CAS: 120923-37-7; Amidosulfuron

该化合物是一种选择性除草剂,主要用于控制各种作物特别是谷物中的宽叶草,属于对氨基酸合成植物至关重要的灭酶酶乙酸酯合成酶(ALS),其特点是其低施用率较高,因此与传统除草剂相比,它是一种环境上有利的选择.氨二硫磷通常用于乳后应用,允许它积极种植杂草,同时尽量减少对作物的伤害.它溶于水,便于其在液体配方中应用.该物质对哺乳动物和鸟类具有相对较低的毒性,尽管可能对水生生物构成危险.其化学结构包括一个全氟辛烷磺酸组,有助于其除草活动.同所有农用化学品一样,妥善处理和遵守安全准则对于减轻任何潜在的环境影响至关重要.

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CAS号53203-08-0 N-methyl-N-sulf... | CAS号89392-03-0 4,6-二甲氧基-2-(苯氧基...

合成工艺路线路线简述

  • 合成目标产物 Amidosulfuron 主要起始原料 Methanesulfonamide, N-(Aminosulfonyl)-N-Methyl- And 4,6-Dimethoxy-2-(Phenoxycarbonyl)Aminopyrimidine
  • (文献来源)合成步骤主要原料 Methanesulfonamide, N-(Aminosulfonyl)-N-Methyl- 和 4,6-Dimethoxy-2-(Phenoxycarbonyl)Aminopyrimidine
Methylsulfonyl-Methylamino-Sulfonamid,4,6-二甲氧基-2-(苯氧基羰基)氨基嘧啶置于乙腈,水体系中,用 乙腈 用作溶剂,化学反应 18.0H,以72.6 G Of The Desired Product Of A Purity Of 98.4% Are Obtained的收率获得酰嘧磺隆
参考文献:Process For The Preparation Of N-Alkylsulfonylaminosulfonylureas
标题:Process For The Preparation Of N-Alkylsulfonylaminosulfonylureas
摘要:公式(i)中已知的除草剂为:##str1## 其中r.Sup.1是烷基,烯烃基或炔基,可选择由卤素,烷氧基或烷氧羰基取代;R.Sup.2是氢,烷基,烯烃基,炔基或环烷基;R.Sup.3和r.Sup.4是氢或烷基;R.Sup.5和r.Sup.6是氢,烷基或烷氧基,每个基都可以由卤素,烷氧基或烷基硫取代,或者是卤素,烷基硫,烷基氨基或二烷基氨基,或者如果r.Sup.2或r.Sup.3是氢,则它们的碱盐可以通过将公式ii的化合物r.Sup.1-So.Sub.2-Nr.Sup.2-So.Sub.2-Nhr.Sup.3(II)与公式iii的化合物反应得到:##str2## 其中r.Sup.4,R.Sup.5和r.Sup.6如上所定义,R.Sup.7是烷基,卤代烷基或可选择取代的苯基,在惰性有机溶剂中,得到公式i的化合物.

海关参考信息

专利信息


专利号:WO-2024256370-A1
优先权日:2023-06-13
标 题 :Synthesis of glufosinate using an amidase-based process
发明人:ZIMMERMANN GUNTHER; POTT MORITZ STEFAN
权利人:BASF SE
摘要:The present invention relates to a method of preparing glufosinate, comprising the steps of hydrolysing an N-carbamoyl glufosinate amide with an Amidase enzyme to form an N- carbamoyl amino acid compound followed by cleaving off the carbamoyl moiety of said N- carbamoyl amino acid compound.

专利号:US-2025120400-A1
优先权日:2021-12-10
标题:Synthesis of glufosinate using a hydantoinase-based process
发明人:DITRICH KLAUS; BREUER MICHAEL; POTT MORITZ STEFAN; ZIMMERMANN GUNTHER; SEEMAYER STEFAN
权利人:BASF SE
摘要:The present invention relates to a method of manufacturing glufosinate, comprising the steps of hydrolysing a hydantoin with a Hydantoinase enzyme to form a N-carbamoyl amino acid compound followed by cleaving off the carbamoyl moiety of said N-carbamoyl amino acid compound.

专利号:WO-2021130756-A1
优先权日:2019-12-25
标题:Combinations of non-protein amino acids and acetolactate synthase enzyme inhibitors
发明人:KLIPCAN LIRON; VAN-OSS PINHASI RUTH
权利人:THE STATE OF ISRAEL MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT AGRICULTURAL RES ORGANIZATION ARO VO
摘要:The present invention provides compositions and methods for disrupting protein synthesis in plant cells.

