CAS: 105751-18-6; (S)-6-((((9H-Fluoren-9-yl)Methoxy)Carbonyl)Amino)-2-(((Benzyloxy)Carbonyl)Amino)Hexanoic Acid

相似化合物

10009-20-8 105047-45-8 106719-44-2

上下游产品

2-[(benzyloxy)carbonyl]-L-lysineN2-[(benzyloxy)carbonyl]-L-lysine (9-fluorenyl)methyl pentafluorophenyl carbonate (fluorenylmethoxy)carbonyl chloride N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide(S)-2-Benzyloxycarbonylamino-6-(9H-fluoren-9-ylmethoxycarbonylamino)-hexanoic acid 2-trimethylsilanyl-ethyl ester Fm°C-Z-Lys-Pfp α-carbobenzyloxy-Nε-9-fluorenylmethoxycarbonyl-L-lysylglycin tert-butyl esterNα-carbobenzyloxy-Nε-9-fluorenylmethoxycarbonyl-L-lysylglycin tert-butyl ester (α)-benzyloxycarbonyl-N(ε)-9-fluorenylmethyloxycarbonyl-L-lysine benzyl esterN(α)-benzyloxycarbonyl-N(ε)-9-fluorenylmethyloxycarbonyl-L-lysine benzyl ester

N-Alpha-Cbz-L-赖氨酸,9-芴甲基-N-琥珀酰亚胺基碳酸酯置于sodium Carbonate Decahydrate体系中,用 1,4-二氧六环,水 用作溶剂,以100%的收率获得n-ε-芴甲氧羰基-N-Alpha-苄氧羰基-L-赖氨酸
参考文献:Synthesis And Structural Characterization Of The Individual Diastereoisomers Of A Cross-Stapled Alkene-Bridged Nisin De-Ring Mimic
标题:Synthesis And Structural Characterization Of The Individual Diastereoisomers Of A Cross-Stapled Alkene-Bridged Nisin De-Ring Mimic
摘要:在本文中,我们介绍了一种交叉叠层烯桥六肽的合成,结构表征和作为高级中间体的合成用途,这种六肽可以模拟兰替比星的 De 环.线性前体通过闭环偏析环化,一步就得到了折叠正确的双环六肽,并分离出四种非对映异构体,分别通过 HPLC,NMR 和 Ms 对其进行结构鉴定和表征.该双环六肽被用作一种多功能高级合成物,并在其 C 端和 N 端用叠氮基等进行了修饰,从而获得了一种适合 Cu(I)-催化的炔吖啶环化连接反应的构筑基块.
Doi:10.1039/c3Ob41359D