CAS: 10397-13-4; 4-(4,6-Dichloropyrimidin-2-yl)Morpholine

相似化合物

24192-96-9 3549-05-1 1282537-80-7

上下游产品

1,1'-oxybis(2-bromo-ethane) 2-Amino-4,6-dichloropyrimidine morpholine 2,4,6-trichloropyrimidine N'-(6-chloro-2-morpholin-4-yl-pyrimidin-4-yl)benzene-1,2-diamine 4-(6-chloro-2-(2-(pyridin-2-yl)ethoxy)pyrimidin-4-yl)morpholine 6-[2-(pyridin-2-yl)-ethoxy]-2-chloro-4-(morpholin-4-yl)-pyrimidine 4-[2-(pyridin-2-yl)-ethoxy]-6-chloro-2-(morpholin-4-yl)-pyrimidine

2-吗啉嘧啶-4,6-二醇 以50的收率获得2-吗啉基-4,6-二氯嘧啶
参考文献:Dexamethasone Combination Therapy
标题:Dexamethasone Combination Therapy
摘要:本发明涉及一种治疗多发性骨髓瘤的方法,包括向患者施用(1)公式(i)所述的化合物及/或其立体异构体,互变异构体或其药学上可接受的盐的量,以及(2)地塞米松和/或其药学上可接受的盐,溶剂,代谢物或外消旋体的量,从而治疗患者.在另一个方面,本发明提供了一种治疗多发性骨髓瘤的方法,包括向患者施用(1)公式(i)的化合物的量和(2)地塞米松的量,从而治疗患者;用于治疗多发性骨髓瘤的上述组合物的药物制剂;以及它们的组成物.

专利信息

专利号:US-2023399302-A1
优先权日:2020-10-29
标题:Process for the preparation of heteroaryl-substituted sulfur(vi) compounds
发明人：LOPCHUK JUSTIN M; SHULTZ ZACHARY P; SCATTOLIN THOMAS
权利人:H LEE MOFFITT CANCER CT & RES
摘要:The present disclosure provides processes for the synthesis of organic compounds, in particular processes for the synthesis of heteroaryl-substituted sulfur(VI) compounds by nucleophilic aromatic substitution.

专利号:US-7923557-B2
优先权日:2004-11-10
标 题:Process for preparing trisubstituted pyrimidine compounds
发明人：ZHANG SHIJIE; KOSTIK ELENA; SUN LIJUN
权利人:SYNTA PHARMACEUTICALS CORP
摘要:Disclosed herein is a regioselective synthesis of compounds represented by formula (I): n nor a salt, solvate, clathrate, or prodrug thereof, wherein X, Y, R 2 , R 3 , R 4 , R 7 , R 8 , R 9 , R 10 , m and n are defined as within.