CAS: 1484-84-0; 2-Piperidineethanol

相似化合物

103639-57-2 787622-24-6 786684-21-7

上下游产品

CAS号103-74-2 2-吡啶乙醇 | CAS号7440-18-8 钌 | CAS号134256-32-9 N-benzyl-2-(2-h... | CAS号110-89-4 六氢吡啶 | CAS号103639-57-2 (S)-2-(哌啶-2-基)乙醇 | CAS号68419-38-5 (r)-1-(+)-2-哌啶乙醇 | CAS号60012-49-9 2-(2-氯乙基)哌啶盐酸盐 | CAS号533-15-3 N-甲基-哌啶乙醇 | CAS号19832-04-3 2-哌啶乙酸 | CAS号118811-03-3 N-叔丁氧羰基-2-哌啶-2-基乙醇 | CAS号340962-94-9 1-B°C-4-[2-(2-h... | CAS号153108-62-4 tert-butyl-dime... | CAS号183859-36-1 N-B°C-2-哌啶乙酸甲酯 | CAS号250249-85-5 (R)-1-N-B°C-哌啶-2-乙醇

(2S,3Ar)-8-Benzyl-2-(2-Methylpropoxy)-3,3A,4,5,6,7-Hexahydro-2H-[1,2]Oxazolo[2,3-A]Pyridin-8-Ium;Bromide置于palladium On Activated Charcoal,Lithium Aluminium Tetrahydride,Ammonium Formate体系中,用 四氢呋喃,甲醇 用作溶剂,化学反应 15.0H,反应生成2-哌啶乙醇
参考文献:Carruthers,William; Moses,Roger C.,Journal Of The Chemical Society. Perkin Transactions I,1988,P. 2251-2254
标题:Carruthers,William; Moses,Roger C.,Journal Of The Chemical Society. Perkin Transactions I,1988,P. 2251-2254

专利信息

专利号:US-8076479-B2
优先权日:2006-08-28
标题 :Process and intermediates for the synthesis of (3-alkyl-5-piperidin-1-yl-3,3a-dihydro-pyrazolo[1,5-a]pyrimidin-7-yl)-amino derivatives and intermediates
发明人：CHEN FRANK XING; KEERTIKAR KARTIK M; KUO SHEN-CHUN; LEE HONG-CHANG; RAGHAVAN RAMANI R; WU GEORGE G; XIE JI
权利人:CHEN FRANK XING; KEERTIKAR KARTIK M; KUO SHEN-CHUN; LEE HONG-CHANG; RAGHAVAN RAMANI R; WU GEORGE G; XIE JI; SCHERING CORP
摘要:Disclosed is a process for the synthesis of compounds of Formula I n nby sequentially aminating, first with a primary amine and then with a secondary amine, an intermediate compound of the structure of Formula E1,n n nwherein R 1 is a linear, branched, or cyclic alkyloxy functional group of the structure (—R 2a —OH), R 2a is a linear, branched or cyclic alkyl group, R 2 is a linear, branched or cyclic alkyl group, and R 3 is an alkylene-heterocycle, said process comprising forming intermediate compound of Formula E1 by reacting, in a refluxing reaction solvent selected from alcohols having 5 or less carbon atoms and mixtures of two or more thereof, a methanol solution of a salt of a 4-alkyl-3-amino-pyrazole compound of Formula C1,n n nwith a diamidization reagent selected from dimethylmalonate, monomethylmalonyl-chloride, and malonyl dichloride in the presence of a Lewis base having sufficient proton affinity to abstract a proton from the 1-position nitrogen on the pyrazole ring.

专利号:EP-2051963-B1
优先权日:2006-08-18
标题:Process for resolving chiral piperidine alcohol and process for synthesis of pyrazolo [1,5-a]pyrimidine derivatives using same
发明人：CHEN FRANK XING; TAMAREZ MARIA M; XIE JI
权利人:SCHERING CORP
摘要:The present invention provides a method of resolving piperdin-yl- alkylene-alcohols, in high yield at high enantiomeric purity, for example 2- piperidin-2-yl-ethanol.

专利号:US-7786306-B2
优先权日:2006-08-18
标 题 :Process for resolving chiral piperidine alcohol and process for synthesis of pyrazolo[1,5-a] pyrimidine derivatives using same
发明人：CHEN FRANK XING; TAMAREZ MARIA M; XIE JI
权利人:SCHERING CORP
摘要:The present invention provides a method of resolving piperdin-yl-alkylene-alcohols, in high yield at high enantiomeric purity, for example 2-piperidin-2-yl-ethanol.

专利号:US-9562037-B2
优先权日:2014-02-26
标题:Synthesis and use of amine-containing flavonoids as potent anti-leishmanial agents
发明人：CHOW LARRY MING-CHEUNG; CHAN WILLIAM TAK HANG; CHAN KIN-FAI; WONG IRIS LAI KING; KAN WING-YIU
权利人:UNIV HONG KONG POLYTECHNIC
摘要:The present invention relates to novel series of amine-containing flavonoids and compositions containing the compounds, as well as the synthesis and the use of the same. The invention also relates to methods of treatment and prevention of diseases, in particular, parasitic infections including Leishmaniasis, comprising administration of the compounds.

专利号:US-2004053999-A1
优先权日:1997-09-17
标题 :Novel compounds and methods for synthesis and therapy
发明人：BISCHOFBERGER NORBERT W; DAHL TERRENCE C; HITCHCOCK MICHAEL J M; KIM CHOUNG U; LEW WILLARD; LIU HONGTAO; MILLS ROGER G; WILLIAMS MATTHEW A
摘要:Novel compounds are described. The compounds generally comprise an acidic group, a basic group, a substituted amino or N-acyl and a group having an optionally hydroxylated alkane moiety. Pharmaceutical compositions comprising the inhibitors of the invention are also described. Methods of inhibiting neuraminidase in samples suspected of containing neuraminidase are also described. Antigenic materials, polymers, antibodies, conjugates of the compounds of the invention with labels, and assay methods for detecting neuraminidase activity are also described.

专利号:US-6225341-B1
优先权日:1995-02-27
标 题:Compounds and methods for synthesis and therapy
发明人：BISCHOFBERGER NORBERT W; KIM CHOUNG U; LEW WILLARD; LIU HONGTAO; WILLIAMS MATTHEW A
权利人:GILEAD SCIENCES INC
摘要:Novel compounds are described. The compounds generally comprise an acidic group, a basic group, a substituted amino or N-acyl and a group having an optionally hydroxylated alkane moiety. Pharmaceutical compositions comprising the inhibitors of the invention are also described. Methods of inhibiting neuraminidase in samples suspected of containing neuraminidase are also described. Antigenic materials, polymers, antibodies, conjugates of the compounds of the invention with labels, and assay methods for detecting neuraminidase activity are also described.