CAS: 120-18-3; Naphthalene-2-Sulfonic Acid

上下游产品

CAS号91-20-3 萘 | CAS号91-60-1 2-巯基萘 | CAS号93-11-8 2-萘磺酰氯 | CAS号5586-15-2 2-萘二硫醚 | CAS号532-02-5 2-萘磺酸钠 | CAS号613-49-0 2-萘磺酸 | CAS号63296-70-8 N,N-dimethylnap... | CAS号5138-53-4 methyl naphthal... | CAS号81-06-1 1-氨基萘-2-磺酸 | CAS号92-41-1 2,7-二磺酸萘 | CAS号581-75-9 2,6-萘二磺酸 | CAS号5724-16-3 naphthalene-1,7... | CAS号525-37-1 1,6-萘二磺酸 | CAS号6094-26-4 1,3-Naphthalene... | CAS号86-66-8 萘-1,3,6-三磺酸 | CAS号513-81-5 2,3-二甲基-1,3-丁二烯 | CAS号493-01-6 萘烷 | CAS号493-02-7 反-十氢化萘 | CAS号935-31-9 Cyclodecene, (1Z)

萘置于1,3-Disulfonic Acid Imidazolium Chloride体系中,用 水 用作溶剂,化学反应 0.22H,以72%的收率获得2-萘磺酸
参考文献:1,3-二磺酸咪唑氯化物在水性介质中区域选择性磺化芳香族化合物
标题:1,3-二磺酸咪唑氯化物在水性介质中区域选择性磺化芳香族化合物
摘要:1,3-二磺酸咪唑氯化物 ([dsim]Cl) 作为一种布朗斯台德酸性离子液体,通过在温和条件和水性介质中在 50 oc 下原位生成硫酸,用于芳族化合物的磺化.
Doi:10.1055/s-0035-1561938

专利信息

专利号:US-2006287520-A1
优先权日:2005-05-16
标 题 :Synthesis of salinosporamide A and analogues thereof
发明人：DANISHEFSKY SAMUEL J; ENDO ATSUSHI
权利人:DANISHEFSKY SAMUEL J; ENDO ATSUSHI
摘要:A novel synthesis of salinosporamide A is provided. Salinospoamide A as well as structurally related natural products, omuralide and lactacystin, have been shown to be proteasome inhibitors. Therefore, these compounds as well as analogues of these natural products may be useful in the treatment of proliferative diseases such as cancer, autoimmune diseases, diabetic retinopathy, etc. The invention provides for the synthesis of salinosporamide A as well as analogs thereof using a convenient point for derivatization of the bicyclic core. Pharmaceutical compositions and method of using the inventive compounds are also provided.

专利号:US-9643915-B2
优先权日:2013-03-15
标题:Methods for the synthesis of sphingomyelins and dihydrosphingomyelins
发明人：ONICIU DANIELA CARMEN; HECKHOFF STEFAN; OSWALD BENOIT; REBMANN PETER; PEER ANDREAS; GONZALEZ MIGUEL; SAUTER PATRIK
权利人:CERENIS THERAPEUTICS HOLDING SA
摘要:The present invention includes methods for the synthesis of sphingomyelins and dihydrosphingomyelins. The present invention also includes methods for the synthesis of sphingosines and dihydrosphingosines. The present invention further includes methods for the synthesis of ceramides and dihydroceramides.

专利号:US-9708354-B2
优先权日:2013-03-15
标 题:Methods for the synthesis of sphingomyelins and dihydrosphingomyelins
发明人：ONICIU DANIELA CARMEN; HECKHOFF STEFAN; OSWALD BENOIT; REBMANN PETER; PEER ANDREAS; GONZALEZ MIGUEL; SAUTER PATRIK
权利人:CERENIS THERAPEUTICS HOLDING SA
摘要:The present invention includes methods for the synthesis of sphingomyelins and dihydrosphingomyelins. The present invention also includes methods for the synthesis of sphingosines and dihydrosphingosines. The present invention further includes methods for the synthesis of ceramides and dihydroceramides.

专利号:US-9376461-B2
优先权日:2011-06-06
标 题:Non-enzymatic synthesis of O-acetyl-ADP-ribose and analogues thereof
发明人：KOPPETSCH KARSTEN; SZCZEPANKIEWICZ BRUCE G; PERNI ROBERT B
权利人:KOPPETSCH KARSTEN; SZCZEPANKIEWICZ BRUCE G; PERNI ROBERT B; GLAXOSMITHKLINE LLC
摘要:Provided herein is a simple, one-step, non-enzymatic synthesis of O-Acetyl-ADP-ribose (OAADPR) from NAD and sodium acetate in acetic acid. The extension of this reaction to other carboxylic acids, demonstrates that the reaction between NAD, and NAD analogs produces mixtures of the corresponding 2′- and 3′-carboxylic esters. Included are O-carboxyl-ADP-ribose compounds and corresponding methods of synthesis (e.g., O-propionyl-ADP-ribose, O-succinyl-ADP-ribose, O-malonyl-ADP-ribose), as well as non-adenosine nucleoside compounds.

专利号:US-7910623-B2
优先权日:2005-07-22
标 题 :Synthesis of scabronines and analogues thereof
发明人：DANISHEFSKY SAMUEL J; WATERS STEPHEN P
权利人:SLOAN KETTERING INST CANCER
摘要:A novel synthesis of scabronines, which are related to a broader class of angularly fused tricyclic diterpenoids known as cyathanes, is provided. Scabronine G, its methyl ester derivative, and other analogs have been shown to have neurotrophic activity. Therefore, these compounds are particularly useful in treating neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, Huntington's diseases, etc. The invention provides for the synthesis of scabronines as well as analogs thereof. Pharmaceutical compositions and method of using the inventive compounds are also provided.

专利号:US-2013040990-A1
优先权日:2010-02-02
标题 :SYNTHESIS OF DGJNAc FROM D-GLUCURONOLACTONE AND USE TO INHIBIT ALPHA-N-ACETYLGALACTOSAMINIDASES
发明人：FLEET GEORGE WILLIAM JOHN; BUTTERS TERRY DOUGLAS
权利人:UNIV OXFORD; FLEET GEORGE WILLIAM JOHN; BUTTERS TERRY DOUGLAS
摘要:A convenient and scalable synthesis of DGJNAc ID from D-glucuronolactone in an overall yield of 20% is provided. DGJNAc is the first highly potent and specific competitive inhibitor of GalNAcases. DGJNAc ID is also a competitive inhibitor of -hexosaminidases. Synthesis and activity of L-DGJNAc IL is also shown. The use of DGJNAc as a potent and specific inhibitor of GalNAcases will allow useful investigation and treatment of a number of diseases, including Schindler Disease.