CAS: 146548-59-6; 1-(2,4,6-Trimethoxyphenyl)Methanamine Hydrochloride

相似化合物

20781-21-9 34967-23-2 1255942-75-6

上下游产品

2,4,6-trimethoxybenzonitrile [(S)-5-((S)-2-Benzyloxycarbonylamino-4-methyl-pentanoylamino)-5-(2,4,6-trimethoxy-benzylcarbamoyl)-pentyl]-carbamic acid benzyl ester (S)-4-((S)-2-tert-Butoxycarbonylamino-4-methyl-pentanoylamino)-4-(2,4,6-trimethoxy-benzylcarbamoyl)-butyric acid benzyl ester Z-Glu(t-Bu)-Lys(B°C)-NHTmb (S)-2-Benzyloxycarbonylamino-4-(2,4,6-trimethoxy-benzylsulfamoyl)-butyric acid

2,4,6-三甲氧基苯甲腈置于potassium Tert-Butylate,Sodium Hydroxide,盐酸体系中,用 四氢呋喃,水,甲醇,乙醚 用作溶剂,化学反应 12.33H,以65%的收率获得2,4,6-三甲氧基苄胺盐酸盐
参考文献:酚基铁(III)配合物通过聚甲基氢硅氧烷催化还原腈
标题:酚基铁(III)配合物通过聚甲基氢硅氧烷催化还原腈
摘要:使用廉价的硅烷(如聚甲基氢硅氧烷(pmhs))将腈还原为伯胺是工业上重要的反应.在这里,我们报告了合成的带有稀土基配体的富地球的fe(III)配合物,其特征在于质谱,元素分析,循环伏安法和单晶x射线衍射.该复合物显示出优异的催化活性,可使用聚甲基氢硅氧烷(pmhs)还原芳香族,杂芳香族,脂肪族和空间拥挤的腈,从而生成伯胺.
Doi:10.1021/acs.Inorgchem.9B01377

专利信息

专利号:US-6815214-B2
优先权日:2000-12-29
标 题 :Pharmaceutical uses and synthesis of diketopiperazines
发明人：BOYCE JIM P; HOWBERT J JEFFRY; TABONE JOHN C
权利人:CELLTECH R & D INC
摘要:The synthesis of novel diketopiperazines, their use in inhibiting cellular events such as those involving NFK-α, NFK-β and in the treatment of inflammation events, a combinatorial library of diverse diketopiperazines and process for their synthesis as a library and as individual compounds. In particular novel diketopiperazines are disclosed including their synthesis and use in cellular events such as activation of the transcription factor, nuclear factor, TNF-α, TNF-β and also apoptosis.

专利号:US-6906046-B2
优先权日:2000-12-22
标题 :Pharmaceutical uses and synthesis of benzobicyclooctanes
发明人：JACKSON RANDY W; DARWISH IHAB; BAUGHMAN TED A; HOWBERT J JEFFRY
权利人:CELLTECH R & D INC
摘要:Benzobicyclooctane compounds, their use in inhibiting cellular events involving TNF-α and IL-8, and in the treatment of inflammation events in general; a combinatorial library of diverse bicyclooctanes and process for their synthesis as a library and as individual compounds.

专利号:US-4935536-A
优先权日:1987-05-21
标 题 :Protecting groups for asparagine and glutamine in peptide synthesis
发明人：HUDSON DEREK
权利人:MILLIPORE CORP
摘要:Trialkoxybenzyl (Taob) protected asparagine and glutamine, a method of synthesis and a method of use are provided. The Taob protected Asn and Gln have the following formulae: ##STR1## wherein Z is an alkyl group having from 1 to 10 carbon atoms; X and W are any α-protecting group which can be selectively removed while maintaining Taob intact; Y is H or any group sufficiently active or activatable to react with NH 2 -- or NHâ•? to generate an amide bond; n is 1 for asparagine or 2 for glutamine. These derivatives are stable in solution, have good solubility in organic solvents and couple directly without side reactions.

专利号:US-6933303-B2
优先权日:2001-10-19
标 题:Heteroaryl-fused nitrogen heterocycles as therapeutic agents
发明人：MJALLI ADNAN M M; ANDREWS ROBERT C; XIE RONGYUAN; YARRAGUNTA RAVINDRA R; REN TAN
权利人:TRANSTECH PHARMA INC
摘要:This invention provides compounds which are useful as inhibitors of protein tyrosine phosphatases (PTPases). As inhibitors of PTPases, the compounds of the invention are useful for the management, treatment, control and adjunct treatment of diseases mediated by PTPase activity. Such diseases include type I diabetes, type II diabetes, immune dysfunction, AIDS, autoimmunity, glucose intolerance, obesity, cancer, psoriasis, allergic diseases, infectious diseases, inflammatory diseases, diseases involving the modulated synthesis of growth hormone or the modulated synthesis of growth factors or cytokines which affect the production of growth hormone, or Alzheimer's disease.

专利号:US-2005080086-A1
优先权日:2000-12-29
标 题 :Pharmaceutical uses and synthesis of diketopiperazines

专利号:US-2003069305-A1
优先权日:2000-12-22
标题:Pharmaceutical uses and synthesis of benzobicyclooctanes