CAS: 112-04-9; Octadecyltrichlorosilane

该化合物是有机硅化合物,其特点是长的缺水八十二烷链和三氯替代物附于硅原子,该化合物一般是无色的,可粉色黄色液体,在不同条件下以低挥发性和高稳定性著称,主要用作硅合金剂,加强有机材料粘合到无机基体,在涂层,密封剂和粘合剂中特别有用.八十二烷链的存在具有疏水性,使其在水溶液应用中有效.此外,该化合物的氯化性质允许进一步的化学再活动,使其与各种表面相连接.三氯环十二烷还被用于改变表面,以提高其与有机材料的兼容性,从而增强各种工业应用的性能.在处理该化合物时,应注意安全防范措施,因为其反应性氯原子具有危险性.

结构式图片

欧盟法规

REACH注册ECHA物质ECHA物质C&L通报REACH预注册

上下游产品

CAS号3386-33-2 氯代十八烷 | CAS号112-88-9 1-十八烯 | CAS号10025-78-2 三氯氢硅 | CAS号10026-04-7 四氯化硅 | CAS号112-89-0 溴代十八烷 | CAS号3069-42-9 十八烷基三甲氧基硅烷

合成工艺路线路线简述

  • 合成目标产物 N-Octadecyltrichlorosilane 主要起始原料 1-Chlorooctadecane
  • (文献来源)合成步骤主要原料 1-Chlorooctadecane
1-octadecylmagnesium Bromide置于四氯化硅,乙醚,苯体系中,化学反应生成十八烷基三氯硅烷
参考文献:Alkyl Silicon Chlorides And Their Preparation
标题:Alkyl Silicon Chlorides And Their Preparation

海关参考信息

专利信息


专利号:US-2023313255-A1
优先权日:2020-07-15
标题:Massively Parallel Enzymatic Synthesis of Polynucleotides
发明人:HORGAN ADRIAN; LACHAIZE HENRI; VERARDO DOMIANO; GODRON XAVIER
权利人:DNA SCRIPT
摘要:The invention is directed to methods and compositions for inkjet assisted synthesis of a plurality of polynucleotides at reaction sites on a substrate using template-free polymerases, such as, terminal deoxynucleotidyl transferases (TdTs). Compositions of the invention include formulations of synthesis reagents for inkjet delivery including, but not limited to, TdT coupling reaction buffers and 3′-O-protected dNTP monomers.

专利号:US-2024024489-A1
优先权日:2020-11-20
标 题:Protected disaccharides, their process of preparation and their use in the synthesis of zwitterionic oligosaccharides, and conjugates thereof
发明人:MULARD LAURENCE; DHARA DEBASHIS; PFISTER HELENE; PAOLETTI JULIE; PHALIPON ARMELLE; GUERREIRO-INVERNO CATHERINE
权利人:PASTEUR INSTITUT
摘要:The present invention provides zwitterionic oligosaccharides, in particular fragments of the surface polysaccharides from Shigella sonnei and Shigella sonnei conjugates comprising them. The present invention also provides protected disaccharides, their process of preparation and their use in the synthesis of zwitterionic oligosaccharides, and conjugates thereof, the disaccharide repeating unit of Shigella sonnei being: (I)

专利号:US-2023323449-A1
优先权日:2021-12-17
标 题:Compositions and methods for detection of variants
发明人:GANTT RICHARD; ARNESON ADRIANA
权利人:TWIST BIOSCIENCE CORP
摘要:Testing the many hypotheses from genomics and systems biology experiments demands accurate and cost-effective gene and genome synthesis. Here we describe a microchip-based technology for multiplex gene synthesis. Pools of thousands of ‘construction’ oligonucleotides and tagged complementary ‘selection’ oligonucleotides are synthesized on photo-programmable microfluidic chips, released, amplified and selected by hybridization to reduce synthesis errors ninefold. A one-step polymerase assembly multiplexing reaction assembles these into multiple genes. This technology enabled us to synthesize all 21 genes that encode the proteins of the Escherichia coli 30S ribosomal subunit, and to optimize their translation efficiency in vitro through alteration of codon bias. This is a significant step towards the synthesis of ribosomes in vitro and should have utility for synthetic biology in general.

专利号:US-9981239-B2
优先权日:2015-04-21
标题:Devices and methods for oligonucleic acid library synthesis
发明人:BANYAI WILLIAM; PECK BILL JAMES; FERNANDEZ ANDRES; CHEN SIYUAN; INDERMUHLE PIERRE; MARSH EUGENE P
权利人:TWIST BIOSCIENCE CORP
摘要:Devices and methods for de novo synthesis of large and highly accurate libraries of oligonucleic acids are provided herein. Devices include structures having a main channel and microchannels, where the microchannels have a high surface area to volume ratio. Devices disclosed herein provide for de novo synthesis of oligonucleic acids having a low error rate.

专利号:WO-2024153643-A1
优先权日:2023-01-16
标 题 :Inkjet-assisted enzymatic nucleic acid synthesis
发明人:MOGHADDAM NICOLAS; ADELIZZI BEATRICE; LOMAN TESSA; VERARDO DAMIANO; RODRIGUEZ-PINZON DANIEL; HORGAN ADRIAN
权利人:DNA SCRIPT
摘要:Methods, devices, and compositions are provided for inkjet-assisted synthesis of a plurality of polynucleotides at reaction sites on a substrate using template-free polymerases, such as, terminal deoxynucleotidyl transferases (TdTs). Compositions include printable stabile formulations of synthesis reagents for inkjet delivery including, but not limited to, template-free polymerases, divalent cations, and nucleotides.

专利号:US-11512347-B2
优先权日:2015-09-22
标 题 :Flexible substrates for nucleic acid synthesis
发明人:PECK BILL JAMES
权利人:TWIST BIOSCIENCE CORP
摘要:Provided herein are compositions, devices, systems and methods for the generation and use of biomolecule-based information for storage. Further described herein are highly efficient methods for long term data storage with 100% accuracy in the retention of information. Additionally, devices described herein for de novo synthesis of oligonucleic acids encoding information related to the original source information may have a flexible material for oligonucleic acids extension.
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合成参考文献


参考文献:10.2116/analsci.27.671
摘要:Fukuyama M, Hibara A. Release of Encapsulated Content in Microdroplets. Analytical Sciences. 2011 Jul 10;27(7):671–2. doi: 10.2116/analsci.27.671.
参考文献:10.1166/jnn.2011.3894
摘要:Sakane H, Yoshimatsu A, Shigetoshi T, Uchikoshi J, Morita M, Arima K. Selective adsorption of organosilane molecules along step edges of atomically flattened Si(111) surfaces. J Nanosci Nanotechnol. 2011 Apr;11(4):2962–7. doi: 10.1166/jnn.2011.3894.
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