50-70-4 = 87-79-6 反应条件:1.1 Reagents: Nadp Catalysts: L-Iditol Dehydrogenase Solvents: Water; Ph 7 - 8,30 °C 标题:Overcoming Nadph Product Inhibition Improves D-Sorbitol Conversion To L-Sorbose 作者:Kim,Tae-Su; Hui,Gao; Li,Jinglin; Kalia,Vipin C.; Muthusamy,Karthikeyan; Et Al 参考文献:Scientific Reports 日期:2019 卷标:9(1) 页码:1-9]
50-81-7 = 87-79-6 [标题:Reaction Conditions 标题:Enhanced Production Of L-Sorbose From D-Sorbitol By Improving The Mrna Abundance Of Sorbitol Dehydrogenase In Gluconobacter Oxydans Wsh-003 作者:Xu,Sha; Wang,Xiaobei; Du,Guocheng; Zhou,Jingwen; Chen,Jian 参考文献:Microbial Cell Factories 日期:2014 卷标:13 页码:146/1-146/7]
50-70-4 = 87-79-6 反应条件:1.1 Solvents: Water 标题:Conversion Of L-Rhamnose Into Ten Of The Sixteen 1- And 6-Deoxyketohexoses In Water With Three Reagents: D-Tagatose-3-Epimerase Equilibrates C3 Epimers Of Deoxyketoses 作者:Gullapalli,Pushpakiran; Yoshihara,Akihide; Morimoto,Kenji; Rao,Devendar; Akimitsu,Kazuya; Et Al 参考文献:Tetrahedron Letters 日期:2010 卷标:51(6) 页码:895-898]
50-70-4 = 87-79-6 反应条件:1.1 Reagents: Oxygen Solvents: Water 标题:Productivity Improvement In L-Sorbose Biosynthesis By Fedbatch Cultivation Of Gluconobacter Oxydans 作者:Giridhar,Raghavan Nair; Srivastava,Ashok Kumar 参考文献:Journal Of Bioscience And Bioengineering 日期:2002 卷标:94(1) 页码:34-38]
50-70-4 = 87-79-6 反应条件:1.1 Catalysts: Triacylglycerol Lipase Solvents: Water 标题:Fed-Batch Cultivation Of Acetobacter Suboxydans For The Microbial Oxidation Of D-Sorbitol To L-Sorbose 作者:Giridhar,R.; Srivastava,A. K. 参考文献:Bioprocess Engineering 日期:2000 卷标:23(6) 页码:575-577]
220427-56-5 = 87-79-6 反应条件:1.1 Reagents: Hydrogen Catalysts: Palladium Solvents: Ethanol; 24 H,50 Psi,Rt 标题:Chemical Synthesis Of 1-Deoxy-L-Fructose And L-Sorbose Through Carbonyl Translocation 作者:Wu,Hsin-Pei; Hsu,Nai-Yun; Lu,Tai-Ni; Chang,Che-Chien 参考文献:European Journal Of Organic Chemistry 日期:2015 卷标:2015(2) 页码:378-382]
87-79-6 = 87-79-6 反应条件:1.1 Reagents: Sodium Solvents: Methanol1.2 Reagents: Lanthanum Chloride (Lacl3) Solvents: Methanol 标题:Synthesis And Characterisation Of Saccharide Complexes Of La(Iii) Ion 作者:Mukhopadhyay,Anindita; Kolehmainen,Erkki; Rao,Chebrolu Pulla 参考文献:Indian Journal Of Chemistry 日期:2002 卷标:(8) 页码:1621-1624]
6027-89-0 = 87-79-6 反应条件:1.1 Catalysts: Alumina Solvents: Pyridine; 30 Min,Reflux 标题:Aldose-Ketose Inter-Conversion In Pyridine In The Presence Of Aluminum Oxide 作者:Ekeberg,Dag; Morgenlie,Svein; Stenstrom,Yngve 参考文献:Carbohydrate Research 日期:2007 卷标:342(14) 页码:1992-1997]
50-70-4 = 87-79-6 反应条件:1.1 Reagents: Urea,Calcium Carbonate,Sodium Hydroxide,Sulfuric Acid Magnesium Salt (1:1),Monopotassium Phosphate,Oxygen Solvents: Water; 24 H,Ph 7.0,30 °C 标题:Reorganization Of A Synthetic Microbial Consortium For One-Step Vitamin C Fermentation 作者:Wang,En-Xu; Ding,Ming-Zhu; Ma,Qian; Dong,Xiu-Tao; Yuan,Ying-Jin 参考文献:Microbial Cell Factories 日期:2016 卷标:15 页码:21/1-21/11]
96-26-4 + 497-09-6 = 87-79-6 反应条件:1.1 Catalysts: Transaldolase,Fructose-6-Phosphate Aldolase Solvents: Water; 24 - 48 H,Ph 8.5,Rt 标题:Broadening Deoxysugar Glycodiversity: Natural And Engineered Transaldolases Unlock A Complementary Substrate Space 作者:Rale,Madhura; Schneider,Sarah; Sprenger,Georg A.; Samland,Anne K.; Fessner,Wolf-Dieter 参考文献:Chemistry - A European Journal 日期:2011 卷标:17(9) 页码:2623-2632]
