CAS: 41078-65-3; 1,4,5,6-Tetrahydropyrimidin-2-Amine

相似化合物

26893-39-0 1861407-56-8 784137-12-8

上下游产品

2-Amino-4,6-dichloropyrimidine N-Cyanoguanidine Trimethylenediamine 2-aminopyrimidine (2S)-2-Benzyloxycarbonylamino-3-((5-(2-(1,4,5,6-tetrahydropyrimidin-2-ylcarbamoyl)-cyclopropyl)-thiophene-2-carbonyl)-amino)-propionic Acid tert-Butyl Ester tert-butyl ester2-benzyloxycarbonylamino-3-({5-[2-(1,4,5,6-tetrahydro-pyrimidin-2-ylcarbamoyl)-ethyl]-thiophene-2-carbonyl}-amino)-propionic acid tert-butyl ester (2S)-2-(4-tert-Butylphenyl-sulfonylamino)-3-((5-(2-(1,4,5,6-tetrahydropyrimidin-2-ylcarbamoyl)-ethyl)-thiophene-2-carbonyl)-amino)-propionic Acid tert-Butyl Ester (2S)-3-((5-(2-(1,4,5,6-Tetrahydropyrimidin-2-ylcarbamoyl)-ethyl)-thiophene-2-carbonyl)-amino)-2-(4-trifluoromethylphenyl-sulfonylamino)-propionic Acid tert-Butyl Ester

2-氨基-4,6-二氯嘧啶置于palladium On Activated Charcoal,乙醚,水体系中,化学反应生成 2-氨基-1,4,5,6-四氢嘧啶
参考文献:Pyrimidines. V. Dehalogenation And Nuclear Reduction Of Certain Pyrimidines1
标题:Pyrimidines. V. Dehalogenation And Nuclear Reduction Of Certain Pyrimidines1
摘要:
DOI:10.1021/jo01125A004

专利信息

专利号:US-7186827-B2
优先权日:2003-10-30
标题:Dipeptide synthesis
发明人：BUSACCA CARL ALAN; HADDAD NIZAR; KAPADIA SURESH R; SMITH KEENAN LANA; LORENZ JON CHARLES; SENANAYAKE CHRIS HUGH; WEI XUDONG
权利人:BOEHRINGER INGELHEIM PHARMA
摘要:Disclosed are processes of making dipeptide compounds of formula(I) as further described in the detailed description section:

专利号:US-6472403-B2
优先权日:2000-01-20
标 题 :αV integrin receptor antagonists
发明人：DUGGAN MARK E; HALCZENKO WASYL; HUTCHINSON JOHN H; LI AIWEN; MEISSNER ROBERT S; PERKINS JAMES J; STEELE THOMAS G; WANG JIABING; PATANE MICHAEL A
权利人:MERCK & CO INC
摘要:The present invention relates to novel imidazolidinone derivatives thereof, their synthesis, and their use as αv integrin receptor antagonists. More particularly, the compounds of the present invention are antagonists of the integrin receptors αvβ3 and/or αvβ5 and are useful for inhibiting bone resorption, treating and preventing osteoporosis, and inhibiting vascular restenosis, diabetic retinopathy, macular degeneration, angiogenesis, atherosclerosis, inflammation, inflammatory arthritis, viral disease, cancer, and metastatic tumor growth.