CAS: 751-94-0; Sodium (Z)-2-((3R,4S,5S,8S,9S,10S,11R,13R,14S,16S)-16-Acetoxy-3,11-Dihydroxy-4,8,10,14-Tetramethyldodecahydro-1H-Cyclopenta[a]Phenanthren-17(2H,10H,14H)-Ylidene)-6-Methylhept-5-Enoate

专利信息

专利号:US-2024197774-A1
优先权日:2021-04-16
标 题:Synthesis of Antimicrobial PVP-coated Bismuth Nanoparticles
发明人：LOPEZ-RIBOT JOSE; VAZQUEZ-MUNOZ ROBERTO
权利人:UNIV TEXAS
摘要:Described herein is a facile, fast, and economical method for the synthesis of BAL-mediated PVP-BiNPs, using basic laboratory instruments and reagents readily available in most laboratories.

专利号:US-2023288116-A1
优先权日:2022-03-14
标 题:Large scale synthesis of pharmaceutical and biologic formulations using thin film freezing
发明人：OWENS III DONALD E; KOLENG JR JOHN J
权利人:TFF PHARMACEUTICALS INC
摘要:The invention encompasses methods for the large-scale (preferably under cGMP or cGLP standards) preparation of micron-sized or submicron-sized particles including pharmaceutical or biologic active agents. The systems and methods include a cryogenic cooling system including a novel shroud that enhances the cooling effects thereby reducing product loss and increasing product yields.

专利号:US-9693999-B2
优先权日:2011-01-26
标题:Small molecule RNase inhibitors and methods of use
发明人：DUNMAN PAUL M; OLSON PATRICK D; CHILDERS WAYNE
权利人:UNIV ROCHESTER; UNIV NEBRASKA; Temple University—Of the Commonwealth System of Higher Education
摘要:Small molecule inhibitors of bacterial ribonuclease (e.g., RnpA) and methods for their synthesis and use are described herein. The methods of using the compounds include treating and preventing microbial infections and inhibiting bacterial ribonuclease. Also described herein are methods of identifying compounds for treating or preventing a microbial infection.

专利号:SA-02230453-B1
优先权日:2001-09-07
标 题 :Methods for the synthesis of conjugate products of an insulin polypeptide with an oligomer, and conjugate products of a proinsulin polypeptide with an oligomer (and methods for their synthesis)

专利号:US-6018042-A
优先权日:1994-08-09
标题:Antitumor antisense oligonucleotides
发明人：METT HELMUT; HAENER ROBERT; DEAN NICHOLAS MARK
权利人:NOVARTIS AG
摘要:The invention relates to deoxyribo- and ribo-oligonucleotides and derivatives thereof, as well as pharmaceutical preparations, therapies, diagnostics and commercial research reagents in relation to disease states which respond to modulation of the synthesis of the enzyme S-adenosylmethionine decarboxylase (SAMDC). In particular, the invention relates to antisense oligonucleotides and oligonucleotide derivatives specifically hybridizable with nucleic acids relating to (preferably human) SAMDC. These oligonucleotides and their derivatives have been found to modulate the synthesis of SAMDC in cells.

专利号:US-2007123467-A1
优先权日:2003-11-13
标 题:Amniotic-derived peptide and uses thereof
发明人：BAKHUTASHVILI VLADIMER; HALLER JORDAN D; BAKHUTASHVILI IVANE; BAKHUTASHVILI ALEXANDER; NICOLETTI FERDINANDO; THIRY MICHAEL; PONCIN ALAIN
权利人:BAKHUTASHVILI VLADIMER; HALLER JORDAN D; BAKHUTASHVILI IVANE; BAKHUTASHVILI ALEXANDER; NICOLETTI FERDINANDO; THIRY MICHAEL; PONCIN ALAIN
摘要:The present invention relates to the method(s) of synthesis of and the therapeutic and cosmetic applications of biologically active peptides for improving the appearance of skin, for hastening wound healing and for treating and/or preventing the progression of various conditions, injuries and diseases, including but not limited to viral hepatitis B and C, herpes zoster ganglioneuritis, diabetic peripheral polyneuropathy, nephrotic syndrome, juvenile rheumatoid arthritis, rheumatoid arthritis, psoriatic arthritis, bronchial asthma, respiratory infection, breast cancer, epilepsy, psoriasis, atherosclerosis and other forms of vascular obstructions, myocardial infarction, HIV and SARS infection, brain cell malfunction due to ischemia and trauma, pathologic consequences of ischemia-reperfusion, rejection reaction following organ transplantation, chemical and drug intoxication including but not limited to anesthetic, alcohol and morphine, cancer, type 1 diabetes mellitus, multiple sclerosis, septic shock (Gram negative sepsis), Parkinson's disease, type 2 diabetes mellitus, Alzheimer's disease, amyotrophic lateral sclerosis, hyperthyroidism, Guillain-Barre syndrome, systematic lupus erythematosus, parasitic infections, especially leishmaniasis, and other collagen diseases, and diseases in which apoptosis occurs.