CAS: 94-71-3; 2-Ethoxyphenol

• 英文名称2-Ethoxyphenol
• 中文名称2-乙氧基苯酚
• IUPAC名称2-ethoxyphenol
• 其它别名邻苯二酚单乙基醚; 2乙氧基酚; Guaethol; Guethol; Nsc 180
• CAS编号94-71-3
• MFCD编号:MFCD00002187
• EINECS号:202-358-5
• FDA UNII编号:878IW8P9PW
• 分子式:C8H10O2
• 分子量:138.16
• 产品CID: 1999252
• 产品分类有机原料→分子砌块→芳环类化合物→苯类化合物

• 相似结构搜索
• InChIKey: MOEFFSWKSMRFRQ-UHFFFAOYSA-N
• InChI=1S/C8H10O2/c1-2-10-8-6-4-3-5-7(8)9/h3-6,9H,2H2,1H3…
• 计算化学: 氢键受体数2.0氢键供体数1.0可旋转键数2.0

物理性质

• 熔点20-25 °C
• 沸点216-217 °C at 760 mmHg
• 闪点91°C
• 密度1.1±0.1 g/cm3
• pKa:pK1:10.109 (25°C)
• PSA:29.46
• LogP:1.7909
• 折射率1.527
• 蒸汽压0.1±0.4 mmHg at 25°C
• 溶解性9G/l
• 敏感性避免与氧化物接触。
• 外观形态透明无色至黄色液体
• 储存条件存储低于 +30°C.
• 产品应用该化合物用于碳和能源补充剂.
• 性质描述密度1.09,熔点20-25°C,沸点216-217°C,折射率1.528-1.53,闪点91°C,完全无色透明液体,冬天可结成无色透明晶体.

MSDS等安全信息

• GHS象形图
• GHS符号GHS05 & GHS07;
  注释: Corrosion & Exclamation mark
• 危险类别严重眼损伤 类别1
  皮肤致敏 类别1
  水生慢性毒性 类别3
  急性毒性 类别4(经口)
  特定目标器官毒性 - 单次接触 类别3
  皮肤腐蚀/刺激 类别2
  严重眼刺激 类别2
  易燃液体 类别4
• 警示词Danger(危险)
• 危险描述H318 |造成严重眼损伤.
  H317 |可能引起皮肤过敏反应.
  H412 |对水生生物有害并具有长期持续影响.
  H302 |吞咽有害.
  H335 |可能引起呼吸道刺激.
  H315 |造成皮肤刺激.
  H319 |造成严重眼刺激.
  H227 |可燃液体
• 防范说明P210-P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P370+P378-P403-P405-P501
• 危险等级8
• UN编号1759.0
• 危险品标志Xn
• 包装等级Ⅲ
• 安全声明26-36/37/39-37/39
• 危险类别码22-37/38-41
• WGK Germany3

欧盟法规

上下游产品

合成工艺路线路线简述

• 合成目标产物 2-Ethoxyphenol 主要起始原料 3-Ethoxysalicylaldehyde
• 492-88-6 = 94-71-3
  反应条件:1.1 Catalysts: Ruthenium Trichloride,Rhodium Oxide (Rh2O3); 4 H,Rt -> 150 °C
  标题:Preparation Method Of O-Ethoxyphenol From O-Ethyl Vanillin
  参考文献:China]
  
  613-69-4 = 94-71-3
  反应条件:1.1 Reagents: Hydrogen Peroxide,Bis(2-Nitrophenyl) Diselenide Solvents: Dichloromethane,Water; 20 H,25 °C
  标题:The Baeyer-Villiger Oxidation Of Ketones And Aldehydes
  作者:Krow,Grant R.
  参考文献:Organic Reactions (Hoboken 日期:1993 卷标:43]
  
  613-69-4 = 94-71-3
  反应条件:1.1 Reagents: Hydrogen Peroxide Catalysts: Bis(2-Nitrophenyl) Diselenide Solvents: Dichloromethane,Water1.2 Reagents: Potassium Hydroxide Solvents: Methanol
  标题:The Baeyer-Villiger Oxidation Of Aromatic Aldehydes And Ketones With Hydrogen Peroxide Catalyzed By Selenium Compounds. A Convenient Method For The Preparation Of Phenols
  作者:Syper,Ludwik
  参考文献:Synthesis 日期:1989 卷标:(3) 页码:167-72]
  
