CAS: 6609-56-9; 2-Methoxybenzonitrile

上下游产品

CAS号29577-53-5 2-甲氧基苯甲醛肟 | CAS号6850-57-3 2-甲氧基苄胺 | CAS号2439-77-2 2-甲氧基苯甲酰胺 | CAS号100-66-3 苯甲醚 | CAS号68-12-2 N,N-二甲基甲酰胺 | CAS号135-02-4 邻甲氧基苯甲醛 | CAS号529-28-2 邻碘苯甲醚 | CAS号57-13-6 尿素 | CAS号578-57-4 邻溴苯甲醚 | CAS号557-21-1 氰化锌 | CAS号35276-83-6 2-甲氧基苯甲酰乙腈 | CAS号57598-33-1 2-(2-甲氧基苯基)-4,4... | CAS号42590-97-6 2-甲氧基苯硫代甲酰胺 | CAS号51449-81-1 5-(2-甲氧基苯基)-1H-四唑 | CAS号22233-80-3 Hydrazinecarbox... | CAS号611-20-1 水杨腈 | CAS号34557-54-5 methane | CAS号579-75-9 邻甲氧基苯甲酸 | CAS号2439-77-2 2-甲氧基苯甲酰胺 | CAS号883899-02-3 2-氰基-3-甲氧基苯硼酸新戊二醇酯

邻甲氧基苯甲醛置于dichloro[1,3-Bis(2-Methylphenyl)-2-Imidazolidinylidene](Benzylidene) (Tricyclohexylphosphine) Ruthenium(II),Ammonium Acetate,氧气体系中,用 5,5-Dimethyl-1,3-Cyclohexadiene 作为反应溶剂,130.0 °C,101.33 Kpa 条件下,反应 1.5H,以80%的收率获得产物2-甲氧基苯甲腈
参考文献:有氧氧化伯胺和原位反应生成的胺与格鲁布斯催化剂从醛和铵盐中合成腈
标题:有氧氧化伯胺和原位反应生成的胺与格鲁布斯催化剂从醛和铵盐中合成腈
摘要:本文报道了格鲁布斯催化的伯胺的需氧氧化合成腈的路线.该反应可容纳多种底物,包括简单的伯胺,空间受阻的β,β-二取代胺,烯丙胺,苄胺和α-氨基酯.还指出了与各种官能团的反应相容性,特别是与烯烃,炔烃,卤素,酯,甲硅烷基醚和游离羟基的相容性.腈也是通过醛和nh 4 Oac原位反应生成的亚胺氧化合成的.
DOI:10.1002/adsc.202000663

专利信息

专利号:WO-2023237381-A1
优先权日:2022-06-09
标题:Process for the synthesis of polyethylenes or copolymers of ethylene and 1,3-diene having a terminal ketone function
发明人：BOISSON CHRISTOPHE; D'AGOSTO FRANCK; DESGRANGES ARIANE; NGO ROBERT; JEAN-BAPTISTE-DIT-DOMINIQUE FRANÇOIS
权利人:MICHELIN & CIE; CENTRE NAT RECH SCIENT; ECOLE SUPERIEURE DE CHIMIE PHYSIQUE ELECTRONIQUE LYON; UNIV CLAUDE BERNARD LYON
摘要:The invention relates to a method for preparing a polyethylene having a terminal ketone function or a copolymer of ethylene and a 1,3-diene and optionally a vinyl aromatic compound which contains more than 50 mol% of ethylene and has a terminal ketone function; said method comprises a polymerization reaction of the monomers in the presence of a borohydrido-neodymocene complex and an organo-magnesium compound, followed by a coupling reaction with a compound having a nitrile function, and then a hydrolysis reaction.

专利号:US-4536599-A
优先权日:1978-08-22
标题:Synthesis of amine derivatives
发明人：MASUKO FUJIO; KATSURA TADASHI
权利人:SUMITOMO CHEMICAL CO
摘要:An amine of the formula, ##STR1## wherein R 1 , R 2 , R 3 , R 4 and R 5 are each hydrogen, alkyl or the like and n is 1, 2 or 3, including α-phenyl-β-(p-tolyl)-ethylamine, which is useful as an optically resolving agent, an intermediate of medicines and the like, is effectively produced by a novel process comprising hydrolysis of the corresponding nitrile of the formula, ##STR2## wherein R 1 , R 2 , R 3 , R 4 , R 5 and n are the same as above, followed by alkali-decomposition of the resulting amide of the formula, ##STR3## wherein R 1 , R 2 , R 3 , R 4 , R 5 and n are the same as above. An amide including the above one is effectively produced by hydrolysis of the corresponding nitrile in the presence of a base and hydrogen peroxide using an organic quaternary ammonium salt and/or a tertiary amine as a catalyst.

