CAS: 3938-96-3; Ethyl Methoxyacetate

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623-50-7 625-45-6 817-95-8

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CAS号64-17-5 乙醇 | CAS号625-45-6 甲氧基乙酸 | CAS号623-73-4 重氮乙酸乙酯 | CAS号67-56-1 甲醇 | CAS号38870-89-2 甲氧基乙酰氯 | CAS号6044-68-4 丙烯醛二甲缩醛 | CAS号6773-29-1 重氮丙二酸二甲酯 | CAS号1738-36-9 甲氧基乙腈 | CAS号149-73-5 原甲酸三甲酯 | CAS号124-41-4 甲醇钠 | CAS号3587-64-2 1-甲氧基-2-甲基-2-丙醇 | CAS号37088-66-7 (S)-3-氨基-3-苯基丙酸甲酯 | CAS号37088-67-8 (R)-3-氨基-3-苯基 丙酸甲酯 | CAS号100-41-4 乙苯 | CAS号36283-44-0 (R)-N-(1-苯乙基)乙酰胺 | CAS号1903-90-8 6-Hydroxy-2-(me... | CAS号2627-86-3 (S)-(-)-α-甲基苄胺 | CAS号3886-69-9 R(+)-alpha-甲基苄胺 | CAS号162929-44-4 2-methoxy-N-[(1...

乙醇,甲氧基乙腈置于盐酸体系中,化学反应生成甲氧基乙酸乙酯
参考文献:Gauthier,Annales De Chimie (Cachan,France),1909,Vol. <8>16,P. 318
标题:Gauthier,Annales De Chimie (Cachan,France),1909,Vol. <8>16,P. 318

专利信息

专利号:US-10308588-B2
优先权日:2014-12-15
标 题 :Synthesis of amides and amines from aldehydes or ketones by heterogeneous metal catalysis
发明人：CÓRDOVA ARMANDO; PALO-NIETO CARLOS; AFEWERKI SAMSON
权利人:ORGANOFUEL SWEDEN AB
摘要:A mild and efficient synthesis of primary amines and amides from aldehydes or ketones using a heterogeneous metal catalyst and amine donor is disclosed. The initial heterogeneous metal-catalyzed reaction between the carbonyl and the amine donor components is followed by the addition of a suitable acylating agent component in one-pot, thus providing a catalytic one-pot three-component synthesis of amides. Integration of enzyme catalysis allows for eco-friendly one-pot co-catalytic synthesis of amides from aldehyde and ketone substrates, respectively. The process can be applied to asymmetric synthesis or to the co-catalytic one-pot three-component synthesis of capsaicin and its analogues from vanillin or vanillyl alcohol. A co-catalytic reductive amination/dynamic kinetic resolution (dkr) relay sequence for the asymmetric synthesis of optically active amides from ketones is disclosed. Implementation of a catalytic reductive amination/kinetic resolution (kr) relay sequence produces the corresponding optically active amide product and optical active primary amine product with the opposite stereochemistry from the starting ketones.

专利号:US-2024229089-A1
优先权日:2021-04-30
标 题 :A process for enzymatic synthesis of amides from amines and carboxylic acids or esters
发明人：LIN SHUANGZHENG; CORDOVA ARMANDO; DEIANA LUCA; IBRAHEM ISMAIL
权利人:XP CHEMISTRIES AB
摘要:The present invention relates to A process for enzymatic synthesis of amides of formula (III) from amines of formula (I) and compounds of formula (II). characterized in that the lipase is immobilized on a rotary bed reactor or on a spin-fixed-bed reactor and a Dean-Stark apparatus is used for dehydration.

专利号:US-10975096-B2
优先权日:2014-06-20
标题 :Synthesis of polycyclic-carbamoylpyridone compounds
发明人：CHIU ANNA; ENQUIST JR JOHN; GRIGGS NOLAN; HALE CHRISTOPHER; IKEMOTO NORIHIRO; KEATON KATIE ANN; KRAFT MATT; LAZERWITH SCOTT E; LEEMAN MICHEL; PENG ZHIHUI; SCHRIER KATE; TRINIDAD JONATHAN; VAN HERPT JOCHEM; WALTMAN ANDREW W
权利人:GILEAD SCIENCES INC
摘要:Methods of making compounds of Formula I are disclosed:

专利号:WO-2023286078-A1
优先权日:2021-07-13
标题:An improved process for the preparation of an intermediate of baloxavir morboxil
发明人：TALASANI SHYAM SUNDER REDDY; BUDIDETI SHANKAR REDDY; KOTTE RAJASHEKAR; SATTI VENKATA REDDY; MALA NAGENDRA; MUDDASANI PULLA REDDY; NANNAPANENI VENKAIAH CHOWDARY
权利人:NATCO PHARMA LTD
摘要:The present invention provides an improved process for the preparation of (12aR)-3,4,12,12a-tetrahydro-7-(phenylmethoxy)-1H-[1,4]oxazino[3,4-c] pyrido[2,1-f] [1,2,4]triazine-6,8-dione of Formula (I). Formula I which is a key intermediate in the synthesis of Baloxavir Morboxil of Formula (II).

专利号:US-2024400552-A1
优先权日:2016-11-11
标题 :Heterocyclic modulators of lipid synthesis
发明人：BUCKLEY DOUGLAS I; DUKE GREGORY; WAGMAN ALLAN S; EVANCHIK MARC; MCDOWELL ROBERT S
权利人:SAGIMET BIOSCIENCES INC
摘要:Compounds that are fatty acid synthesis modulators are provided. The compounds may be used to treat disorders characterized by dysregulation of the fatty acid synthase function by modulating the function and/or the fatty acid synthase pathway. Methods are provided for treating such disorders including viral infections, such as hepatitis C infection, cancer and metabolic disorders, such as non-alcoholic steatohepatitis (NASH).

专利号:US-11622968-B2
优先权日:2011-03-08
标 题:Heterocyclic modulators of lipid synthesis
发明人：BUCKLEY DOUGLAS; DUKE GREGORY; WAGMAN ALLAN S; EVANCHIK MARC; MCDOWELL ROBERT S
权利人:SAGIMET BIOSCIENCES INC
摘要:Compounds that are fatty acid synthesis modulators are provided. The compounds may be used to treat disorders characterized by disregulation of the fatty acid synthase function by modulating the function and/or the fatty acid synthase pathway. Methods are provided for treating such disorders including viral infections, such as hepatitis C infection, cancer and metabolic disorders, such as non-alcoholic steatohepatitis (NASH).