CAS: 101-31-5; (S)-Atropine

上下游产品

CAS号51-34-3 东莨菪碱 | CAS号114-49-8 氢溴酸东莨菪碱 | CAS号16202-15-6 (S)-3-羟基-2-苯基丙酸 | CAS号120-29-6 托品醇; 品托碱 | CAS号74-88-4 碘甲烷 | CAS号3144-16-9 右旋樟脑磺酸 | CAS号51-55-8 阿托品； 颠茄碱 | CAS号529-64-6 托品酸 | CAS号120-29-6 托品醇; 品托碱 | CAS号16202-15-6 (S)-3-羟基-2-苯基丙酸 | CAS号5627-14-5 L-tropic acid-(... | CAS号500-55-0 阿朴阿托品

(-)-Littorine置于sodium (Rs)-Phenyl<2-(18)O,2-(2)H>Acetate,Datura Stramonium Root Cultures体系中,化学反应 264.0H,反应生成莨菪碱
参考文献:Tropic Acid Biosynthesis: The Incorporation Of (Rs)-Phenyl[2-18O,2-2H]Lactate Into Littorine And Hyoscyamine In Datura Stramonium
标题:Tropic Acid Biosynthesis: The Incorporation Of (Rs)-Phenyl[2-18O,2-2H]Lactate Into Littorine And Hyoscyamine In Datura Stramonium
摘要:在曼陀罗(datura Stramonium)中,从(rs)-苯基-[2-¹⁸o,2-²h]乳酸掺入到托品类生物碱毛鱼藤碱1和莨菪碱2的过程显示,在1转变为2的过程中,最多有29%的¹⁸o流失.
Doi:10.1039/a801722K

专利信息

专利号:WO-2013087821-A1
优先权日:2011-12-15
标题:Overproduction of jasmonates in transgenic plants
发明人：CHAMPION ANTONY
权利人:INST RECH DEVELOPPEMENT IRD
摘要:La present invention relates to the use of a nucleic sequence allowing the synthesis of Gh ERF-IIa, Gh ERF-IIb or Gh ERF-IIc in a plant in order to induce, in the plant, an overproduction or accumulation of jasmonic acid and/or OPDA. The accumulation of jasmonic acid and/or OPDA confers, in particular, to the transformed plant an improved resistance to bioagressors. The nucleic sequences, transformation methods and transformed plants according to the invention may also been used for the production of pharmaceutically important secondary metabolites whose synthesis is induced by jasmonates.

专利号:US-5110929-A
优先权日:1986-08-07
标题 :Process for the preparation of N-alkylated quaternary nitrogen containing aromatic heterocycles
发明人：PARADIES HENRICH H
权利人:MEDICE CHAM PHARM FABRIK PUTTE
摘要:The synthesis of 4-, 4-(1,1)-and 3,5-substituted N-alkyl-pyridinium salts as well as of 2-carboxamide substituted N(1,4)diazinium compounds are described. The N-surfactants obtained have a small critical micelle concentration (CMC) of 10-5 -10-7 Mol/Liter. These surfactants produce micells of different size and form depending on the nature of the anions. 4-(1,1)-substituted and 3,5-substituted N-alkyl-pyridinium components are capable of forming vesicles in equeous solutions of different forms and sizes. The N-surfactants synthesized can be used as pharmaceuticals.

专利号:US-5900227-A
优先权日:1996-06-17
标题 :Multicyclic nitrone spin trapping compositions
发明人：JANZEN EDWARD G; SANKURATRI NAGARAJU
权利人:OKLAHOMA MED RES FOUND
摘要:Multicyclic nitrone spin trapping compounds capable of forming stable free radical spin adducts are provided as well as methods for their synthesis. The multicyclic nitrone spin trapping compounds can be reacted with a free radical, such as a hydroxy or hydroperoxy radical, in solution to form a spin adduct which is stable and readily detectable by electron paramagnetic resonance (EPR) spectroscopy. The multicyclic nitrone spin traps can be used to detect free radicals in a sample such as a biological system. In one embodiment, the spin trapping compound, 1,3,3-trimethyl-6-azabicyclo-[3.2.1]oct-6-ene-N-oxide ('TRAZON') is provided, as well as methods for the synthesis of TRAZON and of modified forms of TRAZON. TRAZON can react with a wide range of different free radicals in solution to form free radical spin adducts which are readily detectable by EPR.

专利号:EP-0022434-B1
优先权日:1979-06-27
标题 :Catalysts for the production and transformation of natural products having their origin in higher plants, process for production of the catalysts, and use thereof
摘要:Biocatalysts for production or transformation of natural products having their origin in higher plants, are obtained by immobilization of whole cells, protoplasts, protoplasts with regenerated cell walls, hybride cells or cell complexes isolated from higher plants. The catalysts are used in continuous or discontinuous processes for production of natural products by de novo synthesis or by partial synthesis from precursors, or for transformation of natural products.

专利号:US-2006035327-A1
优先权日:2001-02-28
标题:Recombinant super-compound interferon and uses thereof
发明人：WEI GUANGWEN
权利人:WEI GUANGWEN
摘要:This invention provides a recombinant super-compound interferon (rSIFN-co) and its equivalent with changed spatial configuration, high efficacy and low side effects. Therefore, high dose of rSIFN-co may be used. One characteristic of rSIFN-co is its ability to inhibit the HBV DNA duplication and secretion of HBsAg and HBeAg in in vitro pharmacological studies. The cytotoxic effect of rSIFN-co is only one-eighth (â…›) of currently clinically available interferons but its anti-viral effect is approximately five to twenty (5-20) times higher, and when used in vivo it has a broader spectrum of clinical applications and longer biofeedback response. This invention further provides super-compound interferon or its equivalent, synthesis of artificial gene with codon preference which codes for said rSIFN-co and its equivalent, vector comprising said gene and appropriate expression system for expression of said rSIFN-co. Finally this invention provides the super-compound interferon (rSIFN-co) and its equivalent, a process to produce same and uses thereof.

专利号:US-9751877-B2
优先权日:2012-09-21
标题 :Substituted pyrido[1,2-a]pyrazines for the treatment of neurodegenerative and neurological disorders
发明人：PETTERSSON MARTIN YOUNGJIN; JOHNSON DOUGLAS SCOTT; SUBRAMANYAM CHAKRAPANI; O'DONNELL CHRISTOPHER JOHN; AM ENDE CHRISTOPHER WILLIAM; GREEN MICHAEL ERIC; PATEL NANDINI CHATURBHAI; STIFF CORY MICHAEL; TRAN TUAN PHONG; KAUFFMAN GREGORY WAYNE; STEPAN ANTONIA FRIEDERIKE; VERHOEST PATRICK ROBERT
权利人:PFIZER
摘要:Compounds and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula I n nas defined in the specification. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.