831-23-2 = 91-60-1 反应条件:1.1 Catalysts: Perchloric Acid Solvents: Benzene; 1 H,80 °C 标题:Integration Of A Four-Step Reaction Into One-Pot Under The Coexistence Of Silica-Gel-Supported Acid And Base Reagents: Synthesis Of Benzo- And Naphthothiophenes Using Nahso4/sio2 And Na2Co3/sio2 作者:Hayakawa,Mamiko; Aoyama,Tadashi; Nakaoka,Kyohei; Kosuge,Masayuki; Ouchi,Akihiko 参考文献:Synthesis 日期:2019 卷标:51(12) 页码:2572-2578]
811-51-8 + 580-13-2 = 91-60-1 反应条件:1.1 Reagents: Hydrochloric Acid 标题:Simple Syntheses Of Aryl Alkyl Thioethers And Of Aromatic Thiols From Unactivated Aryl Halides And Efficient Methods For Selective Dealkylation Of Aryl Alkyl Ethers And Thioethers 作者:Testaferri,L.; Tiecco,M.; Tingoli,M.; Chianelli,D.; Montanucci,M. 参考文献:Synthesis 日期:1983 卷标:(9) 页码:751-5]
612-55-5 = 91-60-1 反应条件:1.1 Reagents: 1,2-Ethanedithiol,Potassium Hydroxide Catalysts: Copper Sulfate Solvents: Dimethyl Sulfoxide,Water; 20 H,90 °C 标题:Copper(Ii)-Catalyzed Single-Step Synthesis Of Aryl Thiols From Aryl Halides And 1,2-Ethanedithiol 作者:Liu,Yajun; Kim,Jihye; Seo,Heesun; Park,Sunghyouk; Chae,Junghyun 参考文献:Advanced Synthesis & Catalysis 日期:2015 卷标:357(10) 页码:2205-2212]
62141-80-4 = 91-60-1 反应条件:1.1 Catalysts: Triphenylphosphine,Iodine Solvents: Benzene; Reflux 标题:Triphenylphosphine-Iodine 作者:Dormoy,Jean-Robert; Castro,Bertrand 参考文献:E-Eros Encyclopedia Of Reagents For Organic Synthesis 日期:2001]
93-11-8 = 91-60-1 反应条件:1.1 Reagents: Triphenylphosphine Solvents: Heptane; 85 °C; 1 H,85 °C; 85 °C -> 50 °C1.2 Reagents: Water; 10 Min,50 °C 标题:Preparation And Characterization Of Thiophenol Compounds 作者:Feng,Baicheng; Liu,Peng; Jing,Liqian 参考文献:Qingdao Keji Daxue Xuebao 日期:2011 卷标:32(3) 页码:252-255]
5586-15-2 = 91-60-1 反应条件:1.1 Reagents: Hydrogen Catalysts: Cobalt Solvents: Tetrahydrofuran 标题:Reduction Of Sulfonyl Chlorides To Thiols 作者:Mylroie,Victor L.; Doles,Joseph K. 参考文献:Chemical Industries (Dekker) 日期:1990 卷标:40 页码:189-96]
201036-12-6 = 91-60-1 反应条件:1.1 Solvents: Acetonitrile 标题:Photochemistry And Photophysics Of Aromatic Sulfoxides. 9. Photochemistry Of Benzyl β-Naphthyl Sulfoxide And Characterization Of The β-Naphthylsulfinyl Radical 作者:Guo,Yushen; Darmanyan,Alexandre P.; Jenks,William S. 参考文献:Tetrahedron Letters 日期:1997 卷标:38(50) 页码:8619-8622]
580-13-2 = 91-60-1 反应条件:1.1 Reagents: Ethanethiol,Sodium Hydride Solvents: Dimethylformamide; 0 °C; 30 Min,Rt1.2 Solvents: Dimethylformamide; 24 H,Reflux; Cooled1.3 Reagents: Hydrochloric Acid Solvents: Water 标题:Camphor-Based Schiff Base Of 3-Endo-Aminoborneol (Sbab): Novel Ligand For Vanadium-Catalyzed Asymmetric Sulfoxidation And Subsequent Kinetic Resolution 作者:Chuo,Ting Hung; Boobalan,Ramalingam; Chen,Chinpiao 参考文献:Chemistryselect 日期:2016 卷标:1(10) 页码:2174-2180]
607-53-4 = 91-60-1 反应条件:1.1 Catalysts: 1-Naphthalenethiol 标题:Aqueous High-Temperature Chemistry Of Carbo- And Heterocycles. Part 16. Model Sulfur Compounds: A Study Of Hydrogen Sulfide Generation 作者:Katritzky,Alan R.; Murugan,Ramiah; Balasubramanian,Marudai; Greenhill,John V.; Siskin,Michael; Et Al 参考文献:Energy & Fuels 日期:1991 卷标:5(6) 页码:823-34
