专利号:US-6264962-B1 优先权日:1997-12-19 标 题:Use of cinnamic acid or of at least one of its derivatives in a cosmetic composition 发明人:BRETON LIONEL; GIRERD FLORENCE; RENAULT BEATRICE 权利人:OREAL 摘要:The invention relates to the use of cinnamic acid, or of at least one of its derivatives, in a cosmetic composition as an agent for promoting the synthesis of the skin's total lipids. n The invention also relates to a cosmetic composition comprising an effective amount of cinnamic acid or of at least one of its derivatives.
专利号:EP-1331924-B1 优先权日:2000-10-26 标题 :Use of beta-carotene and lycopene for treating ageing symptoms via the inhibition of the expression of the metalloproteinase of type 1 of the extracellular matrix 发明人:BRETON LIONEL; BAUR MARKUS 权利人:OREAL; NESTEC SA 摘要:Intimate admixtures of at least one carotenoid having provitamin A activity and at least one carotenoid devoid of provitamin A activity are well suited for treating the undesirable cutaneous signs of skin aging, in particular the determination of the skin and/or of the mucous membranes by inhibiting the activity and/or the expression of collagenases and by increasing the synthesis of collagen.
专利号:US-6660283-B2 优先权日:1997-12-19 标 题 :Use of cinnamic acid, or of at least one of its derivatives in a cosmetic composition 发明人:BRETON LIONEL; GIRERD FLORENCE; RENAULT BEATRICE 权利人:OREAL 摘要:The invention relates to the use of cinnamic acid, or of at least one of its derivatives, in a cosmetic composition as an agent for promoting the synthesis of the skin's total lipids.The invention also relates to a cosmetic composition comprising an effective amount of cinnamic acid or of at least one of its derivatives.
专利号:US-5855897-A 优先权日:1996-09-13 标题 :Topical composition and method for enhancing lipid barrier synthesis 发明人:PELLE EDWARD 权利人:E L MANAGEMENT CORP 摘要:The present invention relates to topical compositions useful in enhancing lipid synthesis in skin comprising an effective amount of cafestol, in combination with a pharmaceutically or cosmetically acceptable carrier. Such compositions are useful in treatment or prevention of dry skin and conditions in which the skin's lipid barrier is defective or damaged.
专利号:US-6716437-B1 优先权日:1993-09-13 标 题:Topical composition and method for enhancing lipid barrier synthesis 发明人:PELLE EDWARD; ANDERSON JON 权利人:E L MANAGEMENT CORP 摘要:The present invention relates to topical compositions useful in enhancing lipid synthesis in skin comprising an effective amount of cafestol or kahweol, or derivative thereof, in combination with a pharmaceutically or cosmetically acceptable carrier. Such compositions are useful in treatment or prevention of dry skin and conditions in which the skin's lipid barrier is defective or damaged.
专利号:US-6106846-A 优先权日:1995-09-19 标题 :Use of at least one thermal spring water from Vichy as a substance P antagonist 发明人:BRETON LIONEL; LECLAIRE JACQUES; DE LACHARRIERE OLIVIER 权利人:SOCIETEL OREAL S A 摘要:The present invention relates to the use of at least one thermal spring water from the Vichy basin as substance P antagonist in a cosmetic composition or for the preparation of a pharmaceutical composition. The invention also relates to the use of at least one thermal spring water from the Vichy basin in a cosmetic composition or for the preparation of a pharmaceutical composition, more especially a dermatological composition, intended for treating disorders associated with excessive synthesis and/or release of substance P.
1: Goldust M, Rezaee E, Raghiafar R. Topical ivermectin versus crotamiton cream 10% for the treatment of scabies. Int J Dermatol. 2014 Jul;53(7):904-8. doi: 10.1111/ijd.12447. Epub 2014 Jun 5. doi: 10.1684/ejd.2014.2288. doi: 10.3109/15569527.2013.768258. Epub 2013 Feb 25. doi: 10.1016/j.chemosphere.2012.04.018. Epub 2012 May 10. doi: 10.1111/j.1600-0625.2011.01433.x. doi: 10.2166/wst.2010.100. 9: Larson P. Review: topical permethrin was more effective than topical crotamiton or lindane for scabies. Evid Based Nurs. 2008 Apr;11(2):47. doi: 10.1136/ebn.11.2.47.
合成参考文献
参考文献:10.1001/archderm.140.5.563 摘要:Walton SF, McKinnon M, Pizzutto S, Dougall A, Williams E, Currie BJ. Acaricidal activity of Melaleuca alternifolia (tea tree) oil: in vitro sensitivity of sarcoptes scabiei var hominis to terpinen-4-ol. Arch Dermatol. 2004 May;140(5):563–6. doi: 10.1001/archderm.140.5.563. 参考文献:10.1542/pir.22-9-322|10.1542/pir.22.9.322 摘要:Morgan-Glenn PD. Scabies. Pediatr Rev. 2001 Sep;22(9):322–3. doi: 10.1542/pir.22-9-322. 参考文献:10.1136/ebn.11.2.47 摘要:Larson P. Review: topical permethrin was more effective than topical crotamiton or lindane for scabies. Evid Based Nurs. 2008 Apr;11(2):47. doi: 10.1136/ebn.11.2.47. 参考文献:10.1155/2011/169432 摘要:Oiso N, Kawada A. Review of allergic and photoallergic contact dermatitis from an ingredient in a medicament vehicle consisting of a compress, poultice, plaster, and tape. J Allergy (Cairo). 2011;2011():169432.