50-70-4 = 87-79-6 反应条件:1.1 Solvents: Water 标题:Computer Coupled Substrate Feeding Strategies For Efficient Conversion Of D-Sorbitol To L-Sorbose In Fed-Batch Culture 作者:Giridhar,R.; Srivastava,Ashok K. 参考文献:Process Biochemistry (Oxford 日期:2001 卷标:36(8-9) 页码:829-834
蔗糖置于alternansucrase Asr C-Del Bis Sodium Acetate体系中,用 水 作为反应溶剂,化学反应生成 2-己酮醣 参考文献:Fully Active Alternansucrases Partially Deleted In Its Carboxy-Terminal And Amino-Terminal Domains And Mutants Thereof 标题:Fully Active Alternansucrases Partially Deleted In Its Carboxy-Terminal And Amino-Terminal Domains And Mutants Thereof 摘要:提供了截断或突变的交替糖基转移酶的核酸序列,包含这些核酸序列的载体,以及转化了编码截断或突变的交替糖基转移酶的核酸序列的宿主细胞.此外,还描述了一种重组交替糖基转移酶的过程,该过程具有高水平的表达,并保留酶活性.
专利号:US-7601318-B2 优先权日:2000-09-26 标 题:Method for synthesis of carbon-coated redox materials with controlled size 发明人:ARMAND MICHEL; GAUTHIER MICHEL; MAGNAN JEAN-FRANCOIS; RAVET NATHALIE 权利人:HYDRO QUEBEC; CENTRE NAT RECH SCIENT; UNIV MONTREAL 摘要:A method for the synthesis of compounds of the formula C—Li x M 1−y M′ y (XO 4 ) n , where C represents carbon cross-linked with the compound Li x M 1−y M′ y (XO 4 ) n , in which x, y and n are numbers such as 0≦x≦2, 0≦y≦0.6, and 1≦n≦1.5, M is a transition metal or a mixture of transition metals from the first period of the periodic table, M′ is an element with fixed valency selected among Mg 2+ , Ca 2+ , Al 3+ , Zn 2+ or a combination of these same elements and X is chosen among S, P and Si, by bringing into equilibrium, in the required proportions, the mixture of precursors, with a gaseous atmosphere, the synthesis taking place by reaction and bringing into equilibrium, in the required proportions, the mixture of the precursors, the procedure comprising at least one pyrolysis step of the carbon source compound in such a way as to obtain a compound in which the electronic conductivity measured on a sample of powder compressed at a pressure of 3750 Kg·cm −2 is greater than 10 −8 S·cm −1 . The materials obtained have excellent electrical conductivity, as well a very improved chemical activity.
专利号:US-9034844-B2 优先权日:2009-04-06 标 题 :6′-sialyllactose salts and process for their synthesis and for the synthesis of other alpha-sialyloligosaccharides 发明人:TAMERLANI GIANCARLO; LOMBARDI ILARIA; BARTALUCCI DEBORA; DANESI ANDREA; SALSINI LIANA; MANONI MARCO; CIPOLLETTI GIOVANNI 权利人:TAMERLANI GIANCARLO; LOMBARDI ILARIA; BARTALUCCI DEBORA; DANESI ANDREA; SALSINI LIANA; MANONI MARCO; CIPOLLETTI GIOVANNI; INALCO SPA 摘要:The present invention relates to a process of synthesis of α-sialyl oligosaccharides and in particular of 6′-sialyllactose and its salts comprising a step of coupling by Koenigs-Knorr reaction under conditions that allow its use on an industrial scale.
专利号:US-12146136-B2 优先权日:2020-03-26 标题:Synthesis of modified oligonucleotides with increased stability 发明人:KHVOROVA ANASTASIA; ROUX LOÃ?C MAURICE RENÉ JEAN; YAMADA KEN 权利人:UNIV MASSACHUSETTS 摘要:This disclosure relates to the synthesis of novel modified oligonucleotides. The synthesis of novel phosphoramidites are also provided.
