOMAS M H; MELILLO DAVID G; RYAN KENNETH M; SHINKAI ICHIRO; SLETZINGER MEYER
权利人:MERCK & CO INC
摘要:Disclosed is a process for the stereocontrolled total synthesis of thienamycin, which synthesis proceeds via intermediate II: II wherein R3 is a readily removable carboxyl protecting group.

专利号:US-4201726-A
优先权日:1977-05-17
标 题 :Synthesis of Vitamin E
发明人：OLSON GARY L; SAUCY GABRIEL
权利人:HOFFMANN LA ROCHE
摘要:A synthesis of Vitamin E has the condensation of 2,4-pentanediene and 1,2-epoxy-2,6,10,14-tetramethylpentadecane including intermediates in this synthesis which uses base catalyzed condensations of aliphatic compounds to construct the Vitamin E molecule from aliphatic precursors.

专利号:US-2025162968-A1
优先权日:2022-02-02
标 题 :Method for Producing Ionizable Lipids or Intermediates for the Synthesis of Such Lipids
发明人：ATMURI N D PRASAD; ARNOLD DEAGLAN; SAADATI FARIBA; KUREK DANIEL; KULKARNI JAYESH; WITZIGMANN DOMINIK; CIUFOLINI MARCO A
权利人:NANOVATION THERAPEUTICS INC
摘要:The present disclosure provides a method for producing one or more intermediates for the synthesis of one or more ionizable lipids, the method comprising: (i) producing a beta-ketoacid by reacting a cyclic ester, a terminal hydroxyester or a derivative thereof, a dicarboxylic acid half ester, or an acid chloride derivative of the dicarboxylic acid half ester, in a condensation reaction, thereby producing the beta-ketoacid or a beta-ketoester that is hydrolyzed to produce the beta-ketoacid; and (ii) decarboxylating the beta-ketoacid, thereby producing the one or more intermediates, wherein the one or more intermediates have a structure that may be defined by Formula A. Further provided is a method for producing ionizable lipid from the intermediate comprising adding an ionizable head group moiety to (a) a ketone group of one or more intermediates having the structure that may be defined by Formula A; or (b) a corresponding alcohol of the intermediate.