  = 94-71-3
  反应条件:1.1 Reagents: Sodium Hydroxide Solvents: Ethanol,Polyethylene Glycol; Heated1.2 1 H,65 °C; 3.5 H,65 °C1.3 Reagents: Hydrogen Ion Solvents: Water; Ph 3; Cooled
  标题:Study On Synthesis Of Perfume Intermediate O-Ethoxyphenol
  作者:Zhang,Li-Qiong; Ji,Mu-Ge; Wu,Bin; Du,Run-Ping; Chai,Duo-Li
  参考文献:Jingxi Yu Zhuanyong Huaxuepin 日期:2006 卷标:14(24) 页码:23-25]
  
  274-09-9 = 94-71-3
  反应条件:1.1 Reagents: Sulfuric Acid
  标题:Reaction Of Substituted Benzodioxoles With Methylmagnesium Iodide Under Heterogeneous Conditions
  作者:Beltrame,Paolo; Gelli,Gioanna; Lai,Adolfo; Monduzzi,Maura
  参考文献:Journal Of Organic Chemistry 日期:1976 卷标:41(3) 页码:580-1]
  
  = 94-71-3
  反应条件:1.1 Reagents: Sulfuric Acid Solvents: Water; Rt -> 80 °C; 30 Min,80 °C; 80 °C -> 18 °C1.2 Reagents: Sodium Nitrite Solvents: Water; 18 °C1.3 Reagents: Sulfuric Acid,Copper Sulfate Solvents: Toluene,Water; 87 °C
  标题:Synthesis Of Ethyl Guaiacol
  作者:Lu,Xiao-Lan; Feng,Xue-Feng; Guo,Hui; Hu,Yu; Guo,Ying; Et Al
  参考文献:Jiangxi Shifan Daxue Xuebao 日期:2007 卷标:31(6) 页码:580-583]
  
  = 94-71-3
  反应条件:1.1 Reagents: Sodium Hydroxide Solvents: Water; 140 - 145 °C; 145 °C -> 165 °C; 160 - 165 °C
  标题:Pilot Synthesis Study Of O-Ethoxyphenol By Alkylation Of 1,2-Dihydroxybenzene
  作者:Yuan,Bing; Wang,Li-Fang; Sheng,Guang; Chen,Ji-Xin; Wang,Fang
  参考文献:Huagong Keji 日期:2005 卷标:13(4) 页码:32-34]
  
  = 94-71-3
  反应条件:1.1 Reagents: Sodium Carbonate,Sodium Hydroxide Catalysts: Polyethylene Glycol Solvents: Water
  标题:Synthesis Of 2-Ethoxyphenol Catalyzed By Phase Transfer Catalysts
  作者:Zhang,Zhenming
  参考文献:Huagong Shikan 日期:2000 卷标:14(12) 页码:54-56]
  
  90-05-1 = 94-71-3 + 120-95-6 + 1620-98-0 + 1020-31-1 + 4130-42-1 + 876-20-0 + 2934-05-6 + 5076-72-2 + 59056-76-7 + 52417-48-8 + 33963-27-8 + 87-97-8 + 79-74-3 + 2050-46-6
  反应条件:1.1 Catalysts: Tungstic Acid (H2Wo4); Rt -> 300 °C; 6 H,300 °C
  标题:Highly Selective Conversion Of Guaiacol To Tert-Butylphenols In Supercritical Ethanol Over A H2Wo4 Catalyst
  作者:Mai,Fuhang; Et Al
  参考文献:Rsc Advances 日期:2019 卷标:9(5) 页码:2764-2771]
  
  = 94-71-3
  反应条件:1.1 Catalysts: Hydroxylapatite (Ca5(Oh)(Po4)3); 5 H,230 °C -> 450 °C
  标题:Preparation Method Of Catechol Monoethyl Ether From Catechol And Diethyl Carbonate By Gas-Solid Reaction In Presence Of Hydroxyapatite As Catalyst
  参考文献:China]
  
  = 94-71-3
  反应条件:1.1 Catalysts: Zirconium Dioxide,Titanium Tetrabutoxide,Titania,Zirconium Oxychloride Octahydrate,Phosphate; 5 H,200 °C
  标题:Process For The Preparation Of 2-Ethoxyohenol
  参考文献:China]
  
  = 94-71-3
  反应条件:1.1 Reagents: Potassium Carbonate,Sodium Hydroxide Solvents: Toluene,Water; 5 Min,Rt1.2 Rt; 5 H,Rt -> 140 °C; 140 °C -> Rt1.3 Reagents: Hydrochloric Acid Solvents: Water; Ph 2 - 3
  标题:Method For Preparing O-Hydroxy Phenyl Alkyl Ethers From Catechol
  参考文献:China]
  
