CAS: 101-98-4; 2-(Benzyl(Methyl)Amino)Ethanol

相似化合物

104-63-2 105496-31-9 26690-80-2

上下游产品

oxirane benzyl-methyl-amine 2-chloro-ethanol formaldehydbenzyl-methyl-vinyl-amine propionitrile3-2-(N-benzyl-N-methylamino)ethoxypropionitrile acetoacetic acid [2-(N-methyl-N-benzylamino)-ethyl]-ester α-Aethoxy-diphenylessigsaeure-2-(benzyl-methyl-amino)-aethylester

2,2'-(苄基亚氨基)二乙醇置于氨,Potassium Amide体系中,用 乙醚 用作溶剂,化学反应生成N-甲基-N-羟乙基苄胺
参考文献:Ortho Substitution Rearrangement Vs. β-Elimination Of Quaternary Ammonium Ion-Alcohols And Methyl Ether With Excess Sodium Amide1
标题:Ortho Substitution Rearrangement Vs. β-Elimination Of Quaternary Ammonium Ion-Alcohols And Methyl Ether With Excess Sodium Amide1
摘要:
Doi:10.1021/jo01050A029

专利信息

专利号:US-2024262834-A1
优先权日:2021-05-28
标 题:Synthesis of btk inhibitor and intermediates thereof
发明人：CHEN YONGGANG; CORRY JAMES; DESMOND RICHARD; DI MASO MICHAEL J; FORSTATER JACOB H; KUETHE JEFFREY T; KUHL NADINE; LARSON REED; LEVESQUE FRANCOIS; NARSIMHAN KARTHIK; OTTE DOUGLAS; PRIER CHRISTOPHER K; SHEVLIN MICHAEL; SIROTA ERIC; TAN LUSHI; THAISRIVONGS DAVID A; TURNBULL BEN W H; WANG ZHIXUN; XIAO KAIJIONG
权利人:MERCK SHARP & DOHME LLC
摘要:The present invention relates to efficient synthetic processes useful in the preparation of Compound A, a BTK inhibitor of Formula (I): or a pharmaceutically acceptable salt thereof, including the preparation of intermediates used to make Compound A or a pharmaceutically acceptable salt thereof.

专利号:US-2024198316-A1
优先权日:2021-05-31
标题 :Synthetic polymeric porous medium with hierarchical multiple layer structure, its design, synthesis, modification, and liquid chromatographic applications
发明人：MAO HUIMING; XU FENG; YANG KE; HU XINMEI; HUANG XUEYING
权利人:SUZHOU SEPAX TECH INC
摘要:A synthetic polymeric porous medium with a core-shell(s) hierarchical layer structure and has an essentially homogeneous porous structure from inside to outside of the medium, whose core and shell(s) are covalently modified with distinct chemical functional groups or same functional group with different density. Here the methodologies for resin syntheses and core-shell(s) modifications and liquid chromatographic applications of the newly developed resins in the field of analysis and purification of Tween surfactants, virus-like particles (VLP)/vaccines/viral vectors/viruses, antibody, and mRNA are disclosed.

专利号:US-9035061-B2
优先权日:2010-07-13
标题:Process for preparing a biphenyl-2-ylcarbamic acid
发明人：COLSON PIERRE-JEAN
权利人:COLSON PIERRE-JEAN; THERAVANCE BIOPHARMA R & D IP LLC
摘要:The invention provides a process of preparing an intermediate useful in the synthesis of biphenyl-2-ylcarbamic acid 1-(2-{[4-(4-carbamoylpiperidin-1-ylmethyl)benzoyl]methylamino}ethyl)piperidin-4-yl ester, and a process of preparing a crystalline freebase of the ester.

专利号:AU-2022280865-A1
优先权日:2021-05-28
标 题 :Synthesis of btk inhibitor and intermediates thereof

专利号:WO-2022252071-A1
优先权日:2021-05-31
标题:A synthetic polymeric porous medium with hierarchical multiple layer structure, its design, synthesis, modification, and liquid chromatographic applications
发明人：MAO HUIMING; XU FENG; YANG KE; HU XINMEI; HUANG XUEYING
权利人:SUZHOU SEPAX TECH INC; SEPAX TECH INC
摘要:A synthetic polymeric porous medium with a core-shell (s) hierarchical layer structure, whose core and shell (s) are covalently modified with distinct chemical functional groups or same functional group with different density. Here the methodologies for resin syntheses and core-shell (s) modifications and liquid chromatographic applications of the newly developed resins in the field of analysis and purification of Tween surfactants, virus-like particles (VLP) /vaccines/viral vectors/viruses, antibody, and mRNA are disclosed.

专利号:WO-2022251404-A1
优先权日:2021-05-28
标 题:Synthesis of btk inhibitor and intermediates thereof