CAS: 3724-10-5; 2-(Methylthio)Benzoic Acid

该化合物是一种芳香的碳酸,其特点是,在与碳酸酸功能组(COOH)相对的第二个位置,附于苯乙烯环的第二个位置上有一个甲基硫基(-S-CH3),该化合物一般是白色的,在有机溶剂中可溶解,而其溶解于水中的溶解性则因甲基硫酸组的疏水性而受到限制;甲基硫酸和氨基酸组的出现具有独特的化学再活性,使其在各种有机合成应用中有用;它可以参加典型的酸基反应,其甲基硫酸组可以进行核分裂替代或氧化反应.此外,2-(甲基乙基)苯甲酸可能展示生物活动,这在药物研究中可能有意义.适当的处理和储存与许多有机化合物一样,对于确保安全和稳定至关重要.

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CAS号147-93-3 硫代水杨酸 | CAS号74-88-4 碘甲烷 | CAS号865-33-8 甲醇钾 | CAS号124-38-9 二氧化碳 | CAS号19614-16-5 2-溴茴香硫醚 | CAS号86065-02-3 4,4-dimethyl-2-... | CAS号624-92-0 二甲基二硫醚 | CAS号65-85-0 苯甲酸 | CAS号616-38-6 碳酸二甲酯 | CAS号19093-34-6 2-(甲基亚磺酰)苯甲酸 | CAS号33963-55-2 2-甲砜基苯甲酸 | CAS号1442-03-1 2-methylsulfany... | CAS号1442-00-8 Benzoic acid,2-... | CAS号3704-28-7 2-(甲硫基)苯甲酸甲酯 | CAS号492-22-8 噻吨-9-酮 | CAS号67373-13-1 2-phenylsulfany... | CAS号5395-89-1 2-甲砜基苯甲醛 | CAS号6609-54-7 2-(甲基硫代)苯甲腈 | CAS号7022-45-9 2-(甲硫基)苯甲醛 | CAS号520-72-9 3-羟基苯并噻吩

合成工艺路线路线简述

    O-Carboxybenzenediazonium 反应生成 2-(甲基硫代)苯甲酸
    参考文献:De203388
    标题:De203388

    海关参考信息

    专利信息


    专利号:US-8202985-B2
    优先权日:2005-10-31
    标 题:Monomer compositions for the synthesis of polynucleotides, methods of synthesis, and methods of deprotection
    发明人:DELLINGER DOUGLAS J; TIMAR ZOLTAN; SIERZCHALA AGNIESZKA; DELLINGER GERALDINO; CARUTHERS MARVIN H
    权利人:DELLINGER DOUGLAS J; TIMAR ZOLTAN; SIERZCHALA AGNIESZKA; DELLINGER GERALDINO; CARUTHERS MARVIN H; AGILENT TECHNOLOGIES INC; UNIV COLORADO
    摘要:Nucleotide monomers, polynucleotides, methods of making each, and methods of deprotecting each, are disclosed. An embodiment of the nucleotide monomer, among others, includes a nucleotide monomer having a heterobase protecting group selected from structures I through III as described herein. An embodiment of the polynucleotide, among others, includes a plurality of nucleotide moieties having a heterobase protecting group selected from one of structures I through III as described herein.

    专利号:US-7759471-B2
    优先权日:2005-10-31
    标题 :Monomer compositions for the synthesis of RNA, methods of synthesis, and methods of deprotection
    发明人:DELLINGER DOUGLAS J; TIMAR ZOLTAN; SIERZCHALA AGNIESZKA; DELLINGER GERALDINE; CARUTHERS MARVIN H
    权利人:AGILENT TECHNOLOGIES INC; UNIV COLORADO
    摘要:Nucleotide monomers, polynucleotides, methods of making each, methods of deprotecting each, and the like are disclosed herein.

    专利号:US-6281391-B1
    优先权日:1998-10-27
    标 题 :Synthesis of methylthiophenyl hydroxyketones
    发明人:TILLYER RICHARD D; DAVIES IAN W; LARSEN ROBERT D; WANG XIN; O'SHEA PAUL; KING ANTHONY ON-PING; ZHAO DALIAN; CHEN CHENG Y; GRABOWSKI EDWARD J J
    权利人:MERCK & CO INC; MERCK FROSST CANADA INC
    摘要:This invention encompasses a novel process for synthesizing compounds represented by formula A: n These compounds are intermediates useful in the preparation of certain agents that are selective COX-2 inhibitors.

    专利号:US-2007100138-A1
    优先权日:2005-10-31
    标题:Monomer compositions for the synthesis of polynucleotides, methods of synthesis, and methods of deprotection

    专利号:US-2007100136-A1
    优先权日:2005-10-31
    标题:Monomer compositions for the synthesis of RNA, methods of synthesis, and methods of deprotection

    专利号:EP-2001896-A2
    优先权日:2006-03-23
    标 题 :Monomer compositions for the synthesis of rna, methods of synthesis, and methods of deprotection
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    合成参考文献


    摘要:Grogan, G., Science of Synthesis: Biocatalysis in Organic Synthesis, (2015) 3, 294.
    摘要:Kaneda, K.; Mitsudome, T., Science of Synthesis: Catalytic Reduction in Organic Synthesis, (2017) 1, 339.
    摘要:Xu, L., Science of Synthesis: Advances in Organoboron Chemistry towards Organic Synthesis, (2019) 1, 273.
    摘要:Bulletin de la Societe Royale des Sciences de Liege., 47(202), 1978
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