专利号:US-11919928-B2
优先权日:2016-03-16
标题 :Method for producing dihydrotentoxin
发明人:KUBO TAKASHI; MACHIDA MASAYUKI; FUJIOKA TOMONORI; YAMAGUCHI Shigenari; KAWAI KIYOSHI
权利人:KUMIAI CHEMICAL INDUSTRY CO
摘要:An object of the present invention is to identify an enzyme having activity of synthesizing dihydrotentoxin that is a tentoxin precursor and an enzyme having activity of synthesizing tentoxin using dihydrotentoxin as a substrate. The present invention concerns a tentoxin synthesis-related gene encoding a protein comprising the amino acid sequence of SEQ ID NO: 16 and having activity of nonribosomal peptide synthesis of dihydrotentoxin and a tentoxin synthesis-related gene encoding a protein comprising the amino acid sequence of SEQ ID NO: 18 and having activity of converting dihydrotentoxin to tentoxin.

专利号:US-2021386068-A1
优先权日:2018-11-07
标题 :Compositions comprising pyridine carboxylate herbicides and very long chain fatty acid (vlcfa) synthesis inhibitor herbicides
发明人:KISTER JEREMY; SATCHIVI NORBERT M
权利人:CORTEVA AGRISCIENCE LLC
摘要:Disclosed herein are compositions comprising (a) a pyridine carboxylate herbicide or an agriculturally acceptable N-oxide, salt, or ester thereof and (b) a VLCFA synthesis inhibitor herbicide. Also disclosed herein are methods of controlling undesirable vegetation, comprising applying to vegetation or an area adjacent the vegetation or applying in soil or water to control the emergence or growth of vegetation (a) a pyridine carboxylate herbicide or an agriculturally acceptable N-oxide, salt, or ester thereof, and (b) a VLCFA synthesis inhibitor herbicide.

专利号:US-2021352899-A1
优先权日:2018-11-07
标题 :Compositions comprising pyridine carboxylate herbicides and fatty acid and lipid synthesis inhibitor herbicides
发明人:KISTER JEREMY; SATCHIVI NORBERT M
权利人:CORTEVA AGRISCIENCE LLC
摘要:Disclosed herein are compositions comprising (a) a pyridine carboxylate herbicide or an agriculturally acceptable N-oxide, salt, or ester thereof and (b) a fatty acid and lipid synthesis inhibitor (FA/LSI) herbicide, an agriculturally acceptable salt or ester thereof, or mixtures thereof. Also disclosed herein are methods of controlling undesirable vegetation, comprising applying to vegetation or an area adjacent the vegetation or applying in soil or water to control the emergence or growth of vegetation (a) a pyridine carboxylate herbicide or an agriculturally acceptable N-oxide, salt, or ester thereof and (b) a fatty acid and lipid synthesis inhibitor (FA/LSI) herbicide, an agriculturally acceptable salt or ester thereof, or mixtures thereof.
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主要参考文献


1: Liu XQ, Yu CY, Dong JG, Hu SW, Xu AX. Acetolactate Synthase-Inhibiting Gametocide Amidosulfuron Causes Chloroplast Destruction, Tissue Autophagy, and Elevation of Ethylene Release in Rapeseed. Front Plant Sci. 2017 Sep 21;8:1625. doi: 10.3389/fpls.2017.01625.
2: Benzi M, Robotti E, Gianotti V. Study on the photodegradation of amidosulfuron in aqueous solutions by LC-MS/MS. Environ Sci Pollut Res Int. 2013 Dec;20(12):9034-43. doi: 10.1007/s11356-013-1900-x. Epub 2013 Jun 16. 71(13):5117-5126. doi: 10.1021/acs.jafc.2c08528. Epub 2023 Mar 21. 579(2):146-51. doi: 10.1016/j.aca.2006.07.034. Epub 2006 Jul 22. 69(6):717-21. doi: 10.1002/ps.3427. Epub 2012 Nov 9.
170:234-41. doi: 10.1016/j.saa.2016.07.025. Epub 2016 Jul 15. 61(22):5271-8. doi: 10.1021/jf400133w. Epub 2013 May 22. 186(8):486. doi: 10.1007/s00604-019-3536-0.

合成参考文献


参考文献:10.1107/s1600536810024785
摘要:Fun HK, Goh JH, Rai S, Isloor AM, Shetty P. Methyl 2,6-bis-[(5-chloro-4,6-dimeth-oxy-pyrimidin-2-yl)-oxy]benzoate. Acta Crystallogr Sect E Struct Rep Online. 2010 Jun 30;66(Pt 7):o1869–70.
参考文献:10.1107/s1600536810024724
摘要:Fun HK, Goh JH, Rai S, Isloor AM, Shetty P. Methyl 2,6-bis-[(5-bromo-4,6-dimeth-oxy-pyrimidin-2-yl)-oxy]benzoate. Acta Crystallogr Sect E Struct Rep Online. 2010 Jun 30;66(Pt 7):o1871.
参考文献:10.1107/s1600536810025067
摘要:Fun HK, Yeap CS, Rai S, Isloor AM, Shetty P. 4,6-Dimeth-oxy-2-(methyl-sulfon-yl)pyrimidine. Acta Crystallogr Sect E Struct Rep Online. 2010 Jul 03;66(Pt 8):o1913.
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