CAS: 2732-80-1; 2-Bromo-1-Chloro-4-Methoxybenzene

上下游产品

CAS号2401-24-3 2-氯-5-甲氧基苯胺 | CAS号10298-80-3 3-硝基-4-氯苯甲醚 | CAS号50586-69-1 2,3,6-tribromo-... | CAS号13659-24-0 3-溴-4-氯苯酚 | CAS号77-78-1 硫酸二甲酯 | CAS号6280-89-3 2-氯-5-甲氧基苯甲 酸 | CAS号13659-24-0 3-溴-4-氯苯酚 | CAS号1771-19-3 3-methoxy-10H-p...

4-氯-3-硝基苯甲醚置于频哪醇,Bis(N,N-Dimethylformamide)Dichlorodioxomolybdenum(Vi),2-甲基-2-硝基丙烷,氢溴酸,Copper(I) Bromide体系中,用 水,乙腈 用作溶剂,化学反应 1.5H,反应生成3-溴-4-氯苯甲醚
参考文献:通过连续一锅钼催化还原/sandmeyer 反应从硝基芳烃直接合成卤代芳烃
标题:通过连续一锅钼催化还原/sandmeyer 反应从硝基芳烃直接合成卤代芳烃
摘要:在此,我们报道了在连续的一锅操作中从硝基芳烃直接合成各种官能化芳香族溴化物,氯化物,碘化物和氟化物.该方案基于耐空气和耐湿气的二氧钼催化硝基芳香族化合物的还原,采用频哪醇作为还原剂,从而实现后续的重氮化和卤化步骤.该方法代表了直接从硝基芳族化合物合成卤代芳族化合物的经济,实用和替代程序.
Doi:10.1039/d3Ob01187A

专利信息

专利号:WO-2025119975-A1
优先权日:2023-12-04
标 题:A method for synthesis of harmine
发明人：HETT ROBERT; GRAB HANUSCH; LAGOUTTE ROMAN
权利人:RECONNECT LABS AG
摘要:The invention relates to a method of synthesis of a compound of formula (I), harmine, according to the method comprising a step of transforming the compound of formula (II), into the compound of formula (I). The invention further relates to a compound of formula (II), which is an intermediate in synthesis of harmine according to the present invention.

专利号:US-7884125-B2
优先权日:2008-04-30
标 题:Straightforward entry to 7-azabicyclo[2.2.1]heptane-1-carbonitriles and subsequent synthesis of epibatidine analogues
发明人：STEVENS CHRISTIAN; HEUGEBAERT THOMAS
权利人:UNIV GENT
摘要:The present invention relates to a group of substituted-7-azabicyclo-[2.2.1]heptyl derivatives with biological activity. The present invention also relates to synthetic methods for producing said substituted-7-azabicyclo-[2.2.1]heptyl derivatives. The present invention also relates to certain intermediates for producing such substituted-7-azabicyclo-[2.2.1]heptyl derivatives, as well as a synthetic method for producing such intermediates. The present invention also relates to pharmaceutical compositions comprising such substituted-7-azabicyclo-[2.2.1]heptyl derivatives, as well as their use as medicaments for the treatment of diseases mediated by a Nicotinic Acetylcholine Receptor or a receptor being a member of the Neurotransmitter-gated Ion Channel Superfamily, such as pain, Alzheimer's disease, Parkinson's disease, schizophrenia, epilepsy and nicotine addiction.

专利号:US-2009275616-A1
优先权日:2008-04-30
标 题 :Straightforward entry to 7-azabicyclo[2.2.1]heptane-1-carbonitriles and subsequent synthesis of epibatidine analogues