CAS: 13726-67-5; Boc-Asp-Oh

相似化合物

1152-61-0 119062-05-4 136083-57-3

上下游产品

CAS号56-84-8 L-天门冬氨酸 | CAS号24424-99-5 二碳酸二叔丁酯 | CAS号7536-58-5 B°C-L-天冬氨酸 4-苄酯 | CAS号98015-52-2 tert-butyl 1,2,... | CAS号73821-95-1 B°C-L-天冬氨酸4-环己酯 | CAS号75844-68-7 TERT-BUTYL 2,3-... | CAS号5269-42-1 L-Aspartic acid... | CAS号1070-19-5 Carbonazidic ac... | CAS号214630-04-3 B°C-D-天冬氨酸α-9-芴基甲基酯 | CAS号56-84-8 L-天门冬氨酸 | CAS号554-68-7 三乙胺盐酸盐 | CAS号2387-23-7 N,N’-二环己基脲 | CAS号167082-77-1 B°C-Asp-[Asp-(O... | CAS号83345-44-2 (S)-3-((叔丁氧基羰基)... | CAS号30925-18-9 B°C-L-天冬氨酸1-苄酯 | CAS号104227-71-6 (S)-B°C-3-氨基-Y-丁内酯 | CAS号128427-10-1 (S)-2-B°C-氨基-1,4-丁醇 | CAS号2791-79-9 L-天冬氨酸二苄酯

Boc-L-天冬氨酸-4-环己酯置于magnesium,Hydrazinium Monoformate体系中,用 甲醇 用作溶剂,化学反应 2.0H,以93%的收率获得boc-L-天冬氨酸
参考文献:镁/肼基甲酸酯:一种新的氢化方法,用于去除肽合成中一些常用的保护基
标题:镁/肼基甲酸酯:一种新的氢化方法,用于去除肽合成中一些常用的保护基
摘要:描述了通过使用一甲酸肼盐和镁的催化转移氢化除去肽合成中一些常用的保护基.在解封肽合成中大多数常用的保护基团方面,该方法与其他方法具有同等竞争力.在这些条件下,叔丁基衍生的和不稳定的碱保护基团是完全稳定的.Mg / Nh 2-Nh 2 .hcooh的使用使它成为钯的快速,低成本替代品,并将后处理减少为简单的萃取操作.
Doi:10.1016/s0040-4039(01)02113-X

专利信息

专利号:US-2009111737-A1
优先权日:1999-05-24
标题:Novel antibacterial agents
发明人：CHRISTENSEN BURTON G; MORAN EDMUND J; GRIFFIN JOHN H; JUDICE J KEVIN; MU YONGQI; PACE JOHN L; MAMMEN MATHAI; AGGEN JAMES
权利人:CHRISTENSEN BURTON G; MORAN EDMUND J; GRIFFIN JOHN H; JUDICE J KEVIN; MU YONGQI; PACE JOHN L; MAMMEN MATHAI; AGGEN JAMES
摘要:This invention relates to novel multibinding compounds (agents) that are antibacterial agents. The multibinding compounds of the invention comprise from 2-10 ligands covalently connected by a linker or linkers, wherein each of said ligands in their monovalent (i.e., unlinked) state have the ability to bind to a an enzyme involved in cell wall biosynthesis and metabolism, a precursor used in the synthesis of the bacterial cell wall and/or the bacterial cell surface thereby interfere with the synthesis and/or metabolism of the cell wall. In particular the multibinding compounds of the invention comprise from 2-10 ligands covalently connected by a linker or linkers, wherein each of said ligands hasn a ligand domain capable of binding to penicillin binding proteins, a transpeptidase enzyme, a substrate of a transpeptidase enzyme, a beta-lactamase enzyme, pencillinase enzyme, cephalosporinase enzyme, a transglycoslase enzyme, or a transglycosylase enzyme substrate; Preferably, the ligands are selected from the beta lactam or glycopeptide class of antibacterial agents.

专利号:CN-111164071-A
优先权日:2017-09-28
标 题:Process for the preparation of intermediate compounds for the synthesis of medicaments

专利号:CN-1202131-C
优先权日:2003-03-24
标题:One-pot liquid-phase synthesis of thymopentin

专利号:CN-1442428-A
优先权日:2003-03-24
标 题:One-pot liquid-phase synthesis of thymopentin

专利号:US-5616788-A
优先权日:1995-02-15
标 题 :N.sub.α -2-(4-Nitrophenylsulfonyl) ethoxycarbonyl-amino acids
发明人：SAMUKOV VLADIMIR V; SABIROV AYDAR N; POZDNYAKOV PAVEL I
权利人:HYUNDAI PHARM IND CO LTD
摘要:Protected amino acid derivatives of the general formula ##STR1## wherein R 1 represents hydrogen atom, and R 2 represents hydrogen, methyl, isopropyl, 1-methylpropyl, 2-methylpropyl, tert-butoxymethyl, 1-tert-butoxyethyl, 2-methylthioethyl, benzyl, carboxamidomethyl, 2-carboxamidoethyl, tert-butoxycarbonylmethyl, 2-(tert-butoxycarbonyl)ethyl, 4-(tert-butoxycarbamido)butyl, 4-tert-butoxybenzyl, indolyl-3-methyl, S-(triphenylmethyl)thiomethyl, 1-(triphenylmethyl)imidazolyl-4-methyl, 3-(N G -mesitylenesulfonyl)guanidinopropyl, N-xanthylcarboxamidomethyl, 2-(N-xanthylcarboxamido)ethyl or S-(acetamidomethyl)thiomethyl; or R 1 and R 2 together represent propylene radical. Methods for the preparation of said derivatives are provided, and a process for solid phase peptide synthesis using said derivatives is described.

专利号:CN-1241935-C
优先权日:2003-06-10
标 题 :A kind of Thymopentin liquid-phase synthesis method