CAS: 120-94-5; 1-Methylpyrrolidine

上下游产品

CAS号123-75-1 四氢吡咯 | CAS号50-00-0 甲醛 | CAS号3760-54-1 1-甲酰吡咯烷 | CAS号872-50-4 N-甲基吡咯烷酮(NMP) | CAS号109-99-9 四氢呋喃 | CAS号74-89-5 氨基甲烷 | CAS号96-54-8 N-甲基吡咯 | CAS号593-91-9 三甲基铋 | CAS号81879-34-7 1-(3,4-methylen... | CAS号554-15-4 1H-Pyrrole, 2,5... | CAS号367522-96-1 1-丁基-1-甲基吡咯三氟甲磺酸盐 | CAS号52805-36-4 4-苯甲氧基苯甲腈 | CAS号29134-29-0 (1-吡咯)乙腈 | CAS号20297-37-4 1-Methyl-2-pyrr... | CAS号872-50-4 N-甲基吡咯烷酮(NMP) | CAS号7529-17-1 1-methyl-1-oxid... | CAS号19734-35-1 N-(1-甲基-2-吡咯烷)-... | CAS号616-45-5 2-吡咯烷酮 | CAS号40321-44-6 2-氧代-1-吡咯烷甲醛 | CAS号26601-00-3 N,N-dimethylpyr...

烟碱 反应生成1-甲基吡咯烷
参考文献:Pictet,Chemische Berichte,1905,Vol. 38,P. 1951
标题:Pictet,Chemische Berichte,1905,Vol. 38,P. 1951

专利信息

专利号:US-8350031-B2
优先权日:2008-06-02
标 题:Processes for the synthesis of levocetirizine and intermediates for use therein
发明人：RAO DHARMARAJ RAMACHANDRA; KANKAN RAJENDRA NARAYANRAO; GHAGARE MARUTI; CHIKHALIKAR SANDIP VASANT
权利人:CIPLA LTD; RAO DHARMARAJ RAMACHANDRA; KANKAN RAJENDRA NARAYANRAO; GHAGARE MARUTI; CHIKHALIKAR SANDIP VASANT
摘要:The present invention provides a compound of formula (IV) n nwherein R is Cl, Br, NO 2 , OH or OR′, and R′ is alkyl, and its use in the synthesis of levocetirizine, including its use in the synthesis of (−)-1-[(4-chlorophenyl)-phenylmethyl]piperazine, an intermediate useful in the synthesis of levocetirizine. The present invention also provides compounds (II) and (III) which are useful in the synthesis of compound (IV).

专利号:US-9353057-B2
优先权日:2003-12-30
标 题:Synthesis of acyloxyalkyl carbamate prodrugs and intermediates thereof
发明人：GALLOP MARK A; DAI XUEDONG; SCHEUERMAN RANDALL A; RAILLARD STEPHEN P; MANTHATI SURESH K; YAO FENMEI; PHAN THU; LUDWIKOW MARIA; PENG GE; BHAT SEEMA
权利人:XENOPORT INC
摘要:Methods for synthesis of 1-(acyloxy)-alkyl carbamates, particularly, the synthesis of 1-(acyloxy)-alkyl carbamate prodrugs of primary or secondary amine-containing drugs are described. Also described are methods for synthesis of 1-(acyloxy)-alkyl N-hydroxysuccinimidyl carbonates which are useful intermediates in the synthesis of 1-(acyloxy)-alkyl carbamates are also described.

专利号:US-2004242897-A1
优先权日:2002-07-31
标题 :Universal support media for synthesis of oligomeric compounds
发明人：GUZAEV ANDREI P; MANOHARAN MUTHIAH
摘要:Compounds for the synthesis of oligomeric compounds, particularly oligonucleotides and oligonucleotide mimetics, are provided. In addition, methods for functionalizing a support medium with a first monomeric subunit and methods for the synthesis of oligomeric compounds utilizing the novel compounds bound to support media are provided.

专利号:US-2012165520-A1
优先权日:2010-12-23
标题:Process for the synthesis of prodrugs of opioids
发明人：MCGEE PAUL; GARNETT IAN; JUAN E; MANAGE A; CARNIAUX JEAN-FRANCOIS
权利人:MCGEE PAUL; GARNETT IAN; JUAN E; MANAGE A; CARNIAUX JEAN-FRANCOIS
摘要:The present invention provides a process for the synthesis of opioid prodrugs. In particular, the present invention provides a process for the synthesis of opioid prodrugs comprising: treating an opioid, in the form of a salt or a freebase, with a carbonyl synthon to form an activated intermediate and subsequently reacting the activated intermediate with an amine, in the form of a salt or a freebase.

专利号:US-9988364-B1
优先权日:2017-03-21
标题 :Process for synthesis of Eliglustat and intermediate compounds thereof
发明人：LIU YU; YU GUANNENG; ZHENG ZHIGUO
权利人:ZHEJIANG AUSUN PHARMACEUTICAL CO LTD
摘要:The present invention relates to a process for synthesis of Eliglustat and intermediate compounds thereof. In particular, the present invention relates to a process for synthesis of Eliglustat and pharmaceutically acceptable salts thereof, and relates to the intermediate compounds in the process and a process for preparation of the intermediate compounds.

专利号:US-7825244-B2
优先权日:2005-06-10
标题:Intermediates useful in the synthesis of alkylquinoline and alkylquinazoline kinase modulators, and related methods of synthesis
发明人：BAINDUR NAND; GAUL MICHAEL DAVID; KREUTTER KEVIN DOUGLAS; XU GUOZHANG
权利人:JANSSEN PHARMACEUTICA NV
摘要:The invention is directed to alkylquinoline and alkylquinazoline compounds of Formula C: n nwherein R 1 , R 2 , R 99 , and X are as defined herein, the use of such compounds in the synthesis of protein tyrosine kinase inhibitors, particularly inhibitors of FLT3 and/or c-kit and/or TrkB.