专利号:US-8202985-B2 优先权日:2005-10-31 标 题:Monomer compositions for the synthesis of polynucleotides, methods of synthesis, and methods of deprotection 发明人:DELLINGER DOUGLAS J; TIMAR ZOLTAN; SIERZCHALA AGNIESZKA; DELLINGER GERALDINO; CARUTHERS MARVIN H 权利人:DELLINGER DOUGLAS J; TIMAR ZOLTAN; SIERZCHALA AGNIESZKA; DELLINGER GERALDINO; CARUTHERS MARVIN H; AGILENT TECHNOLOGIES INC; UNIV COLORADO 摘要:Nucleotide monomers, polynucleotides, methods of making each, and methods of deprotecting each, are disclosed. An embodiment of the nucleotide monomer, among others, includes a nucleotide monomer having a heterobase protecting group selected from structures I through III as described herein. An embodiment of the polynucleotide, among others, includes a plurality of nucleotide moieties having a heterobase protecting group selected from one of structures I through III as described herein.
专利号:US-7759471-B2 优先权日:2005-10-31 标题 :Monomer compositions for the synthesis of RNA, methods of synthesis, and methods of deprotection 发明人:DELLINGER DOUGLAS J; TIMAR ZOLTAN; SIERZCHALA AGNIESZKA; DELLINGER GERALDINE; CARUTHERS MARVIN H 权利人:AGILENT TECHNOLOGIES INC; UNIV COLORADO 摘要:Nucleotide monomers, polynucleotides, methods of making each, methods of deprotecting each, and the like are disclosed herein.
专利号:US-6281391-B1 优先权日:1998-10-27 标 题 :Synthesis of methylthiophenyl hydroxyketones 发明人:TILLYER RICHARD D; DAVIES IAN W; LARSEN ROBERT D; WANG XIN; O'SHEA PAUL; KING ANTHONY ON-PING; ZHAO DALIAN; CHEN CHENG Y; GRABOWSKI EDWARD J J 权利人:MERCK & CO INC; MERCK FROSST CANADA INC 摘要:This invention encompasses a novel process for synthesizing compounds represented by formula A: n These compounds are intermediates useful in the preparation of certain agents that are selective COX-2 inhibitors.
专利号:US-2007100138-A1 优先权日:2005-10-31 标题:Monomer compositions for the synthesis of polynucleotides, methods of synthesis, and methods of deprotection
专利号:US-2007100136-A1 优先权日:2005-10-31 标题:Monomer compositions for the synthesis of RNA, methods of synthesis, and methods of deprotection
专利号:EP-2001896-A2 优先权日:2006-03-23 标 题 :Monomer compositions for the synthesis of rna, methods of synthesis, and methods of deprotection
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