CAS: 37577-28-9; (1S,2R)-(+)-Norephedrine

上下游产品

CAS号79-24-3 硝基乙烷 | CAS号100-52-7 苯甲醛 | CAS号28549-12-4 S-(-)-苯乙醇腈 | CAS号14838-15-4 去甲基麻黄素 | CAS号25438-37-3 α-(三甲基甲硅烷氧基)苯基乙腈 | CAS号90-63-1 1-羟基-1-苯乙酮 | CAS号917-64-6 甲基碘化镁 | CAS号77943-39-6 (4R,5S)-(+)-4-甲... | CAS号58107-41-8 N-[(1R,2S)-2-hy... | CAS号125133-96-2 (4R,5R)-4-Methy... | CAS号187324-67-0 丙酸(1S,2R)-2-[N-... | CAS号77877-20-4 (4R,5S)-3-丙酰基-4... | CAS号187324-64-7 (1S,2R)-2-[N-苄基... | CAS号114389-70-7 (1S,2R)-2-二丁氨基-...

羟基(苯基)乙腈置于咪唑,4-二甲氨基吡啶,Sodium Tetrahydroborate体系中,用 乙醚 用作溶剂,化学反应 2.0H,反应生成左旋去甲麻黄碱
参考文献:Applications Of Optically Active Aryl Cyanohydrins In The Synthesis Of α-Hydroxy Aldehydes,α-Hydroxy Ketones And β-Hydroxy Amines
标题:Applications Of Optically Active Aryl Cyanohydrins In The Synthesis Of α-Hydroxy Aldehydes,α-Hydroxy Ketones And β-Hydroxy Amines
摘要:从芳基醛中制备的高光学纯度氰基卤素可转化为 α-羟基醛,β-羟基酮和β-羟基胺,且无任何外消旋化现象,在新引入的立体中心处,赤式二对映异构体通常具有非常好的立体选择性(90%).
Doi:10.1071/ch9902045

专利信息

专利号:US-7247752-B2
优先权日:2004-10-01
标 题 :Methods for the synthesis of astaxanthin
发明人：LOCKWOOD SAMUEL F; TANG PENG CHO; NADOLSKI GEOFF; JACKSON HENRY L; FANG ZHIQIANG; DU YISHU; YANG MIN; GEISS WILLIAM; WILLIAMS RICHARD; BURDICK DAVID
权利人:CARDAX PHARMACEUTICALS INC
摘要:A method used for synthesizing intermediates for use in the synthesis of carotenoids and carotenoid analogs, and/or carotenoid derivatives. In some embodiments, the invention includes methods for synthesizing optically active intermediates useful for the synthesis of optically active carotenoids. Synthesis of optically active carotenoids, in one embodiment, may be accomplished by forming an optically active dihydroxy intermediate from ketoisopherone. The optically active dihydroxy intermediate may be converted into optically active astaxanthin derivatives.

专利号:WO-0140193-A1
优先权日:1999-12-03
标题:Method for the synthesis of pyrazolines
发明人：BOLDI ARMEN M
权利人:CHEMRX ADVANCED TECHNOLOGIES I; BOLDI ARMEN M
摘要:The present invention provides a method for the synthesis of compounds of Formula (I). Also claimed are novel intermediates and their methods of synthesis.

专利号:US-2003162992-A1
优先权日:2001-12-14
标 题 :Preparation of intermediates useful in the synthesis of antiviral nucleosides
发明人：WATANABE KYOICHI A; DU JINFA
摘要:The present invention is an efficient process for the manufacture of α-acyloxyacetaldehyde, a key intermediate in the synthesis of 1,3-oxathiolane and 1,3-dioxolane nucleosides.

专利号:US-2002103381-A1
优先权日:2000-11-30
标 题 :Method for the synthesis of pyrazolines
发明人：BOLDI ARMEN M
摘要:The present invention provides a method for the synthesis of compounds of Formula I: n n n Also claimed are novel intermediates and their methods of synthesis.

专利号:US-8907104-B2
优先权日:2006-10-11
标 题 :Synthesis of enone intermediate
发明人：MYERS ANDREW G; BRUBAKER JASON D
权利人:HARVARD COLLEGE
摘要:The tetracycline class of antibiotics has played a major role in the treatment of infectious diseases for the past 50 years. However, the increased use of the tetracyclines in human and veterinary medicine has led to resistance among many organisms previously susceptible to tetracycline antibiotics. The recent development of a modular synthesis of tetracycline analogs through a chiral enone intermediate has allowed for the efficient synthesis of novel tetracycline analogs never prepared before. The present invention provides a more efficient route for preparing the enone intermediate.

专利号:US-5698741-A
优先权日:1995-05-25
标题 :Asymmetric synthesis of (-)6-chloro-4-cyclopropyl-ethynyl-4-trifluoromethyl-1,4-dihydro-2H-3,1-benzoxazin-2-one
发明人：THOMPSON ANDREW S; CORLEY EDWARD G; GRABOWSKI EDWARD J J; YASUDA NOBUYOSHI
权利人:MERCK & CO INC
摘要:An improved synthesis of a highly potent HIV reverse transcription inhibitor is disclosed, involving an acetylide and a trifluoromethyl ketone which produces a chiral product in the presence of a chiral amino alcohol.