CAS: 29921-57-1; Propan-2-Yl 2-Bromoacetate

上下游产品

bromoacetic acid isopropyl alcohol 1,2-dibromo-1-fluoro-ethene sodium isopropylate3-cyano-3,4-diphenyl-butyric acid β-cyano-β,β-diphenylpropionic acid β-Cyan-β-phenyl-propionsaeure-isopropylester β-Cyan-β-phenyl-glutarsaeure-diisopropylester

1-O-Ethyl 5-O-Methyl 2-(2-Bromoacetyl)-2-Butylpentanedioate 反应生成溴乙酸异丙酯
参考文献:Zalinyan M. G.; Arutyunyan V. S.; Dangyan M. T.,Ajkakan Ximiakan Amsagir,Arm. Xim. Zh.,1978,31,Ho 6,412-415,
标题:Zalinyan M. G.; Arutyunyan V. S.; Dangyan M. T.,Ajkakan Ximiakan Amsagir,Arm. Xim. Zh.,1978,31,Ho 6,412-415,

专利信息

专利号:US-9469614-B2
优先权日:2011-10-27
标 题:Synthesis of triazolopyrimidine compounds
发明人：ZUPANCIC BORUT; MARAS NENAD; STERK DAMJAN
权利人:LEK PHARMACEUTICALS
摘要:The present invention relates to the field of organic synthesis and describes the synthesis of specific triazolopyrimidine compounds and intermediates thereof as well as related derivatives.

专利号:EP-2586773-A1
优先权日:2011-10-27
标题 :Synthesis of Triazolopyrimidine Compounds
权利人:LEK PHARMACEUTICALS
摘要:The present invention relates to the field of organic synthesis and describes the synthesis of specific triazolopyrimidine compounds and intermediates thereof as well as related derivatives.

专利号:WO-2013113319-A1
优先权日:2012-01-31
标题 :Process for the preparation of strontium ranelate, intermediate or hydrates thereof
发明人：KOFTIS THEOCHARIS V; ROHIT RAVIKANT SONI; BHARAT BECHARBHAI BODA; DIPAKKUMAR NARSIBHAI BHUT; VIMALKUMAR SUBHIRBHAI PATEL
权利人:PHARMATHEN SA; KOFTIS THEOCHARIS V; ROHIT RAVIKANT SONI; BHARAT BECHARBHAI BODA; DIPAKKUMAR NARSIBHAI BHUT; VIMALKUMAR SUBHIRBHAI PATEL
摘要:The present invention relates to an improved process for the synthesis of strontium ranelate compound of formula I or its hydrates thereof. More particularly, the present invention relates to an economically viable and industrially feasible process for the preparation of strontium ranelate, intermediate or its hydrates thereof.

专利号:WO-2025096445-A1
优先权日:2023-10-30
标题:Synthesis of intermediates for the preparation of macrocyclic compounds
发明人：CHOI YOUNGGI; HUYNH HOAN
权利人:ALKERMES INC
摘要:Provided are methods for synthesizing intermediates useful in the preparation of compounds having activity against orexin-2 receptor.

专利号:WO-2016075082-A1
优先权日:2014-11-10
标题:Stereoselective reductive amination of alpha-chiral aldehydes using omega-transaminases for the synthesis of precursors of pregabalin and brivaracetam
发明人：ZEPECK FERDINAND; NERDINGER SVEN; KROUTIL WOLFGANG; FUCHS CHRISTINE; SIMON ROBERT
权利人:SANDOZ AG
摘要:The present invention relates to processes comprising a combined racemization and stereoselective reductive amination step in which an aldehyde compound of formula (I) is contacted with an (R)-selective ω-transaminase or an (S)-selective ω-transaminase to racemize the compound of formula (I) and obtain an amine compound of formula (II). These processes are useful for the preparation of precursors of pharmaceutically active agents such as brivaracetam and pregabalin.

专利号:US-4734495-A
优先权日:1985-07-17
标 题 :Process and intermediates for beta-lactam antibiotics
发明人：EVANS DAVID A; SJOGREN ERIC B
权利人:HARVARD COLLEGE
摘要:1-Benzyl(or substituted benzyl)-3β-[4(S)-aryloxazolidin-2-one-3-yl]-4β-(2-arylvinyl)azetidin-2-ones are provided via cycloaddition of a 4(S)-aryloxazolidin-2-one-3-ylacetyl halide and an imine formed with a benzylamine and a 3-arylacrolein, e.g. cinnamaldehyde. The azetidinones are useful chiral intermediates in an asymmetric synthesis of 1-carba(1-dethia)-3-hydroxy-3-cephem-4-carboxylic acids and esters and to monocyclic β-lactam antibiotics.