专利号:WO-0142264-A1 优先权日:1999-12-10 标 题 :Method for the synthesis of sialylated oligosaccharide donors 发明人:MEHTA SEEMA; GILBERT MICHEL; WAKARCHUK WARREN W; WHITFIELD DENNIS M 权利人:CA NAT RESEARCH COUNCIL; MEHTA SEEMA; GILBERT MICHEL; WAKARCHUK WARREN W; WHITFIELD DENNIS M 摘要:A method for the synthesis of aryl thioglycosides comprising a sialylated residue of β-D-galactose is disclosed. The method consists of preparing by a chemical synthesis a non-sialylated aryl thioglycoside, and enzymatically sialylating the latter with a sialic acid in the presence of a suitable sialyltransferase. The sialylated aryl thioglycoside is then chemically derivatized by standard procedures, to provide a derivative suitable for use as a donor in chemical syntheses of sialylated oligosaccharides. The derivatized sialylated aryl thioglycosides are prepared in high yields, due to reduced number of chemical and purification steps involved in the process. Derivatized aryl thioglycosides useful as building blocks for the synthesis of biologically active sialylated oligosaccharides are also disclosed.
专利号:US-6184168-B1 优先权日:1997-09-22 标题:Synthesis of 1,4-trans-polybutadiene using a lanthanide organic acid salt catalyst 发明人:LYNCH THOMAS J 权利人:BRIDGESTONE CORP 摘要:The invention provides a catalyst composition, comprising: (a) an organolithium compound; and, (b) an organic acid salt of lanthanide series element; wherein: (1) only components (a) and (b) are required to promote the synthesis of 1,4-trans-polybutadiene; (2) the ratio of component (a) to component (b) is selected to maximize formation of the trans structure of said 1,4-trans-polybutadiene; and, (3) components (a) and (b) are selected for enabling further diblock synthesis. The invention further contemplates a process for using the catalyst to synthesize 1,4-trans-polybutadiene and other polymers and copolymers having trans configuration in the conjugated diene monomer contributed units.
专利号:US-10150160-B2 优先权日:2014-12-04 标题 :Universal one-pot and up-scalable synthesis of SERS encoded nanoparticles 发明人:PAZOS PÉREZ NICOLÃ?S; MIR DE SIMÓN BERNAT 权利人:MEDCOM ADVANCE S A; MEDCOM ADVANCE S A 摘要:The universal one-pot and up-scalable synthesis of SERS encoded nanoparticles relies on the controlled co-absorption of mercaptoundecanoic acid (MUA) and the Raman code on the metallic surfaces of the nanoparticles. In contrast to most of the reported procedures which typically involve complex steps, the present method has demonstrated to be an easy and fast one-pot approach for the production of SERS-encoded nanoparticles. This versatile strategy allows for the SERS codification of particles with every molecule with affinity toward the metal surface, independently of its chemical nature, as exemplified here in the fabrication of 31 different encoded particles using the same standard procedure. In addition to the easiness of preparation, scalability to the liter regime, stability in aqueous solutions including PBS and chemical diversity, our SERS-encoded particles show considerably higher optical efficiency than those fabricated by using PEG or PVP polymers.
