CAS: 49617-83-6; 1-(Bromomethyl)-3-Iodobenzene

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CAS号625-95-6 3-甲碘苯 | CAS号112089-12-0 9-[(3-iodopheny... | CAS号141763-48-6 3-(3-Iodophenyl... | CAS号1878-69-9 3-碘苯乙酸 | CAS号696-41-3 3-碘苯甲醛 | CAS号696-40-2 3-碘苄胺 | CAS号130723-54-5 3-碘苯乙腈 | CAS号21906-35-4 1-(3-iodophenyl... | CAS号20854-56-2 (4-甲氧基联苯-3-基)-甲醇 | CAS号757181-13-8 (4-fluorophenyl... | CAS号832744-17-9 1-(benzenesulfo...

3-碘苯甲酸置于硼烷四氢呋喃络合物,三溴化磷体系中,用 四氢呋喃,二氯甲烷 作为反应溶剂,化学反应生成 3-碘苄溴
参考文献:由手性阳离子引导的对映选择性分子间 C-H 胺化
标题:由手性阳离子引导的对映选择性分子间 C-H 胺化
摘要:C(Sp 3)-H 键的对映选择性胺化是一种强大的合成转化,但在分子间意义上实现却极具挑战性.我们开发了一系列用于 Rh 催化的 C-h 胺化的一流催化剂的阴离子变体,Rh 2 (Esp) 2,我们将衍生自季铵化金鸡纳生物碱的手性阳离子与它们相关联.这些离子对催化剂能够在带有侧羟基的底物的苄基 C-H 胺化中实现高水平的对映选择性.此外,手性阳离子的喹啉似乎与铑络合物进行轴向连接,与 Rh 2 (Esp) 2相比,提供了更高的产物产率并突出阳离子所发挥的双重作用.这些结果强调了使用手性阳离子在具有挑战性的过渡金属催化转化中控制对映选择性的潜力.
DOI:10.1021/jacs.1C05206

专利信息

专利号:US-8101665-B2
优先权日:2007-12-17
标题 :Process for synthesis of tritiated and deuterated thiorphan and acetorphan
发明人：MASJEDIZADEH MOHAMMAND R; WU SHAO-YONG
权利人:MASJEDIZADEH MOHAMMAND R; WU SHAO-YONG; ROCHE PALO ALTO LLC
摘要:Methods for preparing tritium or deuterium labeled thiorphan comprising reacting a compound of formula j n nwherein m is from 1 to 5 and X is halo, with Z 2 wherein Z is tritium or deuterium, in the presence of a catalyst, to form a compound of formula kn n nwherein n is from 1 to 5, provided that n is less than or equal to m.

专利号:US-10053423-B2
优先权日:2014-01-03
标 题:Radioiodinated compounds
发明人：DIMAGNO STEPHEN; HU BAO
权利人:NUTECH VENTURES
摘要:This disclosure relates to reagents and methods useful in the synthesis of aryl iodines, for example, in the preparation of iodine labeled radiotracers. The reagents and methods provided herein may be used to access a broad range of compounds, including aromatic compounds, heteroaromatic compounds, amino acids, nucleotides, and synthetic compounds.

专利号:WO-2009077386-A1
优先权日:2007-12-17
标 题:Process for synthesis of tritiated and deuterated thiorphan and acetorphan

专利号:US-2011319656-A1
优先权日:2007-12-17
标题:Process for synthesis of tritiated and deuterated thiorphan and acetorphan

专利号:US-9738661-B2
优先权日:2006-10-27
标题:HCV NS3 protease inhibitors
发明人：LIVERTON NIGEL J; SUMMA VINCENZO; HARPER STEVEN; MCCAULEY JOHN A; ROMANO JOSEPH J; RUDD MICHAEL T
权利人:MERCK SHARP & DOHME; MSD ITALIA SRL
摘要:The present invention relates to macrocyclic compounds of formula (I) that are useful as inhibitors of the hepatitis C virus (HCV) NS3 protease, their synthesis, and their use for treating or preventing HCV infections.

专利号:CN-107118212-A
优先权日:2017-05-26
标 题:A kind of β-carboline compound and its synthesis method and application