CAS: 6325-93-5; 4-Nitrobenzenesulfonamide

上下游产品

CAS号98-74-8 4-硝基苯磺酰氯 | CAS号349-96-2 对硝基苯磺酰氟 | CAS号49690-09-7 N-叔丁基-4-硝基苯磺酰胺 | CAS号23530-48-5 N-异丙基-4-硝基苯磺酰胺 | CAS号89840-82-4 N,N-二乙基4-硝基苯磺酰胺 | CAS号100-41-4 乙苯 | CAS号25309-64-2 1-乙基-4-碘苯 | CAS号292638-84-7 phenylene-ethylene | CAS号135-98-8 仲丁基苯 | CAS号109845-76-3 N-(4-methylphen... | CAS号496-14-0 二氢异苯并呋喃 | CAS号1393686-94-6 2-(4-nitropheny... | CAS号349-96-2 对硝基苯磺酰氟 | CAS号493-05-0 异色满 | CAS号64880-92-8 2-((4-nitrophen... | CAS号194156-25-7 (2R)-1-(4-nitro... | CAS号194156-28-0 (2S)-1-(4-nitro... | CAS号193904-48-2 2-benzyl-1-(4-n... | CAS号28860-08-4 Benzenesulfonam...

P-Nitrobenzenesulfonyl Azide置于四氢呋喃体系中,用 四氢呋喃 作为反应溶剂,化学反应 1.0H,以95%的收率获得产物4-硝基苯磺酰胺
参考文献:一锅中醚的光化学ch胺化和geminal Difunctionalization反应.
标题:一锅中醚的光化学ch胺化和geminal Difunctionalization反应.
摘要:据报道,使用相对稳定的九氟丁烷磺酰基(nonaflyl,Nf)叠氮化物作为胺化试剂进行醚的温和,无原子经济且无金属的α-Ch胺化反应,可得到n-磺酰基半缩醛.这使空前的c(sp3)双官能化反应成为可能,从而导致从一锅中的简单醚开始的各种官能化的含氨基化合物.
DOI:10.1002/anie.201905209

专利信息

专利号:WO-2024186075-A1
优先权日:2023-03-03
标题 :Synthesis method of antibody-drug conjugates using proximity effect-based site-selective antibody labeling
发明人：LEE HYUN SOO; KIM SOOIN; KWEON YONGSEOK
权利人:UNIV SOGANG RES & BUSINESS DEVELOPMENT FOUND; RESEARCH & BUSINESS FOUNDATION SUNGKYUNKWAN UNIV
摘要:The present invention relates to a method for the synthesis of an antibody-drug conjugate using proximity effect-based site-selective antibody labeling. Provided according to the present invention may be a method for the synthesis of an antibody-drug conjugate by site-selectively introducing a drug into an antibody using a pyridinium oxime derivative (labeling mediator protein) introduced into a binding protein containing a non-standard amino acid.

专利号:US-9428524-B2
优先权日:2010-05-25
标 题:Synthetic process for the manufacture of ecteinascidin compounds
发明人：MARTIN LÓPEZ MA JESÚS; FRANCESCH SOLLOSO ANDRÉS; CUEVAS MARCHANTE MARIA DEL CARMEN
权利人:MARTIN LÓPEZ MA JESÚS; FRANCESCH SOLLOSO ANDRÉS; CUEVAS MARCHANTE MARIA DEL CARMEN; PHARMA MAR SA
摘要:This invention relates to compounds of formula II: wherein R 1 , R 2 , Prot SH , and Prot NH are as defined, to processes for the synthesis of ecteinascidins of formula I from compounds of formula II, and to processes for the synthesis of compounds of formula II.

专利号:WO-2025128848-A1
优先权日:2023-12-12
标题:Heterocyclic compounds as triggering receptor expressed on myeloid cells 2 agonists and methods of use
发明人：HOUZE JONATHAN B; PANDYA BHAUMIK
权利人:VIGIL NEUROSCIENCE INC
摘要:The present disclosure provides compounds of Formula (I), useful for the activation of Triggering Receptor Expressed on Myeloid Cells 2 ('TREM2'). This disclosure also provides pharmaceutical compositions comprising the compounds, uses of the compounds, and compositions for treatment of, for example, a neurodegenerative disorder. Further, the disclosure provides intermediates useful in the synthesis of compounds of Formula (I).

专利号:US-8604213-B2
优先权日:2008-10-21
标 题 :Fluorination of aromatic ring systems
发明人：DIMAGNO STEPHEN
权利人:DIMAGNO STEPHEN; NUTECH VENTURES
摘要:This disclosure relates to reagents and methods useful in the synthesis of aryl fluorides, for example, in the preparation of 18 F labeled radiotracers. The reagents and methods provided herein may be used to access a broad range of compounds, including aromatic compounds, heteroaromatic compounds, amino acids, nucleotides, and synthetic compounds.

专利号:US-6583318-B2
优先权日:2001-05-17
标 题:Method for synthesis of α-sulfonamido amide, carboxylic acid and hydroxamic acid derivatives
发明人：CAMPIAN EUGENE; LOU BOLIANG; MJALLI ADNAN M M
权利人:ADVANCED SYNTECH LLC
摘要:A method of synthesizing alpha-sulfonamido amide, carboxylic acid or hydroxamic acid derivatives comprising providing a set of polymer-bound reactant(s) (sulfonamide, aldehyde or ketone, isocyanide or acid) to react with three sets of the other three reactants to form an array of polymer-bound alpha-sulfonamido amide-type intermediates and use of such intermediates for the preparation of combinatorial libraries.

专利号:US-9302990-B2
优先权日:2008-10-21
标 题 :Fluorination of aromatic ring systems
发明人：DIMAGNO STEPHEN GREGORY
权利人:DIMAGNO STEPHEN GREGORY; NUTECH VENTURES
摘要:This disclosure relates to reagents and methods useful in the synthesis of aryl fluorides, for example, in the preparation of 18 F labeled radiotracers. The reagents and methods provided herein may be used to access a broad range of compounds, including aromatic compounds, heteroaromatic compounds, amino acids, nucleotides, and synthetic compounds.