专利号:US-9409945-B2 优先权日:1999-10-04 标 题 :Combinatorial synthesis of libraries of macrocyclic compounds useful in drug discovery 发明人:DESLONGCHAMPS PIERRE; DORY YVES; BERTHIAUME GILLES; OUELLET LUC; LAN RUOXI 权利人:OCERA THERAPEUTICS INC 摘要:A library of macrocyclic compounds of the formula (I) n n n n n n n n n n n n where part (A) is a n n n n n n n n n n n n n n n n  bivalent radical, a —(CH 2 ) y — bivalent radical or a covalent bond; n where part (B) is a n n n n n n n n n n n n n n n n  bivalent radical, a —(CH 2 ) z — bivalent radical, or a covalent bond; n where part (C) is a n n n n n n n n n n n n n n n n  bivalent radical, a —(CH 2 ) t — bivalent radical, or a covalent bond; and n where part (T) is a —Y-L-Z— radical wherein Y is CH 2 or CO, Z is NH or O and L is a bivalent radical. These compounds are useful for carrying out screening assays or as intermediates for the synthesis of other compounds of pharmaceutical interest. A process for the preparation of these compounds in a combinatorial manner, is also disclosed.
专利号:US-9908846-B2 优先权日:2014-02-21 标题:Composition, synthesis, and use of new arylsulfonyl isonitriles 发明人:FLEMING FRASER FERGUSSON; LUJAN MONTELONGO JESUS ARMANDO 权利人:DUQUESNE UNIV OF THE HOLY GHOST; UNIV HOLY GHOST DUQUESNE 摘要:This invention relates to novel isonitriles, including arylsulfonyl isonitriles, and methods for their synthesis. The isonitriles include a conjugated ring system. The structure is designed with the flexibility to have multiple substitution patterns. The isonitriles may be used in applications including, but not limited to, pharmaceutical compositions.
专利号:US-9815809-B2 优先权日:2013-07-05 标题:Formation of chiral 4-chromanones using chiral pyrrolidines in the presence of phenols or thiophenols 发明人:LETINOIS ULLA; NETSCHER THOMAS 权利人:DSM IP ASSETS BV 摘要:The present invention relates to a synthesis of chromanones or chromanes in a stereospecific matter in view of the 2-position in the chromanone or chromane ring. It has been found that this synthesis is particularly possible in the presence of a chiral compound of formula of a specific type and of at least one phenol or thiophenol.
参考标题:Copper-Mediated Direct Sulfenylation Of 4-Hydroxyquinolinones And 4-Hydroxypyridones With Aryl Thiols Via A C−h Functionalization Process 作者:Tao Guo,Hongyan Wang |发布日期:2017.9 摘要:An Efficient Approach For The Direct Sulfanylation Of 4-Hydroxyquinolinones And 4-Hydroxypyridones With Aryl Thiols In The Presence Of Cui/dmso Has Been Developed. The Substrate Scope Is Broad, Allowing Facile Synthesis Of A Range Of Structurally Diverse 3-Sulfanyl-4-Hydroxyquinolinones And 3-Sulfanyl-4-Hydroxypyridones In Good Efficiency.
合成参考文献
摘要:Yoshikai, N.; Rayner, C. M.; Graham, M. A., Science of Synthesis Knowledge Updates, (2020) 2, 75. 摘要:Sainsbury, M., Science of Synthesis Knowledge Updates, (2010) 1, 213. 摘要:Yoshimoto, F. K.; Li, Q., Science of Synthesis Knowledge Updates, (2012) 1, 248. 摘要:Podlech, J., Science of Synthesis Knowledge Updates, (2018) 4, 178. 摘要:Beier, P., Science of Synthesis Knowledge Updates, (2014) 2, 315.