专利号:US-2006025327-A1 优先权日:2004-07-30 标 题 :Hybrid molecules QA, wherein Q is an aminoquinoline and a is an antibiotic or a resistance enzyme inhibitor, their synthesis and their uses as antibacterial agent 发明人:SANCHEZ MURIEL; MEUNIER BERNARD 权利人:PALUMED S A & CT NAT DE LA REC 摘要:Aminoquinoline-antibiotic hybrid compounds in the form of hybrid molecules QA, wherein Q is an aminoquinoline and A is an antibiotic or a resistance enzyme inhibitor, their synthesis and their uses as antibacterial agent. This compound is defined by the general formula (I): n nQ-(Y 1 ) p —(U) p′ —(Y 2 ) p″ -A  (I) nin which n Q represents an aminoquinoline, (Y 1 ) p —(U) p′ —(Y 2 ) p″ — is an optional spacer arm and A is an antibiotic, one of its derivatives or precursors, or a resistance enzyme inhibitor. The invention unexpectedly enables the activity of the antibiotic to be improved.
专利号:WO-2009056955-A1 优先权日:2007-10-30 标题 :Amine-bearing phospholipids (abps), their synthesis and use 发明人:ZUMBUEHL ANDREAS 权利人:UNIV BASEL; ZUMBUEHL ANDREAS 摘要:Disclosed herein are amine-bearing phospholipids (ABP). The ABPs display many properties and functionalities of naturally occurring phospholipids, but also new properties and functionalities, such as the ability to polymerize while maintaining structural integrity, that may supplement or expand the functionalities of naturally occurring phospholipids.
专利号:US-2007060558-A1 优先权日:2004-07-30 标 题 :Hybrid molecules QA where Q is an aminoquinoline and A is an antibiotic residue, the synthesis and uses thereof as antibacterial agents 发明人:SANCHEZ MURIEL; MEUNIER BERNARD 权利人:CENTRE NAT RECH SCIENT 摘要:The invention concerns an aminoquinoline-antibiotic hybrid compound of general formula (I): Q—(Y 1 ) p —(U) p —(Y 2 ) p -A: wherein Q represents an aminoquinoline, (Y 1 ) p (U) p —(Y 2 ) p″ is an optional spacer and A is an antibiotic residue. The invention enables the antibiotic residue activity to be unexpectedly enhanced.
专利号:US-4704456-A 优先权日:1985-11-22 标 题 :Process for sultamicillin intermediate 发明人:ADAMS RICHARD C 权利人:PFIZER 摘要:An improved process for the preparation of the chloromethyl ester of sulbactam (chloromethyl penicillanate 1,1-dioxide), an intermediate in the synthesis of sultamicillin (the mixed methanediol ester of sulbactam and ampicillin).
专利号:RU-2064931-C1 优先权日:1993-06-18 标题:Method of synthesis of penicillanic acid 1,1-dioxide and its salt
专利号:CN-114016058-A 优先权日:2021-12-07 标 题 :A kind of method of electrochemical synthesis of alkyl sulfone compound