CAS: 109-68-2; Sym-Methylethylethylene

上下游产品

1,4-dioxane pyridine chlorosulfurous acid-(1-methyl-butyl ester) 3-ethyl-4-methyl-oxetan-2-one2,3,5,6-tetramethylpyridine 2-Pentyl acetate m-tolyl ether(1-methyl-butyl)-m-tolyl ether o-tolyl ether(1-methyl-butyl)-o-tolyl ether

间戊二烯置于(Pph)2Pd5 氢气体系中,用 N,N-二甲基甲酰胺 用作溶剂,20.0 °C,101.32 Kpa 条件下,反应生成2-戊烯
参考文献:钯配合物在加氢反应中作为催化剂形成的机理:I.配合物与分子氢的反应
标题:钯配合物在加氢反应中作为催化剂形成的机理:I.配合物与分子氢的反应
摘要:Ph 3 Ppd(oac)2 2与分子h 2的相互作用产生了零价钯(ph 3 P)2 Pd 2的双核络合物.该络合物与ch 2 Cl 2中的h 2可逆地相互作用,产生(ph 3 P)2 Pd 2 H 2.在氩气氛中(ph 3 P)2 Pd 2与[ph 3 Ppd(oac)2 2反应形成pd I的双核络合物带有金属-金属键.这些数据以及[ph 3 Ppd(oac)2 2和h 2之间反应的动力学研究结果)与该过程的自动催化机制相一致,包括催化pd Ii配合物还原的过程.Pd 0化合物.已经确定,比例为p /pd⩾1的合成的pd Ii,Pd I和pd 0的化合物在不饱和化合物的氢化中没有活性.当乙酸钯与(ph 3 P)2反应时,形成催化活性络合物(pph)2 Pd 5概率pd 2在h存在2.当将(ph 3 P)2 Pd 2的溶液用h 2和o 2(或在h 2的气氛中的h 2 O 2)的混合物处理时,会形成相同的化合物.(pph)2
Doi:10.1016/s0022-328X(00)85857-X

专利信息

专利号:US-11866398-B2
优先权日:2018-05-15
标 题:Total synthesis of prostaglandin J natural products by stereoretentive metathesis
发明人：LI JIAMING; CHEN XU; AHMED TONIA S; STOLTZ BRIAN M; GRUBBS ROBERT H
权利人:CALIFORNIA INST OF TECHN
摘要:This invention relates generally to the synthesis of Δ12-Prostaglandin J product using stereoretentive ruthenium olefin metathesis catalysts supported by dithiolate ligands. Δ12-Prostaglandin J products were generated with excellent selectivity (>99% Z) and in moderate to high/good yields (47% to 80% yield; 58% to 80% yield).

专利号:WO-2012017400-A1
优先权日:2010-08-03
标 题 :Synthesis of acyl-pantetheine derivatives and the use thereof in the synthesis of acyl-coenzyme a derivatives
发明人：VAN DIJK ALBERDINA AIKE; BADENHORST CHRISTOFFEL PETRUS STEPHANUS
权利人:UNIV NORTHWEST; VAN DIJK ALBERDINA AIKE; BADENHORST CHRISTOFFEL PETRUS STEPHANUS
摘要:The present invention relates to a novel synthesis method for acyl-pantetheine derivatives. The present invention further relates to the use of said synthesized acyl-pantetheine derivatives as a starting material in the enzymatic synthesis of acyl-coenzyme A derivatives. According to a first aspect thereof, the present invention provides a method for the synthesis of acyl-pantetheine derivatives, the method including the steps of: a) providing a source of pantetheine; b) providing a source of acyl ester; and c) contacting the source of pantetheine with the source of acyl ester to form the corresponding acyl-pantetheine derivative, having the general formula (I), wherein R is an acyl group.The present invention also provides a method for the synthesis of acyl-coenzyme A derivatives as well as the use of a source of pantetheine and a source of acyl ester in the preparation steps of these two methods.

专利号:US-7247752-B2
优先权日:2004-10-01
标 题 :Methods for the synthesis of astaxanthin
发明人：LOCKWOOD SAMUEL F; TANG PENG CHO; NADOLSKI GEOFF; JACKSON HENRY L; FANG ZHIQIANG; DU YISHU; YANG MIN; GEISS WILLIAM; WILLIAMS RICHARD; BURDICK DAVID
权利人:CARDAX PHARMACEUTICALS INC
摘要:A method used for synthesizing intermediates for use in the synthesis of carotenoids and carotenoid analogs, and/or carotenoid derivatives. In some embodiments, the invention includes methods for synthesizing optically active intermediates useful for the synthesis of optically active carotenoids. Synthesis of optically active carotenoids, in one embodiment, may be accomplished by forming an optically active dihydroxy intermediate from ketoisopherone. The optically active dihydroxy intermediate may be converted into optically active astaxanthin derivatives.

专利号:US-2004242897-A1
优先权日:2002-07-31
标题 :Universal support media for synthesis of oligomeric compounds
发明人：GUZAEV ANDREI P; MANOHARAN MUTHIAH
摘要:Compounds for the synthesis of oligomeric compounds, particularly oligonucleotides and oligonucleotide mimetics, are provided. In addition, methods for functionalizing a support medium with a first monomeric subunit and methods for the synthesis of oligomeric compounds utilizing the novel compounds bound to support media are provided.

专利号:US-2024228455-A1
优先权日:2021-04-27
标 题 :Synthesis of cbn and cbnv
发明人：KAVARANA MALCOLM J
权利人:TEEWINOT LIFE SCIENCES CORP
摘要:The invention includes chemical synthesis for preparing cannabinol (CBN) and cannabinovarin (CBNV). The process is suitable for inter alia the large-scale synthesis of pharmaceutical grade CBN and CBNV.

专利号:US-10751419-B2
优先权日:2014-05-01
标题:Method for synthesis of reactive conjugate clusters
发明人：MIGAWA MICHAEL T; YU JINGHUA; WAN W BRAD; PATEL SAYTEN P; VASQUEZ GUILLERMO; KINBERGER GARTH A; PRAKASH THAZHA P; SETH PUNIT P; SWAYZE ERIC E
权利人:IONIS PHARMACEUTICALS INC
摘要:Provided herein are improved methods for the synthesis of reactive conjugate clusters and intermediates used in such methods. In particular, improvements are provided that enhance the synthesis of reactive conjugate clusters by reducing the number of synthetic steps required. The reactive conjugate clusters prepared using the improved methods don't include any transacylation impurities that are formed using existing methods. The improved methods also provide an increase in overall yield and a cost benefit over existing methods.