专利号:US-2012108828-A1 优先权日:2010-09-09 标题 :Synthesis of dronedarone and salts thereof 发明人:SATHE DHANANJAY GOVIND; PATIL SAMADHAN DAULAT; GAIKWAD UMESH DILIP; RAO MANTRIPRAGADA NARAYANA; SHINDE AJIT BHASKAR 权利人:SATHE DHANANJAY GOVIND; PATIL SAMADHAN DAULAT; GAIKWAD UMESH DILIP; RAO MANTRIPRAGADA NARAYANA; SHINDE AJIT BHASKAR; USV LTD B S D MARG 摘要:The present invention relates to a process for preparation of Dronedarone or pharmaceutically acceptable salts thereof. More particularly, the present invention provides a process for preparation of Dronedarone hydrochloride, without the isolation of Dronedarone base.
专利号:US-8536350-B2 优先权日:2010-02-23 标 题:Process for the manufacture of dronedarone 发明人:SADA MARA; NARDI ANTONIO; MAIORANA STEFANO 权利人:SADA MARA; NARDI ANTONIO; MAIORANA STEFANO; LABORATORIO CHIMICO INT SPA 摘要:The invention relates to a new process for the preparation of dronedarone and its salts, in particular a synthesis process which allows said compound and its salts to be obtained with good yields, high purity and in an industrially expedient manner; the invention also concerns a new synthesis intermediate.
专利号:US-6828448-B2 优先权日:2000-12-11 标 题:Methanesulphonamido-benzofuran, preparation method and use thereof as synthesis intermediate 发明人:FINO NOEL; LEROY CORINNE 权利人:SANOFI SYNTHELABO 摘要:The invention relates to 2-butyl-5-(methanesulfonamido)benzofuran, its preparation and its use. n This compound is a synthesis intermediate, in particular for the preparation of dronedarone.
专利号:US-8779201-B2 优先权日:2007-10-02 标题 :Process for preparing benzofurans 发明人:EKLUND LARS 权利人:CAMBREX KARLSKOGA AB 摘要:There is provided a process for the preparation of a compound of formula (I), wherein R 1 , R 2 , R 3 , R 4 , X and Y are as described in the description. Such compounds may, for example, be useful intermediates in the synthesis of drugs such as Dronedarone.
专利号:EP-2428511-A1 优先权日:2010-09-09 标 题:Synthesis of dronedarone and salts thereof
专利号:CN-102659726-B 优先权日:2012-03-30 标题:Method for synthesis of dronedarone
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