CAS: 4193-55-9; Sodium 6,6'-(Ethene-1,2-Diyl)Bis(3-((4-(Bis(2-Hydroxyethyl)Amino)-6-(Phenylamino)-1,3,5-Triazin-2-yl)Amino)Benzenesulfonate)

专利信息

专利号:WO-8909270-A1
优先权日:1988-03-22
标 题:Method for altering surface charge of microorganisms
发明人：EASSON DONALD D JR; SINSKEY ANTHONY J; PEOPLES OLIVER P
权利人:MASSACHUSETTS INST TECHNOLOGY
摘要:The present invention is a method to produce polysaccharides with altered functional groups on their surface having modified surface charge as a result of the altered functional groups. These functional groups include, but are not limited to, negatively charged pyruvyl and succinyl moieties and positively charged amino groups. The polysaccharides can be produced by either: (1) mutation and selection of organisms synthesizing polysaccharides with modified surface charge or (2) engineering of specific genes within organisms to alter the charged groups attached to the polysaccharides during synthesis. Mutation of Zoogloea ramigera polysaccharide, as measured by the change in pyruvate content, is demonstrated. The isolation, characterization and manipulation of the gene for the pyruvyl transferase enzyme, which adds pyruvyl moities to the exopolysaccharide produced by Zoogloea ramigera, leading to an exopolysaccharide having a modified surface charge, is detailed. The modified exopolysaccharides have new applications due to the differences in surface charge. The modified enzymes and sequences regulating their expression can be used to produce novel polysaccharides. Further, studies of the structural-functional relationships of the modified exopolysaccharide can lead to a better understanding of secondary and tertiary structure in polysaccharides.

专利号:WO-8800948-A1
优先权日:1986-07-28
标 题:Method to control and produce novel biopolymers
发明人：SINSKEY ANTHONY J; EASSON DONALD DAVIDSON JR; RHA CHOKYUN
权利人:MASSACHUSETTS INST TECHNOLOGY
摘要:A method for identifying, characterizing, utilizing and modifying a set of genes which interact to produce a specific polymer. The method is demonstrated for production of an exocellular polysaccharide produced by the bacteria Zoogloea ramigera. The isolated polysaccharide is useful as a viscosity modifier, oil field chemical, drag reducing agent, dispersant or flocculant. Modification of the isolated genes, for example, by insertion of a regulatable promoter, provides a means for alteration of the enzymes responsible for synthesis of the polysaccharide and its resulting structure.

专利号:CN-101544988-B
优先权日:2009-05-13
标 题:The Gene BC1L4 Controlling Rice Cellulose Synthesis as Application of Rice Genetic Improvement

专利号:CN-101544988-A
优先权日:2009-05-13
标题 :The Gene BC1L4 Controlling Rice Cellulose Synthesis as Application of Rice Genetic Improvement