CAS: 66-84-2; (2R,3R,4S,5R)-2-Amino-3,4,5,6-Tetrahydroxyhexanal Hydrochloride

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CAS号9012-76-4 壳聚糖 | CAS号3006-60-8 2-(乙酰氨基)-2-脱氧-B... | CAS号3068-34-6 2-乙酰氨基-3,4,6-三-... | CAS号3416-24-8 氨基葡萄糖 | CAS号41107-82-8 2,5-脱水-D-甘露醇 | CAS号123-76-2 乙酰丙酸 | CAS号290-37-9 吡嗪 | CAS号109-08-0 2-甲基吡嗪 | CAS号98-00-0 糠醇 | CAS号67-47-0 5-羟甲基糠醛 | CAS号6705-31-3 2-(吡嗪-2-基)乙-1-醇 | CAS号55087-82-6 1-[5-(hydroxyme...

Alkaline Earth Salt Of/the/ Methylsulfuric Acid置于水体系中,化学反应生成 D-氨基葡萄糖盐酸盐
参考文献:Tanret,Bulletin De La Societe Chimique De France,1897,Vol. <3>17,P. 802
标题:Tanret,Bulletin De La Societe Chimique De France,1897,Vol. <3>17,P. 802

专利信息

专利号:US-2004058888-A1
优先权日:2000-01-13
标题:Methods for synthesis of alpha-d-gal (1~>3) gal-containing oligosaccharides
发明人：BORNAGHI LAURENT; DEKANY GYULA; DRINNAN NICHOLAS BARRY; PAPAGEORGIOU JOHN; WEST MICHAEL LEO
摘要:This invention relates to reagents and methods for synthesis of biologically active di- and tri-saccharides comprising α-D-Gal(1→3)-D-Gal. In particular the invention provides novel reagents, intermediates and processes for the solution or solid phase synthesis of α-D-galactopyranosyl-(1→3)-D-galactose, and derivatives thereof. In one preferred embodiments the invention provides a protected monosaccharide building block of general formula (II): in which R 3 is methoxy or methyl; R 1 is H, benzoyl, pivaloyl, 4-chlorobenzoyl, acetyl, chloroacetyl, levulinoyl, 4-methylbenzoyl, benzyl, 3,4-methylenedioxybenzyl, 4-methoxybenzyl, 4-chlorobenzyl, 4-acetamidobenzyl, or 4-azidobenzyl; and R 2 is H, Fmoc, benzoyl, pivaloyl, 4-chlorobenzoyl, acetyl, chloroacetyl, levulinoyl, 4-methylbenzoyl, benzyl, 3,4-methylenedioxybenzyl, 4-methoxybenzyl, 4 -chlorobenzyl, 4-acetamidobenzyl, or 4-azidobenzyl.

专利号:WO-2022107013-A1
优先权日:2020-11-19
标 题 :Silver assisted gold catalysis for the preparation of fondaparinux pentasaccharide and intermediates
发明人：HOTHA SRINIVAS; WALKE GULAB; KASDEKAR NITESHLAL; SUTAR YOGESH
权利人:INDIAN INSTITUTE OF SCIENCE EDUCATION AND RES
摘要:The present invention relates to a process for the synthesis of Fondaparinux pentasaccharide and its intermediates. Specifically, the present invention relates to a novel catalytic process for the synthesis of Fondaparinux pentasaccharide and its intermediates. The present invention further relates to a silver assisted gold catalysis for glycosylation reactions in the synthesis of Fondaparinux pentasaccharide and its intermediates. (I)

专利号:US-10925977-B2
优先权日:2006-10-05
标 题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications
发明人：YANG DAVID J; YU DONGFANG; THOMPSON ANDREW S
权利人:YANG DAVID J; YU DONGFANG; THOMPSON ANDREW S; CEIL POINT LLC; UNIV TEXAS
摘要:Novel methods of synthesis of chelator-targeting ligand conjugates, compositions comprising such conjugates, and therapeutic and diagnostic applications of such conjugates are disclosed. The compositions include chelator-targeting ligand conjugates optionally chelated to one or more metal ions. Methods of synthesizing these compositions in high purity are also presented. Also disclosed are methods of imaging, treating and diagnosing disease in a subject using these novel compositions, such as methods of imaging a tumor within a subject and methods of diagnosing myocardial ischemia.

专利号:WO-2023212134-A9
优先权日:2022-04-28
标题:Methods for synthesis of peracetylgalactosamine-1-pentanoic acid
发明人：VAGLE KURT; BHADURI SAYANTAN
权利人:DICERNA PHARMACEUTICALS INC
摘要:The disclosure provides methods for synthesis of peracetylgalactosamine-1-pentanoic acid, also called peracetylated D-galactosamine C5 linker or GalNAc C5 linker, using a vegetal source as a starting material, such as vegetal-sourced D-glucosamine or D-glucosamine hydrochloride.Also provided are methods for purifying the peracetylgalactosamine-1-pentanoic acid, or GalNAc C5 linker, thus produced so that the end product comprises fewer impurities.

专利号:US-5654412-A
优先权日:1996-05-29
标 题:Processes for the synthesis of sialyl Lewisx compounds
发明人：SRIVASTAVA OM; GREGSON JONATHAN M
权利人:GLYCOMED INC
摘要:Disclosed are processes for the chemical synthesis of sialyl Lewisx-Y compounds where Y is -OH, -NHR, -SH, -SR or -OR, and R is an aglycon of at least one carbon atom.

专利号:US-6846917-B2
优先权日:2001-01-23
标题:Solid- and solution-phase synthesis of heparin and other glycosaminoglycans
发明人：SEEBERGER PETER H; ORGUEIRA HERNAN; SCHELL PETER
权利人:MASSACHUSETTS INST TECHNOLOGY
摘要:Described is a modular, general synthetic strategy for the preparation in solution and on a solid support of heparin, heparin-like glycosaminoglycans, glycosaminoglycans and non-natural analogs of each of them. Additionally, the modular strategy provides the basis for the preparation of combinatorial libraries and parallel libraries of defined glycosaminoglycan oligosaccharides. The defined glycosaminoglycan structures may be used in high-throughput screening experiments to identify carbohydrate sequences that regulate a host of recognition and signal-transduction processes. The determination of specific sequences involved in receptor binding holds great promise for the development of molecular tools which will allow modulation of processes underlying viral entry, angiogenesis, kidney diseases and diseases of the central nervous system. Notably, the present invention enables the automated synthesis of glycosaminoglycans in much the same fashion that peptides and oligonucleotides are currently assembled.