  = 94-71-3
  反应条件:1.1 Reagents: Sodium Hydroxide Catalysts: Benzenemethanaminium,N-Methyl-N,N-Dioctadecyl-,Chloride (1:1) Solvents: Ethanol,Toluene,Water; 60 °C; 3 H,60 °C
  标题:Study On Synthesis Of Drug Intermediate O-Ethoxyphenol By Phase Transfer Catalysis
  作者:Shu,Xue-Jun; Yin,Xu-Guang; Yang,Long; Wang,Bo; Sun,Qing; Et Al
  参考文献:Huaxue Shijie 日期:2012 卷标:53(2) 页码:95-97]
  
  274-09-9 + 91589-77-4 = 94-71-3 [标题:Reaction Conditions
  标题:Cleavage Of The Ether Bond. X. The Action Of Organocalcium Halides On 1,3-Benzoxathiole And 1,3-Benzodioxole Derivatives
  作者:Cabiddu,S.; Melis,S.; Marongiu,E.; Piras,P. P.; Podda,G.
  参考文献:Journal Of Organometallic Chemistry 日期:1976 卷标:111(3) 页码:249-55]
  
  2979-26-2 = 94-71-3
  反应条件:1.1 Reagents: Sodium Carbonate,Potassium Hydroxide Catalysts: Palladium; 2 H,320 °C
  标题:Process For Preparation Of O-Alkoxyphenol By Dehydrogenation Of O-Alkoxycyclohexanol
  参考文献:China]
  
  = 94-71-3
  反应条件:1.1 Reagents: Sodium Bicarbonate Catalysts: Potassium Iodide Solvents: Ethanol; 20 H,70 °C
  标题:Study On Synthesis Of Guaethol
  作者:Cheng,Wenfeng; Zhang,Wenjun; Ren,Chunhe; Xu,Xiaodong; Chen,Meifang
  参考文献:Henan Huagong 日期:2011 卷标:28(2) 页码:39-41]
  
  = 94-71-3
  反应条件:1.1 Reagents: Sodium Bicarbonate Catalysts: Potassium Iodide Solvents: Ethanol; 20 H,70 °C
  标题:Synthesis Of Guethol
  作者:Cheng,Wen-Feng; Zhang,Wen-Jun; Ren,Chun-He; Xu,Xiao-Dong; Chen,Mei-Fang
  参考文献:Zhejiang Huagong 日期:2011 卷标:42(2) 页码:8-10]
  
  = 94-71-3
  反应条件:1.1 Reagents: Phosphorus Pentoxide,Alumina,Silica Catalysts: Titania
  标题:O-Ethylation Of Catechol With Ethanol On Al-P-Ti-Si-O Catalyst
  作者:Li,Xue-Mei; Zhang,Wen-Xiang; Zhu,Xiao-Mei; Pan,Chun-Liu; Jiang,Da-Zhen; Et Al
  参考文献:Gaodeng Xuexiao Huaxue Xuebao 日期:2002 卷标:23(8) 页码:1552-1555]
  
  = 94-71-3
  反应条件:1.1 Reagents: Sodium Hydroxide Catalysts: Polyethylene Glycol Solvents: Ethanol; 1 H,65 °C; 3.5 H,65 °C
  标题:Study On The Synthesis Of O-Ethoxyphenol
  作者:Zhang,Liqiong; Chai,Duoli
  参考文献:Guangdong Huagong 日期:2009 卷标:36(4) 页码:43-45]
  
  = 94-71-3
  反应条件:1.1 Reagents: Sodium Hydroxide Solvents: Water1.2 Reagents: Polyethylene Glycol
  标题:Etherification Of Phenols Catalyzed By Solid-Liquid Phase Transfer Catalyst Peg-400 Without Solvent
  作者:Cao,Yu-Qing; Pei,Ben-Gao
  参考文献:Synthetic Communications 日期:2000 卷标:30(10) 页码:1759-1766]
  
  = 94-71-3
  反应条件:1.1 Reagents: Sodium Carbonate,Sodium Hydroxide Catalysts: Tetramethylammonium Bromide Solvents: Toluene,Water; Cooled; Heated; 6 H,0.2 - 1.0 Mpa,100 - 120 °C; 120 °C -> Rt1.2 Reagents: Hydrochloric Acid Solvents: Water; Ph 5 - 6,Rt
  标题:Preparation Of O-Ethoxyphenol From Catechol And Chloroethane
  参考文献:China

海关参考信息

• 2907210001-间苯二酚
  2908199090-其他酚的卤化衍生物
  2908999090-其他酚的硝化衍生物
  2918290000-其他含酚基羧酸
• 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
• 详情请参考：📖 海关编码查询和海关进出口税则

专利信息

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• ➥ 象形图和危险代码
• ➥ 防范代码详解
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