专利号:US-4866175-A 优先权日:1966-11-08 标 题 :Novel process for the synthesis of quinoxaline and benzimidazole-N-oxides 发明人:ISSIDORIDES COSTAS H; HADDADIN MAKHLUF J 权利人:RESEARCH CORP 摘要:The synthesis of quinoxaline and benzimidazole-N-oxides and of ester amd amide derivatives of 3-hydroxy-2-quinoxalinecarboxylic acid by a movel process consisting of the reaction between a benzofuroxan and an activated methylene-containing compound under basic conditions.
专利号:US-11926624-B2 优先权日:2018-06-29 标 题:Synthesis of coelenterazine synthesis intermediate 发明人:DUVVURU RAJAGOPALA REDDY 权利人:INT PAPER CO 摘要:Disclosed herein are synthesis methods for coelenterazine and intermediates. Also disclosed are articles including the coelenterazine and coelenterazine derivatives. Representative absorbent articles include disposable diapers and adult incontinence products.
专利号:US-11939332-B2 优先权日:2018-06-29 标题:Synthesis of coelenterazine 发明人:DUVVURU RAJAGOPALA REDDY; BHATT RAMA; KUMAR ANIL 权利人:INT PAPER CO 摘要:Disclosed herein are synthesis methods for coelenterazine. Also disclosed are articles including the coelenterazine and coelenterazine derivatives. Representative absorbent articles include disposable diapers and adult incontinence products.
专利号:US-4005131-A 优先权日:1976-01-02 标 题 :Synthesis of oxalate esters from carbon monoxide and acetals or ketals 发明人:ZEHNER LEE R 权利人:ATLANTIC RICHFIELD CO 摘要:A process for the preparation of oxalate esters by the catalytic oxidative carbonylation of acetals and ketals with carbon monoxide and oxygen-containing gas in the presence of a metal salt catalyst, an amine base and a catalytic amount of an alcohol. Preferably a catalytic amount of particular metal oxidizing salts is employed along with a catalytic amount of an acid or an amine salt compound. Alternatively various counterions and ligands of the metal salt catalysts may be employed.
专利号:US-5470979-A 优先权日:1994-07-01 标 题:Asymmetric synthesis of bicyclic amino acid esters 发明人:TROVA MICHAEL P 权利人:AMERICAN CYANAMID CO 摘要:The invention is an improved process for producing an optically active compound of formula IV: ##STR1## wherein R 1 , R 2 and R 4 are herein described. The improved process to produce a compound of formula IV comprises: n a). reacting a diene with a chiral compound, containing a chiral auxiliary to obtain an olefinic compound; n b). removing the chiral auxiliary and reducing the olefin by hydrogenation to obtain a compound of formula IV.
专利号:US-9181203-B2 优先权日:2010-11-12 标题:Substituted pyrazino[2,3-d]isooxazoles as intermediates for the synthesis of substituted pyrazinecarbonitriles and substituted pyrazinecarboxamides 发明人:NAKAMURA KOUKI; MURAKAMI TAKESHI; NAITOU HIROYUKI; HANAKI NAOYUKI; WATANABE KATSUYUKI 权利人:FUJIFILM CORP; TOYAMA CHEMICAL CO LTD 摘要:The object of the present invention is to provide a compound which is useful as a production intermediate of pyrazine carboxamide derivative such as 6-fluoro-3-hydroxy-2-pyrazine carboxamide. The present invention provides a pyrazino[2,3-d]isoxazole derivative represented by the formula (I): n nwherein X represents a halogen atom, a hydroxyl group or a sulfamoyloxy group, and Y represents —C(â•?O)R or —CN; wherein R represents a hydrogen atom, an alkoxy group an aryloxy group, an alkyl group, an aryl group or an amino group.