CAS: 6146-52-7; 5-Nitroindole

上下游产品

CAS号6625-96-3 5-硝基吲哚-3-甲醛 | CAS号17422-32-1 5-氯吲哚 | CAS号125600-42-2 2-乙炔-4-硝基苯胺 | CAS号166104-19-4 5-硝基-1H-吲哚-1-甲酸叔丁酯 | CAS号32692-19-6 5-硝基吲哚啉 | CAS号32685-24-8 1-(4-methylphen... | CAS号503534-46-1 4-nitro-2-[(tri... | CAS号6293-83-0 2-碘-4-硝基苯胺 | CAS号10075-50-0 5-溴吲哚 | CAS号88-12-0 N-乙烯基吡咯烷酮 | CAS号106516-27-2 3-(1-甲基-1,2,3,6... | CAS号106515-92-8 1-(4-fluorophen... | CAS号107754-14-3 4-(5-Amino-1-me... | CAS号32692-19-6 5-硝基吲哚啉 | CAS号3414-64-0 N,N-二甲基-5-硝基色胺 | CAS号29906-67-0 1-甲基-5-硝基吲哚 | CAS号91482-63-2 1-甲基-4-硝基-1H-吲哚 | CAS号193977-99-0 1-ethyl-5-nitro... | CAS号226901-50-4 (5-硝基-1H-吲哚-1-基)乙酸 | CAS号220844-49-5 (9ci)-1-乙基-1H-吲哚-5-胺

1-乙酰基-5-硝基二氢吲哚置于盐酸,四氯苯醌,Xylene体系中,化学反应生成 5-硝基吲哚
参考文献:Terent'Ew Et Al.,Zhurnal Obshchei Khimii,1959,Vol. 29,P. 2541,2550; Engl. Ausg. S. 2504,2511
标题:Terent'Ew Et Al.,Zhurnal Obshchei Khimii,1959,Vol. 29,P. 2541,2550; Engl. Ausg. S. 2504,2511

专利信息

专利号:US-2005130201-A1
优先权日:2003-10-14
标 题 :Splint-assisted enzymatic synthesis of polyribounucleotides
发明人：DERAS MICHAEL; PLEISS JEFFREY A; SCARINGE STEPHEN
权利人:DHARMACON INC
摘要:The present invention comprises methods and compositions for splint-assisted enzymatic synthesis of polyribonucleotides using an RNA polymerizing enzyme. The invention provides ligating ribonucleotides comprising ligating a donor RNA molecule to an acceptor RNA molecule in the presence of RNA ligase and a splint, wherein the donor RNA molecule is comprised of at least one nucleotide and a ligation linker moiety, the acceptor RNA molecule is comprised of at least one nucleotide and a ligation linker moiety and the splint is comprised of a polyribonucleotide. The invention also provides splints for use in splint-assisted enzymatic synthesis using an RNA polymerizing enzyme.

专利号:US-6022963-A
优先权日:1995-12-15
标 题:Synthesis of oligonucleotide arrays using photocleavable protecting groups
发明人：MCGALL GLENN H; NAM NGO QUOC
权利人:AFFYMETRIX INC
摘要:Novel compounds are provided which are useful as linking groups in chemical synthesis, preferably in the solid phase synthesis of oligonucleotides and polypeptides. These compounds are generally photolabile and comprise protecting groups which can be removed by photolysis to unmask a reactive group. The protecting group has the general formula Ar-C(R1)(R2)-O-C(O)- wherein: Ar is an optionally substituted fused polycyclic aryl or heteroaromatic group or a vinylogous derivative thereof; R1 and R2 are independently H, optionally substituted alkyl, alkenyl or alkynyl, optionally substituted aryl or optionally substituted heteroaromatic, or a vinylogous derivative of the foregoing; and X is a leaving group, a chemical fragment linked to Ar-C(R1)(R2)-O-C(O)- via a heteroatom, or a solid support; provided that when Ar is 1-pyrenyl and R1=R2=H, X is not linked to Ar-C(R1)(R2)-O-C(O)- via a nitrogen atom. Preferred embodiments are those in which Ar is a fused polycyclic aromatic hydrocarbon and in which the substituents on Ar, R1 and R2 are electron donating groups. A particularly preferred protecting group is the 'PYMOC' protecting group, pyrenylmethyloxycarbonyl, where Ar=pyrenyl and R1=R2=H. Also provided is a method of forming, from component molecules, a plurality of compounds on a support, each compound occupying a separate predefined region of the support, using the protected compounds described above.

专利号:US-11858953-B2
优先权日:2018-04-04
标 题:Compositions and methods for synthesis of phosphorylated molecules
发明人：CHAPUT JOHN; LIAO JEN-YU; BALA SAIKAT
权利人:UNIV CALIFORNIA
摘要:The invention provides compositions and methods for synthesis of phosphorylated organic compounds, including nucleoside triphosphates.

专利号:US-11414687-B2
优先权日:2017-10-04
标题:Method and system for enzymatic synthesis of oligonucleotides
发明人：HOFF KENDALL; HALPAIN MICHELLE; GARBAGNATI GIANCARLO; ZHOU WEI
权利人:CENTRILLION TECH HOLDINGS CORP
摘要:The present disclosure relates to methods, processes and systems for enzymatic synthesis of oligonucleotide from a single-stranded, immobilized primer in the presence of a polymerase. Using the disclosed methods single-stranded oligonucleotides can be synthesized enzymatically from a single-stranded, immobilized primer in the presence of deoxyribonucleotide triphosphates or ribonucleotide triphosphates. Dideoxyribonucleotide triphosphates, deoxyribonucleotide triphosphates with reversible terminators, or ribonucleotide triphosphates with reversible terminators can be added enzymatically to the end of the primer or its extension products. According to the disclosed method, a single-stranded primer can bind to a template such that the thus-formed double-stranded structure can allow the polymerase to extend the primer at 3′ end.

专利号:US-2023212204-A1
优先权日:2020-01-16
标题:Reagents and their use for modular enantiodivergent synthesis of c-p bonds
发明人：XU DONGMIN; RIVAS-BASCÓN NAZARET; KNOUSE KYLE W; PADIAL NATALIA; ZHENG BIN; VANTOUROUT JULIEN; SCHMIDT MICHAEL; EASTGATE MARTIN D; BARAN PHI
权利人:BRISTOL MYERS SQUIBB CO; SCRIPPS RESEARCH INST
摘要:The disclosure describes chiral P(V)-based reagents and their uses for the modular, scalable, and stereospecific synthesis of chiral phosphines, phosphine oxides and particular oligonucleotides.

专利号:US-2023323449-A1
优先权日:2021-12-17
标 题:Compositions and methods for detection of variants
发明人：GANTT RICHARD; ARNESON ADRIANA
权利人:TWIST BIOSCIENCE CORP
摘要:Testing the many hypotheses from genomics and systems biology experiments demands accurate and cost-effective gene and genome synthesis. Here we describe a microchip-based technology for multiplex gene synthesis. Pools of thousands of ‘construction’ oligonucleotides and tagged complementary ‘selection’ oligonucleotides are synthesized on photo-programmable microfluidic chips, released, amplified and selected by hybridization to reduce synthesis errors ninefold. A one-step polymerase assembly multiplexing reaction assembles these into multiple genes. This technology enabled us to synthesize all 21 genes that encode the proteins of the Escherichia coli 30S ribosomal subunit, and to optimize their translation efficiency in vitro through alteration of codon bias. This is a significant step towards the synthesis of ribosomes in vitro and should have utility for synthetic biology in general.