CAS: 60758-86-3; 3-Ethoxy-4-Methoxybenzonitrile

上下游产品

CAS号1131-52-8 3-乙氧基-4-甲氧基苯甲醛 | CAS号247569-89-7 3-乙氧基-4-甲氧基苯甲酰胺 | CAS号247570-05-4 3-benzyloxy-4-m... | CAS号621-59-0 异香兰素； 3-羟基-4-甲氧... | CAS号52805-46-6 3-羟基-4-甲氧基苯腈 | CAS号608141-41-9 阿普斯特 | CAS号108439-67-4 (3-乙氧基-4-甲氧基苯基)甲胺 | CAS号608141-42-0 (S)-1-(3-乙氧基-4-... | CAS号608142-27-4 阿普斯特中间体

Methyl 3-(Benzyloxy)-4-Methoxybenzoate置于三氯氧磷体系中,用 吡啶,N-甲基乙酰胺,二氯甲烷 作为反应溶剂,化学反应生成 3-乙氧基-4-甲氧基苯腈
参考文献:Anthranilic Acid Derivatives As Inhibitors Of The Cgmp-Phosphodiesterase
标题:Anthranilic Acid Derivatives As Inhibitors Of The Cgmp-Phosphodiesterase
摘要:式(I)的化合物 其中r1为氢;r2为硝基,氰基或卤素(较低)烷基;r3为苯基,其上取代一个或多个卤素,氰基和较低烷氧基的取代基;a为较低烷基烯基;r4为一个基团cr6R7R8,其中r6和r7与它们连接的碳原子一起形成一个环烷基,可选择地取代羟基,较低烷氧基或较低烷酰氨基;而r8为氢;其前药和盐.

专利信息

专利号:US-8242310-B2
优先权日:2008-09-10
标题:Processes for the preparation of aminosulfone compounds
发明人：SAINDANE MANOHAR T; GE CHUANSHENG
权利人:SAINDANE MANOHAR T; GE CHUANSHENG; CELGENE CORP
摘要:Processes for synthesizing aminosulfone compounds are provided. Aminosulfone compounds obtained using methods provided herein are useful in production or synthesis of isoindoline based PDE 4 modulators.

专利号:US-9688623-B2
优先权日:2012-02-21
标题:Processes for the preparation of (S)-1-(3-ethoxy-4-methoxyphenyl)-2-methanesulfonylethylamine
发明人：VENKATESWARALU JASTI; RAJENDIRAN CHINNAPILLAI; REDDY NALLAMADDI RAVIKUMAR; CONNOLLY TERRENCE JOSEPH; RUCHELMAN ALEXANDER L; ECKERT JEFFREY; FRANK ANTHONY JOSEPH
权利人:CELGENE CORP
摘要:Provided herein are new processes for the preparation of aminosulfone intermediates for the synthesis of 2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione, which is useful for preventing or treating diseases or conditions related to an abnormally high level or activity of TNF-α. Further provided herein are processes for the commercial production of (S)-1-(3-ethoxy-4-methoxyphenyl)-2-methanesulfonylethylamine.

专利号:US-9126906-B2
优先权日:2012-02-21
标 题:Asymmetric synthetic processes for the preparation of aminosulfone compounds
发明人：CONNOLLY TERRENCE J; RUCHELMAN ALEXANDER L; LEONG WILLIAM W
权利人:CELGENE CORP
摘要:Processes for synthesizing aminosulfone compounds are provided. The processes provided herein utilize asymmetric reduction reactions, e.g., asymmetric hydrogenation, of protected or unprotected enamine or ketone substrates. Aminosulfone compounds obtained using methods provided herein are useful in production or synthesis of sulfone group containing isoindoline based compounds.

专利号:CN-107011209-A
优先权日:2017-05-11
标 题:A new process for the synthesis of 3-methoxy-4-ethoxybenzonitrile

专利号:CN-104744323-A
优先权日:2015-03-11
标题 :Synthesis process of apremilast chiral amine intermediate

专利号:CN-108084078-B
优先权日:2016-11-24
标题 :Synthesis method of medicine apremilast for treating psoriatic arthritis diseases