CAS: 930-62-1; 2,4-Dimethylimidazole

• 英文名称2,4-Dimethylimidazole
• 中文名称2,4-二甲基咪唑
• IUPAC名称2,5-dimethyl-1H-imidazole
• 其它别名1H-咪唑,1-(2-丙烯基)-; 24二甲基咪唑; 2,5-Dimethyl-1H-Imidazole; 2,4-Dimethylimidazole
• CAS编号930-62-1
• MFCD编号:MFCD00022365
• EINECS号:213-221-4
• FDA UNII编号:T0MIX7SJ2E
• 分子式:C5H8N2
• 分子量:96.13
• 产品CID: 1969424
• 产品分类有机原料→分子砌块→芳杂环类化合物→咪唑类化合物

• 相似结构搜索
• InChIKey: LLPKQRMDOFYSGZ-UHFFFAOYSA-N
• InChI=1S/C5H8N2/c1-4-3-6-5(2)7-4/h3H,1-2H3,(H,6,7)…
• 计算化学: 氢键受体数1.0氢键供体数1.0可旋转键数0.0

相似化合物

物理性质

• 熔点85-87°C
• 沸点266 °C at 733 mmHg
• 闪点266°C
• 密度1.0±0.1 g/cm3
• pKa:8.36(at 25°C)
• PSA:28.68
• LogP:1.02654
• 折射率1.520
• 蒸汽压0.0±0.5 mmHg at 25°C
• 溶解性Soluble In Water.
• 敏感性常温常压下稳定，避免强氧化剂 酸接触
• 外观形态黄色至橙色弱块状物或粘稠液体
• 储存条件密封, 常温干燥保存
• 产品应用用作环氧树脂固化剂,可广泛用于环氧树脂粘接,涂装,浇注,包封,浸渍及复合材料等.
• 性质描述淡黄色或白色结晶.熔点91-81°C,沸点266°C

MSDS等安全信息

• GHS象形图
• GHS符号GHS05;
  注释: Corrosion
• 危险类别皮肤腐蚀 类别1B
  急性毒性 类别4(经口)
  皮肤腐蚀/刺激 类别2
  严重眼损伤 类别1
  皮肤腐蚀 类别1
• 警示词Danger(危险)
• 危险描述H314 |造成严重皮肤灼伤和眼损伤.
  H302 |吞咽有害.
  H315 |造成皮肤刺激.
  H318 |造成严重眼损伤.
• 防范说明P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
• 危险等级8
• UN编号3263.0
• 危险品标志C
• 包装等级Ⅲ
• 安全声明45-36/37/39-26
• 危险类别码34-22

欧盟法规

上下游产品

合成工艺路线路线简述

• 合成目标产物 2,4-Dimethylimidazole 主要起始原料 D(+)-Glucose And Acetaldehyde
• 2450-71-7 + 1000-84-6 = 930-62-1 [标题:Reaction Conditions
  标题:New Process For Synthesis Of Imidazole Derivatives
  作者:Eloy,F.; Deryckere,A.; Maffrand,J. P.
  参考文献:European Journal Of Medicinal Chemistry 日期:1974 卷标:9(6) 页码:602-6]
  
  83576-22-1 = 930-62-1
  反应条件:1.1 Reagents: Water Solvents: Water
  标题:A New Synthesis Of Imidazoles
  作者:Casey,Michael; Moody,Christopher J.; Rees,Charles W.
  参考文献:Journal Of The Chemical Society 日期:1982 卷标:(13) 页码:714-15]
  
  78-90-0 = 930-62-1
  反应条件:1.1 Catalysts: Ap 64K
  标题:Catalytic Synthesis Of C-Alkylimidazoles In The Presence Of Platinum/alumina Catalysts
  作者:Gitis,K. M.; Neumoeva,G. E.; Raevskaya,N. I.; Arutyunyants,G. A.; Isagulyants,G. V.
  参考文献:Izvestiya Akademi Nauk 日期:1992 卷标:(4) 页码:932-40]
  
  52726-31-5 = 930-62-1
  反应条件:1.1 Reagents: Triethylsilane Catalysts: Palladium Solvents: Tetrahydrofuran; 24 H,Rt
  标题:Deprotection Of N-Benzylbenzimidazoles And N-Benzylimidazoles With Triethylsilane And Pd/c
  作者:Graham,Thomas H.
  参考文献:Tetrahedron Letters 日期:2015 卷标:56(21) 页码:2688-2690]
  
  930-61-0 = 930-62-1
  反应条件:1.1 Catalysts: Chloroform
  标题:Reactions Of Halomethanes In The Vapor Phase. Part 5. The Reactions Of Imidazolines,Anils,And 1-Methylimidazole With Chloroform At 550°C,And A Comparison With Their Liquid-Phase Reactions With Trichloroacetate Ion Or Hexachloroacetone And Base
  作者:Busby,Reginald E.; Khan,Mohammad A.; Khan,Mohammad R.; Parrick,John; Shaw,C. J. Granville
  参考文献:Journal Of The Chemical Society 日期:1980 卷标:(7) 页码:1431-5]
  
