CAS: 151169-67-4; 4-Chloro-3-Nitrophenylboronic Acid

该化合物是一种碳酸衍生物,经常用作铃木-宫浦交叉反应的关键中间体,能够合成制药和材料化学中的双aryl化合物,其硝化和氯替代成分可增强活性和选择性,使其对建设复杂的芳香系统具有价值;该化合物在标准处理条件下具有良好稳定性,并与一系列催化剂和溶剂相兼容;其高纯度和一贯性能使其适合研究和工业应用,特别是在农用化学,制药和先进有机材料的开发方面;建议在惰性条件下适当储存以保持稳定.

英文名称4-Chloro-3-Nitrophenylboronic Acid
中文名称4-氯-3-硝基苯硼酸
IUPAC名称(4-chloro-3-nitrophenyl)boronic acid
其它别名4-氯-3-硝基苯基硼酸; Boronic Acid,(4-Chloro-3-Nitrophenyl)-; 4-Chloro-3-Nitrobenzeneboronicacid
CAS编号151169-67-4
MFCD编号:MFCD02258950
EINECS号:639-352-0
分子式:C6H5BClNO4
分子量:201.37
产品CID: 736606
产品分类有机原料→分子砌块→芳环类化合物→苯类化合物

相似结构搜索
InChIKey: LQCCRPUZTXKDGB-UHFFFAOYSA-N
InChI=1S/C6H5BClNO4/c8-5-2-1-4(7(10)11)3-6(5)9(12)13/h1-3,10-11H…
计算化学: 氢键受体数4.0氢键供体数2.0可旋转键数2.0

相似化合物

913836-26-7 867333-29-7 1218908-71-4

MSDS等安全信息

GHS象形图
GHS符号GHS07;
注释: Exclamation mark
危险类别特定目标器官毒性 - 单次接触类别3
皮肤腐蚀/刺激类别2
严重眼刺激类别2
急性毒性类别4(经口)
严重眼刺激类别2A
警示词Warning(警告)
危险描述H335 |可能引起呼吸道刺激.
H315 |造成皮肤刺激.
H319 |造成严重眼刺激.
H302 |吞咽有害.
防范说明P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
危险等级IRRITANT
危险品标志Xi
安全声明26-36/37/39-36
危险类别码36/37/38

欧盟法规

C&L通报

合成工艺路线路线简述

海关参考信息

2903919090-氯苯
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专利信息

专利号:US-9744252-B2
优先权日:2011-08-17
标题:Compounds for binding to the platelet specific glycoprotein IIb/IIIa and their use for imaging of thrombi
发明人：BERGER MARKUS; KRUGER MARTIN; LOHRKE JESSICA; REINHARDT MICHAEL; SIEBENEICHER HOLGER
权利人:PIRAMAL IMAGING SA
摘要:The present invention relates to novel fluorine containing compounds, methods for their preparation, the intermediates of the synthesis, their use as diagnostic agents, especially for imaging of thrombi. The invention relates to positron emission tomography (PET) agents and associated precursor reagents, and methods for producing such radiolaveled agents for imaging of thrombi in a mammalian body. More particularly, the invention relates to small nonpeptide, high-affinity, specific-binding glycoprotein IIb/IIIa antagonists for imaging of thrombi.