专利号:US-5849936-A 优先权日:1995-03-15 标题:Method for the synthesis of bis-tetrahydrofuranyl annonaceous acetogenins 发明人:HOYE THOMAS R; TAN LUSHI 权利人:UNIVERISTY OF MINNESOTA 摘要:A method for the synthesis of bis-tetrahydrofranyl Annonaceous acetogenins, including the natural products and analogs thereof, is provided which proceeds by the Pd-mediated coupling of a bis-tetrahydrofuranyl-subunit comprising a terminal alkyne, with a (C4)-hydroxybutenolide subunit comprising a terminal vinyl iodide, followed by selective reduction of the resulting enyne.
专利号:WO-2024151344-A9 优先权日:2022-11-18 标题:A device that enables the combinatorial synthesis of small molecule libraries 发明人:COPELAND Gregory; LIU JANE 权利人:BRT BIOTECHNOLOGIES INC 摘要:A device for the synthesis of small molecules on a substrate is provided. The device includes a synthesis plate with vias, and a microfluidic patterning plate with a series ot open-faced channels that can be aligned with the vias on the synthesis plate. The device may be used to synthesize combinatorial libraries of small molecules.
专利号:US-2021107859-A1 优先权日:2018-04-06 标题 :A process for the synthesis of carbon labeled organic compounds 发明人:AUDISIO DAVIDE; CANTAT THIBAULT; DESTRO GIANLUCA 权利人:COMMISSARIAT ENERGIE ATOMIQUE 摘要:A process for the synthesis of a carbon labeled organic compound containing a carbon labeled carboxyl group is described. A method of using carbon labeled organic compounds containing a carbon labeled carboxyl group according to the present disclosure; a process for manufacturing labeled pharmaceuticals and agrochemicals comprising synthesis of carbon labeled organic compounds containing a carbon labeled carboxyl group according to the present disclosure; and a process for producing tracers comprising synthesis of carbon labeled organic compounds containing a carbon labeled carboxyl group according to the present disclosure are also described.
专利号:US-2025236694-A1 优先权日:2024-01-19 标 题:Synthesis of highly branched polymers via high throughput screening 发明人:XU MIZHI; IWASO KAZUHISA; SHANNON DECLAN; BATES MORGAN W; WANG HENGBIN; CHATANI SHUNSUKE; HAWKER CRAIG J 权利人:UNIV CALIFORNIA; THE MITSUBISHI CHEMICAL CORP 摘要:Efficient condition optimization for the synthesis of highly branched polymers using high throughput screening has been developed. This innovation allows rapid production of soluble, highly branched polymers with different properties (molecular weight, degree of branching, etc.). Moreover, this versatile technique has the potential to be extended to other monomer/linker systems and polymerization techniques such as emulsion or suspension polymerization, anionic polymerization and continuous flow synthesis. A resin composition is further disclosed.
专利号:US-8293930-B1 优先权日:2004-06-25 标题 :One pot synthesis of taxane derivatives and their conversion to paclitaxel and docetaxel 发明人:NAIDU RAGINA 权利人:NAIDU RAGINA; CHATHAM BIOTEC LTD 摘要:A process is provided for the semi-synthesis of taxane intermediates useful in the preparation of paclitaxel and docetaxel, in particular, the semi-synthesis of protected taxane intermediate in a one pot reaction of protecting the C-7 and C-10 positions and attaching a side chain at the C-13 position and subsequently deprotecting the group to form paclitaxel or docetaxel, and taxane intermediates.
专利号:US-7893283-B2 优先权日:2004-06-04 标题:Semi-synthesis of taxane intermediates and their conversion to paclitaxel and docetaxel 发明人:NAIDU RAGINA 权利人:CHATHAM BIOTEC LTD 摘要:A process is provided for the semi-synthesis of taxane intermediates useful in the preparation of paclitaxel and docetaxel, in particular, the semi-synthesis of protected taxane intermediates.
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