  = 930-62-1 [标题:Reaction Conditions
  标题:Imidazoles
  参考文献:Japan]
  
  = 930-62-1 [标题:Reaction Conditions
  标题:An Approach To The Cyclopeptide Alkaloids (Phencyclopeptines) Via Heterocyclic Diamide/dipeptide Equivalents. Preparation And N-Alkylation Studies Of 2,4(5)-Disubstituted Imidazoles
  作者:Lipshutz,Bruce H.; Morey,Matthew C.
  参考文献:Journal Of Organic Chemistry 日期:1983 卷标:48(21) 页码:3745-50]
  
  = 930-62-1 [标题:Reaction Conditions
  标题:4-Methylimidazoles
  参考文献:European Patent Organization]
  
  = 930-62-1 [标题:Reaction Conditions
  标题:Imidazoles By Reaction Of Acetalated α-Dicarbonyl Compounds With Ammonia And/or Ammonium Salts And Aldehydes
  参考文献:Federal Republic Of Germany]
  
  = 930-62-1
  反应条件:1.1 Reagents: Nitrosonium Tetrafluoroborate,Vitride
  标题:Reductions By Metal Alkoxyaluminum Hydrides. Part Ii. Carboxylic Acids And Derivatives,Nitrogen Compounds,And Sulfur Compounds
  作者:Malek,Jaroslav
  参考文献:Organic Reactions (Hoboken 日期:1988 卷标:36]
  
  = 930-62-1 [标题:Reaction Conditions
  标题:Reaction Of Nitrosonium Fluoborate With Olefins In Nitrile Media. Two-Step Synthesis Of Imidazoles From Olefins
  作者:Scheinbaum,Monte L.; Dines,Martin B.
  参考文献:Tetrahedron Letters 日期:1971 卷标:(24) 页码:2205-8]
  
  83576-22-1 = 930-62-1 [标题:Reaction Conditions
  标题:Synthesis Of Imidazoles From Alkenes
  作者:Casey,Michael; Moody,Christopher J.; Rees,Charles W.
  参考文献:Journal Of The Chemical Society 日期:1984 卷标:(8) 页码:1933-41]
  
  592-20-1 = 930-62-1 [标题:Reaction Conditions
  标题:Product Class 3: Imidazoles
  作者:Grimmett,M. R.
  参考文献:Science Of Synthesis 日期:2002 卷标:12 页码:325-528]
  
  = 930-62-1
  反应条件:1.1 Reagents: Lithium Sulfide Solvents: Benzene,Acetonitrile,2-Amino-1-Butanol; 3 D,85 °C
  标题:Preparation Method Of Neutron Shielding Material Based On Metal Boron-Imidazole Framework
  参考文献:China]
  
  78-98-8 = 930-62-1
  反应条件:1.1 Reagents: Sodium Bicarbonate
  标题:Chemoselective And Living/controlled Polymerization Of Polar Divinyl Monomers By N-Heterocyclic Olefin Based Classical And Frustrated Lewis Pairs
  作者:Zhao,Wuchao; Wang,Qianyi; He,Jianghua; Zhang,Yuetao
  参考文献:Polymer Chemistry 日期:2019 卷标:10(31) 页码:4328-4335]
  
  78-98-8 = 930-62-1
  反应条件:1.1 Reagents: Ammonium Oxalate,Ammonia Solvents: Water; 3 H,45 °C; 2 H,45 °C
  标题:Process For Preparation Of Dialkyl Imidazole
  参考文献:China]
  
  83505-98-0 = 930-62-1
  反应条件:1.1 Solvents: Ethanol
  标题:Synthesis Of Some Alkyl- And Arylimidazoles
  作者:Watanabe,T.; Nishiyama,J.; Hirate,R.; Uehara,K.; Inoue,M.; Et Al
  参考文献:Journal Of Heterocyclic Chemistry 日期:1983 卷标:20(5) 页码:1277-81]
  
  = 930-62-1 [标题:Reaction Conditions
  标题:Manufacture Of Stable 2-Ethyl-4-Methylimidazole Compositions
  参考文献:Japan]
  
  = 930-62-1 [标题:Reaction Conditions
  标题:Method For The Preparation Of Imidazoles By Dehydrogenation Of Imidazolines
  参考文献:United States]
  
  = 930-62-1 [标题:Reaction Conditions
  标题:Preparation Of 4-Methylimidazoles From Methylglyoxal,Aldehydes,And Ammonia
  参考文献:Japan

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