专利号:EP-0349059-B1 优先权日:1988-06-29 标题:Process for the synthesis of polyol fatty acid polyesters 发明人:WILLEMSE GERARDUS W 权利人:UNILEVER NV; UNILEVER PLC 摘要:The application pertains to a process for the synthesis of polyol fatty acid polyesters, in which a polyol and/or a fatty acid oligoester thereof, is esterified by reaction with fatty acid lower alkylester under substantially solvent-free conditions at elevated temperature in the presence of a transesterification catalyst and, optionally an emulsifier, and in which at least during the final stage of the transesterification reaction the reaction mixture is submitted to the action of a stripping agent suitable for accelerating the removal of the lower alkyl alcohol formed in said reaction. The process is of particular advantage in the synthesis of polyesters of very high degrees of conversion.
专利号:US-2023183177-A1 优先权日:2020-04-24 标题:Enantioselective chemo-enzymatic synthesis of optically active amino amide compounds 发明人:GRILL BIRGIT; WINKLER MARGIT; SCHWAB HELMUT; STROHMEIER GERNOT; DONSBACH KAI; WALDVOGEL SIEGFRIED R; ARNDT SEBASTIAN; WEIS DOMINIK 权利人:PHARMAZELL GMBH 摘要:The present invention relates to a novel biocatalytic process for the stereoselective preparation of alpha amino amide compounds catalyzed by NHase enzymes. A further aspect of the invention relates to novel NHase enzymes as well as further improved NHase enzyme mutants, nucleic acid molecules encoding these enzymes, recombinant microorganisms suitable for preparing such enzymes and mutants. Another aspect of the invention relates to a chemo-biocatalytic process for the preparation of lactam compounds comprising the new catalytic process for the preparation of alpha amino amide compounds catalyzed by NHase enzymes, as well as the chemical oxidation of the alpha amino amide by applying certain chemical oxidation catalysts suitable for converting the alpha amino amide under retention of its stereochemical configuration to the respective lactam. The novel chemo-biocatalytic process is particularly suited for the synthesis of valuable pharmaceutical compounds, like in particular (S)-Levetiracetam.
专利号:US-5939304-A 优先权日:1997-06-05 标题:Method for synthesis of anhydrothrombin 发明人:SUZUKI TOYOAKI; HOSOKAWA KAZUYA; NAGATA MASANORI 权利人:FUJIMORI KOGYO CO 摘要:A method for a synthesis of anhydrothrombin is provided which features a short process, an easy procedure, and high yields. n The method comprises n (A) a step of causing an active serine residue site of thrombin to react with an inhibitor, n (B) a step of performing an alkali treatment at a pH of not less than 11, and n (C) a step of performing an operation of recovery, and carries out these steps sequentially in the order mentioned, and is characterized by causing at least the step of performing the operation of recovery to proceed in the presence of at least one compound selected from the group consisting of polyhydric alcohols and saccharides, and a salt or an amphoteric electrolyte.
1: Wang CY, Li Y, Gao ZW, Liu LC, Zhang MY, Zhang TY, Wu CF, Zhang YX. Establishing an innovative carbohydrate metabolic pathway for efficient production of 2-keto-L-gulonic acid in Ketogulonicigenium robustum initiated by intronic promoters. Microb Cell Fact. 2018 May 19;17(1):81. doi: 10.1186/s12934-018-0932-9. 2: He Y, Mao C, Chen Z, Wen H, Lu W, Wu H. Identification of differential metabolites in liquid diet fermented with Bacillus subtilis using gas chromatography time of flight mass spectrometry. Anim Nutr. 2016 Dec;2(4):351-356. doi: 10.1016/j.aninu.2016.07.007. Epub 2016 Jul 30. 3: Vergne-Vaxelaire C, Mariage A, Petit JL, Fossey-Jouenne A, Guérard-Hélaine C, Darii E, Debard A, Nepert S, Pellouin V, Lemaire M, Zaparucha A, Salanoubat M, de Berardinis V. Characterization of a thermotolerant ROK-type mannofructokinase from Streptococcus mitis: application to the synthesis of phosphorylated sugars. Appl Microbiol Biotechnol. 2018 May 4. doi: 10.1007/s00253-018-9018-1. [Epub ahead of print] doi: 10.1021/acs.biochem.8b00392. Epub 2018 Apr 30.
合成参考文献
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