CAS: 312-30-1; 4,4'-Sulfonylbis(1-Fluoro-2-Nitrobenzene)

该化合物是一个有机化合物,其特征是其磺酰功能组,将两个4-氟-3-硝基苯酸酯联系起来;该化合物一般在室温时是固体,以其在有机合成中的潜在应用和作为各种化学实体生产过程中的中间体而著称;硝基化合物的存在助长了其电子提取特性,从而影响其反应和化学反应中的回动和相互作用;氟基替代成分增强了化合物的稳定性,并可能影响其溶性性和极性;此外,该混合物组是一个多功能组,可以参与各种化学转化,使这一组合在学术研究和工业应用中都具有兴趣;在处理该物质时,应当采取安全防范措施,因为它可能对健康造成危害,包括毒性和环境危害.

结构式图片

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

CAS号383-29-9 4,4'-二氟二苯砜 | CAS号462-06-6 氟苯 | CAS号349-88-2 4-氟苯磺酰氯 | CAS号40939-65-9 3,3'-二氨基-4,4'-二氟二苯砜

合成工艺路线路线简述

  • 合成目标产物 Bis(4-Fluoro-3-Nitrophenyl) Sulfone 主要起始原料 4-Fluorobenzenesulfonyl Chloride
  • (文献来源)合成步骤主要原料 4-Fluorobenzenesulfonyl Chloride
4,4'-二氟二苯砜置于硫酸,硝酸体系中,化学反应生成 4,4ˊ-二氟-3,3ˊ-二硝基二苯砜
参考文献:Zahn; Zuber,Chemische Berichte,1953,Vol. 86,P. 172,180
标题:Zahn; Zuber,Chemische Berichte,1953,Vol. 86,P. 172,180

海关参考信息

专利信息


专利号:US-4795828-A
优先权日:1983-01-03
标题 :Functionalized intermediate for the synthesis of alpha-functionalized derivatives and labeled conjugates of procaimamide and NAPA
发明人:BUCKLER ROBERT T; WARD FREDERICK E
权利人:MILES INC
摘要:Procainamide and N-acetylprocainamide (NAPA) immunogens, antibodies prepared therefrom, labeled conjugates, synthetic intermediates, and the use of such antibodies and labeled conjugates in immunoassays for determining the respective drugs. The immunogens comprise the drugs coupled at the alpha -position of the amide side chain to an immunogenic carrier material. The labeled conjugates and synthetic intermediates similarly are alpha -position derivatives of the drugs or precursors thereof. The antibodies and labeled conjugates are particularly useful in homogeneous nonradioisotopic immunoassays for measuring the respective drugs in biological fluids such as serum.

专利号:WO-2009056955-A1
优先权日:2007-10-30
标题 :Amine-bearing phospholipids (abps), their synthesis and use
发明人:ZUMBUEHL ANDREAS
权利人:UNIV BASEL; ZUMBUEHL ANDREAS
摘要:Disclosed herein are amine-bearing phospholipids (ABP). The ABPs display many properties and functionalities of naturally occurring phospholipids, but also new properties and functionalities, such as the ability to polymerize while maintaining structural integrity, that may supplement or expand the functionalities of naturally occurring phospholipids.

专利号:US-9988657-B2
优先权日:2014-02-27
标 题 :Enzymatic hydrolysis of disaccharides and oligosaccharides using alpha-glucosidase enzymes
发明人:NAGY KEVIN D; HAGO ERWIN COLUMBUS; SHETTY JAYARAMA K; HENNESSEY SUSAN MARIE; DICOSIMO ROBERT; HUA LING; RAMIREZ RODRIGO; TANG ZHONGMEI; YU ZHEYONG
权利人:DU PONT
摘要:A method is disclosed for hydrolyzing an alpha-1,3 or alpha-1,6 glucosyl-glucose linkage in a saccharide (disaccharide or oligosaccharide). This method comprises contacting the saccharide with an alpha-glucosidase enzyme such as transglucosidase under suitable conditions, during which contacting step the enzyme hydrolyzes at least one alpha-1,3 or alpha-1,6 glucosyl-glucose linkage of the saccharide. This method is useful for reducing the amount of oligosaccharides in a filtrate isolated from a glucan synthesis reaction, for example.

专利号:CN-110582293-A
优先权日:2017-03-31
标题 :Synthesis factor compositions and methods of use
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合成参考文献


参考文献:10.1128/aac.41.2.385
摘要:Neamati N, Mazumder A, Zhao H, Sunder S, Burke TR, Schultz RJ, Pommier Y. Diarylsulfones, a novel class of human immunodeficiency virus type 1 integrase inhibitors. Antimicrob Agents Chemother. 1997 Feb;41(2):385–93.
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