专利号:US-10226449-B2
优先权日:2013-12-20
标 题:Heterocyclic modulators of lipid synthesis and combinations thereof
发明人：HEUER TIMOTHY SEAN; OSLOB JOHAN D; MCDOWELL ROBERT S; JOHNSON RUSSELL; YANG HANBIAO; EVANCHIK MARC; ZAHARIA CRISTIANA A; CAI HAIYING; HU LILY W; DUKE GREGORY; OHOL-GUPTA YAMINI; O'FARRELL MARIE
权利人:3 V BIOSCIENCES INC
摘要:Heterocyclic modulators of lipid synthesis are provided as well as pharmaceutically acceptable salts thereof; pharmaceutical compositions comprising such compounds; and methods of treating conditions characterized by dysregulation of a fatty acid synthase pathway by the administration of such compounds and combinations of such compounds and other therapeutic agents.

专利号:US-7238823-B2
优先权日:2005-06-30
标 题 :Platinum complexes with mononitrile-containing ligands
发明人：XIAO ZEJUN; HAUSHEER FREDERICK H; PETLURU PAVANKUMAR
权利人:BIONUMERIK PHARMACEUTICALS INC
摘要:Disclosed herein are novel platinum-based complexes possessing one nitrile substituent group (mononitrile) covalently-bonded to the platinum, one or more nitrogen donor ligands capable of forming hydrogen bonds with the bases in DNA or RNA and leaving groups (i.e., L 1 and L 2 ) which can be hydrolyzed in vivo to active species, which can then form coordinate adducts with DNA or RNA at the Guanine or Adenine bases thereof. Also disclosed herein are the reaction schemes for the synthesis of said platinum complexes, as well as methods of treatment of various types of cancer by the administration of a pharmaceutically-effective dose of said novel platinum complexes.

专利号:US-3953604-A
优先权日:1972-01-14
标 题:1-(2-Substituted-chromonyloxy)-2-hydroxy-3-(substituted phenoxy)propanes
发明人：WARREN BRIAN THOMAS; SPICER JOHN WILLIAM
权利人:MILES LAB
摘要:Definitions: in the following Formulae I, II and IV, R 1 represents hydrogen, alkyl of 1 to 4 carbon atoms, or a nontoxic cation, while each of R 2 , R 3 , R 4 , R 5 , and R 6 symbolizes hydrogen, alkyl of 1 to 4 carbon atoms, alkoxy of 1 to 4 carbon atoms, carboxy, carbalkoxy of 1 to 4 carbon atoms, trihalomethyl, halogen, nitro or cyano. n Certain 1-(2-substituted-chromon-yloxy)-2-hydroxy-3-(substituted-phenoxy)propanes (Formula I), ##SPC1## n can be synthesized from intermediate bis-(substituted-phenoxy)propanes (Formula II), ##SPC2## n by condensation with diethyl oxalate in the presence of sodium ethoxide followed by cyclization with a mixture of glacial acetic acid and concentrated sulfuric or a mixture of concentrated hydrochloric acid and a lower alcohol containing up to 4 carbon atoms. n The bis-(substituted-phenoxy)propane intermediates (Formula II) are prepared by reacting a dihydroxyacetophenone (Formula III), ##SPC3## n with a (substituted-phenyl)glycidyl ether (Formula IV), ##SPC4## n in an organic solvent in the presence of a catalyst. n The 1-(2-substituted-chromon-yloxy)-2-hydroxy-3-(substituted-phenoxy)propanes (Formula I) are useful in the treatment of allergic conditions in mammals. The bis-(substituted-phenoxy)propanes (Formula II) are useful as intermediates in the synthesis of the latter compounds. Methods of preparing compounds having Formulae I and II are described. Methods of treating allergic conditions in mammals utilizing compounds of Formula I are also disclosed.

专利号:CN-119343386-A
优先权日:2022-06-09
标 题:Synthesis of polyethylene or copolymer of ethylene and 1, 3-diene having terminal ketone function