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CAS号1224637-01-7 1-ethylpyrrolid... | CAS号2167-11-5 3-氯-1-乙基哌啶 | CAS号64-17-5 乙醇 | CAS号27822-68-0 1-[2-(羟基甲基)-1-吡咯烷]乙酮 | CAS号54385-06-7 1-acetyl-2-chlo... | CAS号498-63-5 吡咯烷-2-甲醇 | CAS号87-69-4 酒石酸 | CAS号57826-83-2 6-chloro-3,5-di... | CAS号57796-49-3 5-benzylamino-6... | CAS号57796-50-6 5-allylamino-6-... | CAS号71675-85-9 阿米舒必利 | CAS号15676-16-1 舒必利 | CAS号71675-94-0 4-amino-N-[(1-e... | CAS号71676-00-1 S-去乙基S-甲基氨磺化物 | CAS号72412-36-3 2-(2-Amino-4-me... | CAS号72412-52-3 N-((1-Ethyl-2-p... | CAS号72418-31-6 2-amino-N-[(1-e... | CAS号65515-22-2 N-[(1-ethylpyrr... | CAS号68256-07-5 N-[(1-ethylpyrr... | CAS号68256-25-7 4-chloro-N-[(1-...合成工艺路线路线简述
- 合成目标产物 2-(Aminomethyl)-1-Ethylpyrrolidine 主要起始原料 1-Ethyl-1H-Pyrrole-2-Carbaldehyde
- (文献来源)合成步骤主要原料 1-Ethyl-1H-Pyrrole-2-Carbaldehyde
酒石酸 反应生成N-乙基-2-氨甲基吡咯烷
参考文献:Organic Compounds And Their Use As Pharmaceuticals
标题:Organic Compounds And Their Use As Pharmaceuticals
摘要:一种具有以下结构的药物化合物 ##str1## 其中r.Sup.1为--Cho,Ch.Sub.2 Oh,--Ch.Sub.2 oc.Sub.1-4烷基,--Coc.Sub.1-3烷基,--Ch(Oh)C.Sub.1-3烷基或--Cooh,R.Sup.2为c.Sub.1-4烷基,--Cho,--Ch.Sub.2 Oh,--Ch.Sub.2 oc.Sub.1-4烷基,--Coc.Sub.1-3烷基,--Ch(Oh)C.Sub.1-3烷基或--Cooh,R.Sup.3为c.Sub.1-4烷基,X为吡咯啉基或吡咯啉甲基;及其盐和酯.
专利信息
专利号:US-5468876-A
优先权日:1986-05-22
标题:Intermediates for the stereoconservative synthesis of 1-substituted (S)-and (R)-2-aminomethylpyrrolidines
发明人:FEDERSEL HANS-JUEGEN; HOE THOMAS; RAEMSBY STEN I; STROEM PETER H E
权利人:ASTRA AB
摘要:Disclosed are (R)- and (S)-isomers of the compounds of the Formulas II and III with at least 95% optical purity ##STR1## wherein R 1 and R 2 are the same or different and represent a hydrogen atom, a lower alkyl, lower alkenyl or lower alkynyl group, a cycloalkyl group or a group (CH 2 ) m Ph, wherein m is 0-3 and Ph is a substituted or unsubstituted phenyl group. n These compounds are intermediates in the stereoconservative synthesis of 1-substituted (S)- and (R)-2-aminomethylpyrrolidines.
专利号:US-5174981-A
优先权日:1991-10-04
标题 :Synthesis of crystalline ZSM-5-type material
发明人:HELLRING STUART D; STRIEBEL RANDY F
权利人:MOBIL OIL CORP
摘要:This invention relates to a new form of crystalline material identified as zeolite ZSM-5-type, to a new and useful method for synthesizing said crystalline material and to use of said crystalline material prepared in accordance herewith as a catalyst for organic compound, e.g. hydrocarbon compound, conversion.
专利号:US-7468375-B2
优先权日:2004-04-26
标题:Inhibitors of the HIV integrase enzyme
发明人:DRESS KLAUS RUPRECHT; HU QIYUE; JOHNSON TED WILLIAM; PLEWE MICHAEL BRUNO; TANIS STEVEN PAUL; WANG HAI; YANG ANLE; YIN CHUNFENG; ZHANG JUNHU
权利人:PFIZER
摘要:The present invention is directed to compounds of formula (I), and pharmaceutically acceptable salts and solvates thereof, their synthesis, and their use as modulators or inhibitors of the human immunodeficiency virus (“HIVâ€?) integrase enzyme.
专利号:WO-8707271-A1
优先权日:1986-05-22
标 题 :A stereoconservative synthesis of 1-substituted (s)- and (r)-2-aminomethylpyrrolidines and intermediates thereto
专利号:US-2025259704-A1
优先权日:2022-06-24
标 题:Systems and methods for cell-free iterative site saturation mutagenesis and its application for the directed evolution of enzymes catalyzing unnatural reactions
发明人:JEWETT MICAHEL C; BOGART JONATHAN W; LANDWEHR GRANT M; Karim Ashty Stephen
权利人:UNIV NORTHWESTERN
摘要:Disclosed are methods, compositions, systems, and protein compounds for the directed evolution of enzymes and proteins. The method comprising generating variant protein with a desired functionality, comprising one or more DNA expression templates comprising nucleic acid sequences encoding a variant protein, expressing the variant protein using cell-free protein synthesis; and analyzing one or more parameters associated with the variant protein.
专利号:US-6417195-B1
优先权日:1999-02-22
标题 :Isoquinoline derivatives and isoquinoline combinatorial libraries
发明人:LEBL MICHAL
权利人:LION BIOSCIENCE AG
摘要:The present invention provides the synthesis of heterocyclic compounds based on the isoquinoline ring. More specifically, the invention provides novel isoquinoline derivatives as well as novel libraries comprised of such compounds.