- 英文名称5,6,7,8-Tetrahydroquinoxaline
- 中文名称5,6,7,8-四氢喹喔啉
- IUPAC名称5,6,7,8-tetrahydroquinoxaline
- 其它别名环己烷并吡嗪; 5678四氢喹喔啉; Quinoxaline, 5,6,7,8-Tetrahydro-; 5,6,7,8-Tetrahydroquinoxaline
- CAS编号34413-35-9
- MFCD编号:MFCD00038078
- EINECS号:252-002-8
- FDA UNII编号:M153CJ9RA0
- 分子式:C8H10N2
- 分子量:134.18
- 产品CID: 1346866
- 产品分类有机原料→分子砌块→芳杂环类化合物→吡嗪类化合物
相似化合物
155535-20-9 34413-35-9 1784074-98-1欧盟法规
ECHA物质C&L通报REACH预注册上下游产品
2,3-diethynylquinoxaline pyrazine2-Benzoyl-5,6,7,8-tetrahydr°Cyclohexapyrazine pyrazine2-Cyclohexanoyl-5,6,7,8-tetrahydr°Cyclohexapyrazine (R,S)-5-bromo-5,6,7,8-tetrahydroquinoxaline 5,6,7,8-tetrahydroquinoxaline N-oxide diazomethane 5,6,7-trihydroxy-2-phenyl-4H-1-benzopyran-4-one dimethyl sulfate methyl iodide 5,6,7-trihydroxy-2-phenyl-4H-1-benzopyran-4-one 5,6,7-Trimethoxy-3-methylflavone mosloflavone 3-hydroxy-5,6,7-trimethoxy-2-phenyl-4H-benzopyran-4-one 合成工艺路线路线简述
- 合成目标产物 5,6,7,8-Tetrahydroquinoxaline 主要起始原料 Quinoxaline
- (文献来源)合成步骤主要原料 Quinoxaline
(5As,9Ar)-3-Phenyl-5A,6,7,8,9,9A-Hexahydro-1H-1,5-Benzodiazepine 以50%的收率获得产物5,6,7,8-四氢喹喔啉
参考文献:气相热解2,3-二氢-1,4-二氮杂卓类化合物:环的饱和部分参与化学反应和稠合环系统的新型顺式-反式异构化
标题:气相热解2,3-二氢-1,4-二氮杂卓类化合物:环的饱和部分参与化学反应和稠合环系统的新型顺式-反式异构化
摘要:2,450-550oc范围内的2,3-二氢-1,4-二氮杂卓的快速真空热解涉及分子的饱和部分与vinamidine系统的相互作用,并导致氘建立的1,5-氢转移标记实验;在较高温度下,发生环收缩,从而得到吡嗪作为主要产物.
DOI:10.1039/c39950002337
专利信息
专利号:US-7138526-B1
优先权日:1999-06-15
标 题 :Solid phase synthesis of n,n-disubstituted diazacycloalkylcarboxy derivatives
发明人:HERPIN TIMOTHY F; MORTON GEORGE C; SALVINO JOSEPH M
权利人:AVENTIS PHARMA INC
摘要:A method for the solid phase synthesis of N,N-disubstituted diazacycloalkylcarboxy derivatives of general formula (I) and (II) is claimed. Examples include piperazine-2-carboxamide. The method is applicable to the synthesis or large combinatorial libraries
专利号:US-6127515-A
优先权日:1997-11-18
标 题:Functionalized resin for the synthesis of amides and peptides
发明人:MANFRE FRANCO; VANASSE BENOIT J; LABAUDINIERE RICHARD F; MORTON GEORGE C
权利人:AVENTIS PHARM PROD INC
摘要:This invention is directed to a functionalized amino resin of formula ##STR1## wherein S is a solid support; R is H or alkyl; A is ##STR2## Y is OH or OCOR 1 ; and R 1 is aliphatic or aromatic which is useful for the solid phase synthesis of amides, peptides and hydroxamic acids.
专利号:US-6133409-A
优先权日:1996-12-19
标 题:Process for the solid phase synthesis of aldehyde, ketone, oxime, amine, hydroxamic acid and αβ-unsaturated carboxylic acid and aldehyde compounds
发明人:SALVINO JOSEPH M; MORTON GEORGE C; MASON HELEN J; LABAUDINIERE RICHARD F
权利人:AVENTIS PHARM PROD INC
摘要:This invention is directed to a process for the solid phase synthesis of aldehyde, ketone, oxime, amine, hydroxamic acid and alpha , beta -unsaturated carboxylic acid and aldehyde compounds and to polymeric hydroxylamine resin compounds useful therefor.
专利号:US-6710208-B2
优先权日:1996-12-19
标题 :Process for the solid phase synthesis of aldehyde, ketone, oxime, amine, hydroxamic acid and α,β-unsaturated carboxylic acid and aldehyde compounds
发明人:SALVINO JOSEPH M; MORTON GEORGE C; MASON HELEN J; LABAUDINIERE RICHARD F
权利人:AVENTIS PHARMA INC
摘要:This invention is directed to a process for the solid phase synthesis of aldehyde, ketone, oxime, amine, hydroxamic acid and α,β-unsaturated carboxylic acid and aldehyde compounds and to polymeric hydroxylamine resin compounds useful therefor.
专利号:US-7129357-B2
优先权日:2003-09-15
标题:Synthesis of quinoline 5-carboxamides useful for the preparation of PDE IV inhibitors
发明人:ANDREWS DAVID R; TANG SUHAN; WU WENXUE; KALLINEY SAMI Y; SUDHAKAR ANANTHA; NIELSEN CHRISTOPHER
权利人:SCHERING CORP
摘要:In one embodiment, the present application discloses a process for making the compound of the formula:
专利号:WO-2009042013-A1
优先权日:2007-08-02
标题:Process for the synthesis of e1 activating enzyme inhibitors