CAS: 1942-52-5; 2-Diethylaminoethanethiol Hydrochloride

上下游产品

CAS号100-35-6 N,N-二乙基氯乙胺 | CAS号55297-95-5 泰妙菌素 | CAS号589-32-2 四乙基胱胺-13C4

N,N-二乙基氯乙胺置于盐酸体系中,用 乙醇,水 用作溶剂,化学反应 6.5H,反应生成2-二乙氨基乙硫醇盐酸盐
参考文献:Russo; Santagati; Venturini,Pharmazie,1990,Vol. 45,# 7,P. 493-495
标题:Russo; Santagati; Venturini,Pharmazie,1990,Vol. 45,# 7,P. 493-495

专利信息

专利号:WO-2014128524-A1
优先权日:2013-02-19
标题:An improved process for preparation of an intermediate of the pyrrolidine substituted flavones
发明人：CHENNAMSETTY SUNEELMANOHARBABU; PATIL RAJENDRA; HAREL PRASHANT; HARIHARAN SIVARAMAKRISHNAN
权利人:PIRAMAL ENTPR LTD
摘要:The present invention relates to a process for the preparation of a key intermediate (as described herein) used in the synthesis of (+)- trans enantiomer of pyrrolidine substituted flavones, represented by the compounds of formula (1) or pharmaceutically acceptable salts thereof; which are inhibitors of cyclin dependant kinases (CDKs) and can be used in the treatment of proliferative disorders such as cancer. Formula (1) wherein R 1 has the meaning as indicated in the claims. The process of the present invention has advantages of higher yield and purity, lower reaction temperature, is consistent and involves the use of non toxic solvents. The process of the present invention allows efficient large-scale synthesis and purity of the product obtained is greater than 97 %.

专利号:WO-2014128523-A1
优先权日:2013-02-19
标 题 :A process for preparation of an intermediate of the pyrrolidine substituted flavones
发明人：CHENNAMSETTY SUNEELMANOHARBABU; BOKKA RAVISHANKAR; VEERAPPAN RATHINASAMI; SIVAKUMAR MEENAKSHI; HARIHARAN SIVARAMAKRISHNAN
权利人:PIRAMAL ENTPR LTD
摘要:The present invention relates to a process for the preparation of a key intermediate (as described herein) used in the synthesis of (+)- trans enantiomer of pyrrolidine substituted flavones, represented by the compounds of formula (1) or pharmaceutically acceptable salts thereof; which are inhibitors of cyclin dependant kinases (CDKs) and can be used in the treatment of proliferative disorders such as cancer. Formula (1) wherein R has the meaning as indicated in the claims. The process of the present invention has advantages of higher yield and purity, lower reaction temperature, is consistent and involves the use of non toxic solvents. The process of the present invention allows efficient large-scale synthesis and purity of the product obtained is greater than 97 %.

专利号:US-2008242877-A1
优先权日:2007-02-26
标题 :Intermediates and processes for the synthesis of Ramelteon
发明人：KANSAL VINOD KUMAR; MISTRY DHIRENKUMAR N; VASOYA SANJAY L
权利人:KANSAL VINOD KUMAR; MISTRY DHIRENKUMAR N; VASOYA SANJAY L
摘要:Provided are intermediates and processes for preparation of Ramelteon.

专利号:US-2018208555-A1
优先权日:2013-11-18
标题 :Method of synthesis of an ionizable cationic lipid

专利号:US-10781169-B2
优先权日:2013-11-18
标 题:Method of synthesis of an ionizable cationic lipid

专利号:US-2021002217-A1
优先权日:2013-11-18
标题:Method of synthesis of an ionizable cationic lipid